Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sydney Shuff"'
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0244792 (2020)
Blood coagulation is central to myocardial ischemia and reperfusion (IR) injury. Studies on the light elicited circadian rhythm protein Period 2 (PER2) using whole body Per2-/- mice found deficient platelet function and reduced clotting which would b
Externí odkaz:
https://doaj.org/article/ac96ea949a694d8793e72a00a756a506
Publikováno v:
Trends in Molecular Medicine. 27:627-629
Angiopoietin-like 4 (ANGPTL4) is critical for regulating plasma lipids, and thus an attractive therapeutic target for cardiovascular diseases. Unfortunately, targeting ANGPTL4 results in a proinflammatory and ultimately lethal phenotype in animals. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d314d7a9e086bca072d8a5693be6251
https://doi.org/10.1016/j.molmed.2021.04.007
https://doi.org/10.1016/j.molmed.2021.04.007
Publikováno v:
Curr Pharm Des
Background: We recently reported a role for the circadian rhythm protein Period 2 (PER2) in midazolam induced cognitive dysfunction. Based on previous studies showing a critical role for the adenosine A2B receptor (ADORA2B) in PER2 regulation, we hyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45e3a60bdb2770c189d9314cade0026d
https://doi.org/10.2174/1381612826666200415171622
https://doi.org/10.2174/1381612826666200415171622
Autor:
Yoshimasa Oyama, Joseph K. Maddry, Steven G. Schauer, Vikhyat S. Bebarta, Tobias Eckle, Sydney Shuff
Publikováno v:
Mil Med
IntroductionHemorrhagic shock is a primary injury amongst combat casualties. Hemorrhagic shock can lead to acute lung injury, which has a high mortality rate. Based on studies showing the role of intense light for organ-protection, we sought to evalu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5b6195d57dfe8abd4cdf04a4d01b115
https://doi.org/10.1093/milmed/usaa088
https://doi.org/10.1093/milmed/usaa088
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 12, p e0244792 (2020)
PLoS ONE, Vol 15, Iss 12, p e0244792 (2020)
Blood coagulation is central to myocardial ischemia and reperfusion (IR) injury. Studies on the light elicited circadian rhythm protein Period 2 (PER2) using whole bodyPer2-/-mice found deficient platelet function and reduced clotting which would be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0888152903b4a8e457df78c8095d724
https://pubmed.ncbi.nlm.nih.gov/33382840
https://pubmed.ncbi.nlm.nih.gov/33382840
Autor:
Cassandra L. Gorsuch, Chan Lee, Zachary T. Schafer, Mark A. Hawk, W. Matthew Leevy, Sung Eun Kim, Lei Jiang, Matyas Abel Tsegaye, Luqun Shen, Jens C. Hamann, Michael Overholtzer, Junjun Zuo, Sarah Chapman, Kelsey J. Weigel, Sydney Shuff, Ralph J. DeBerardinis, Patrick Fagan, Joshua A. Mason, Stephan Hu
Publikováno v:
Nature Cell Biology. 20:272-284
For cancer cells to survive during extracellular matrix (ECM) detachment, they must inhibit anoikis and rectify metabolic deficiencies that cause non-apoptotic cell death. Previous studies in ECM-detached cells have linked non-apoptotic cell death to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::644e9c27b6bd15789f1e3b32223fe59e
https://doi.org/10.1038/s41556-018-0034-2
https://doi.org/10.1038/s41556-018-0034-2
Autor:
Nicholas Pagani, Sydney Shuff, Siyuan Zhang, Brendan Heiden, Raju R. Rayavarapu, Melissa M. Shaw, Zachary T. Schafer
Publikováno v:
Journal of Biological Chemistry. 290:8722-8733
The metastasis of cancer cells from the site of the primary tumor to distant sites in the body represents the most deadly manifestation of cancer. In order for metastasis to occur, cancer cells need to evade anoikis, which is defined as apoptosis cau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fc3929dab160704c23c936f46a331e3
https://doi.org/10.1074/jbc.m114.612754
https://doi.org/10.1074/jbc.m114.612754