Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Sydney Lim"'
Autor:
Sadhana Ravikumar, Amanda E. Denning, Sydney Lim, Eunice Chung, Niyousha Sadeghpour, Ranjit Ittyerah, Laura E. M. Wisse, Sandhitsu R. Das, Long Xie, John L. Robinson, Theresa Schuck, Edward B. Lee, John A. Detre, M. Dylan Tisdall, Karthik Prabhakaran, Gabor Mizsei, Maria Mercedes Iñiguez de Onzono Martin, Maria del Mar Arroyo Jiménez, Monica Mũnoz, Maria del Pilar Marcos Rabal, Sandra Cebada Sánchez, José Carlos Delgado González, Carlos de la Rosa Prieto, David J. Irwin, David A. Wolk, Ricardo Insausti, Paul A. Yushkevich
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Our current understanding of the spread and neurodegenerative effects of tau neurofibrillary tangles (NFTs) within the medial temporal lobe (MTL) during the early stages of Alzheimer’s Disease (AD) is limited by the presence of confounding
Externí odkaz:
https://doaj.org/article/056f36ce471b4eba989dc86723aa6f3b
Autor:
Sadhana Ravikumar, Laura E. M. Wisse, Sydney Lim, Ranjit Ittyerah, Long Xie, Madigan L. Bedard, Sandhitsu R. Das, Edward B. Lee, M. Dylan Tisdall, Karthik Prabhakaran, Jacqueline Lane, John A. Detre, Gabor Mizsei, John Q. Trojanowski, John L. Robinson, Theresa Schuck, Murray Grossman, Emilio Artacho-Pérula, Maria Mercedes Iñiguez de Onzoño Martin, María del Mar Arroyo Jiménez, Monica Muñoz, Francisco Javier Molina Romero, Maria del Pilar Marcos Rabal, Sandra Cebada Sánchez, José Carlos Delgado González, Carlos de la Rosa Prieto, Marta Córcoles Parada, David J. Irwin, David A. Wolk, Ricardo Insausti, Paul A. Yushkevich
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-14 (2021)
Abstract Tau neurofibrillary tangle (NFT) pathology in the medial temporal lobe (MTL) is closely linked to neurodegeneration, and is the early pathological change associated with Alzheimer’s disease (AD). To elucidate patterns of structural change
Externí odkaz:
https://doaj.org/article/02f2ccda7bf044fba3c690c986dda924
Autor:
M. Dylan Tisdall, Daniel T. Ohm, Rebecca Lobrovich, Sandhitsu R. Das, Gabor Mizsei, Karthik Prabhakaran, Ranjit Ittyerah, Sydney Lim, Corey T. McMillan, David A. Wolk, James Gee, John Q. Trojanowski, Edward B. Lee, John A. Detre, Paul Yushkevich, Murray Grossman, David J. Irwin
Publikováno v:
NeuroImage: Clinical, Vol 33, Iss , Pp 102913- (2022)
Frontotemporal lobar degeneration (FTLD) is a heterogeneous spectrum of age-associated neurodegenerative diseases that include two main pathologic categories of tau (FTLD-Tau) and TDP-43 (FTLD-TDP) proteinopathies. These distinct proteinopathies are
Externí odkaz:
https://doaj.org/article/bdcc86440dd24ea7bdac41da36329d85
Autor:
Hyung Seok Roh, David J. Irwin, Mónica Muñoz López, Maria Mercedes Iñiguez de Onzoño Martin, Ranjit Ittyerah, Sydney Lim, Madigan L. Bedard, John L. Robinson, Theresa Schuck, Emilio Artacho-Pérula, María del Mar Arroyo Jiménez, María Pilar Marcos Rabal, Francisco Javier Molina Romero, Sandra Cebada Sánchez, José Carlos Delgado González, Carlos de la Rosa-Prieto, Marta Córcoles Parada, Edward B. Lee, Daniel T. Ohm, Laura E. M. Wisse, David A. Wolk, James C. Gee, Ricardo Insausti, Paul A. Yushkevich, Min Chen
Publikováno v:
Medical Imaging 2023: Digital and Computational Pathology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9e01cb6831c5962ce25b57e8c526575
https://doi.org/10.1117/12.2651848
https://doi.org/10.1117/12.2651848
Autor:
Molly Ungrady, David J. Irwin, Sydney Lim, Paul A. Yushkevich, Ranjit Ittyerah, Sandhitsu R. Das, Murray Grossman, Laura E.M. Wisse, David A. Wolk
Publikováno v:
Neurobiol Aging
INTRODUCTION: T1-MRI studies report early atrophy in the left anterior temporal lobe, especially the perirhinal cortex (PRC), in semantic variant Primary Progressive Aphasia (svPPA). Improved segmentation protocols using high-resolution T2-MRI have e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffe4426669c68e301ecdef7b284e83d1
https://doi.org/10.1016/j.neurobiolaging.2020.11.012
https://doi.org/10.1016/j.neurobiolaging.2020.11.012
Autor:
Long Xie, Laura E.M. Wisse, Jiancong Wang, Sadhana Ravikumar, Pulkit Khandelwal, Trevor Glenn, Anica Luther, Sydney Lim, David A. Wolk, Paul A. Yushkevich
Publikováno v:
Medical image analysis. 83
Deep convolutional neural networks (DCNN) achieve very high accuracy in segmenting various anatomical structures in medical images but often suffer from relatively poor generalizability. Multi-atlas segmentation (MAS), while less accurate than DCNN i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::491f0fe12fbf0845e4694a1331c12b50
https://pubmed.ncbi.nlm.nih.gov/36379194
https://pubmed.ncbi.nlm.nih.gov/36379194
Autor:
M. Dylan Tisdall, Daniel T. Ohm, Rebecca Lobrovich, Sandhitsu R. Das, Gabor Mizsei, Karthik Prabhakaran, Ranjit Ittyerah, Sydney Lim, Corey T. McMillan, David A. Wolk, James Gee, John Q. Trojanowski, Edward B. Lee, John A. Detre, Paul Yushkevich, Murray Grossman, David J. Irwin
Publikováno v:
NeuroImage : Clinical
NeuroImage: Clinical, Vol 33, Iss, Pp 102913-(2022)
NeuroImage: Clinical, Vol 33, Iss, Pp 102913-(2022)
Graphical abstract
Highlights • Comparative study of whole-hemisphere ex vivo T2*-weighted MRI and histopathology. • Sample of FTLD-Tau and FTLD-TDP subtypes with reference to healthy and AD brain. • Novel focal upper cortical-layer iron-r
Highlights • Comparative study of whole-hemisphere ex vivo T2*-weighted MRI and histopathology. • Sample of FTLD-Tau and FTLD-TDP subtypes with reference to healthy and AD brain. • Novel focal upper cortical-layer iron-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbdf51e7e87a9de0d2a9bfe8d6f7cc57
http://europepmc.org/articles/PMC8715243
http://europepmc.org/articles/PMC8715243
Autor:
John A. Detre, Carlos de la Rosa Prieto, M. Dylan Tisdall, Francisco Javier Molina Romero, Ricardo Insausti, Jacqueline M. Lane, Maria del Pilar Marcos Rabal, Theresa Schuck, Paul A. Yushkevich, Emilio Artacho-Pérula, María del Mar Arroyo Jiménez, Ranjit Ittyerah, Sydney Lim, Edward B. Lee, Monica Munoz, Sadhana Ravikumar, Sandhitsu R. Das, Murray Grossman, Long Xie, John L. Robinson, David J. Irwin, Karthik Prabhakaran, Gabor Mizsei, Laura E.M. Wisse, Maria Mercedes Iniguez de Onzono Martin, Madigan L. Bedard, José Carlos Delgado González, David A. Wolk, Sandra Cebada Sánchez, John Q. Trojanowski, Marta Córcoles Parada
Publikováno v:
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-14 (2021)
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-14 (2021)
Tau neurofibrillary tangle (NFT) pathology in the medial temporal lobe (MTL) is closely linked to neurodegeneration, and is the early pathological change associated with Alzheimer’s disease (AD). To elucidate patterns of structural change in the MT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec40cc1360f9e611bda1b33fc3e49229
https://doi.org/10.1186/s40478-021-01275-7
https://doi.org/10.1186/s40478-021-01275-7
Autor:
Edward B. Lee, Jacqueline M. Lane, M P Marcos Rabal, Karthik Prabhakaran, F J Molina Romero, M L Bedard, Maria del Mar Arroyo-Jimenez, David J. Irwin, Laura E.M. Wisse, Emilio Artacho-Pérula, M. D. Tisdall, David A. Wolk, John Q. Trojanowski, M M de Iñiguez de Onzono Martin, Ricardo Insausti, J C Delgado González, Paul A. Yushkevich, M Córcoles Parada, Ranjit Ittyerah, Sadhana Ravikumar, Murray Grossman, Sydney Lim, S Cebada Sánchez, Sandhitsu R. Das, Long Xie, Gabor Mizsei, John A. Detre, Theresa Schuck, C de la Rosa Prieto, M Muñoz Lopez
Publikováno v:
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-11 (2021)
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-11 (2021)
The medial temporal lobe (MTL) is a nidus for neurodegenerative pathologies and therefore an important region in which to study polypathology. We investigated associations between neurodegenerative pathologies and the thickness of different MTL subre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3e2d522d56bff8280724b1601fd9d0e
https://pubmed.ncbi.nlm.nih.gov/34289895
https://pubmed.ncbi.nlm.nih.gov/34289895
Autor:
Rebecca Lobrovich, Corey T. McMillan, Edward B. Lee, Karthik Prabhakaran, John Q. Trojanowski, Gabor Mizsei, Daniel T. Ohm, David A. Wolk, James C. Gee, Paul A. Yushkevich, Ranjit Ittyerah, David J. Irwin, Murray Grossman, Sydney Lim, Sandhitsu R. Das, M. Dylan Tisdall, John A. Detre
Frontotemporal lobar degeneration (FTLD) is a heterogeneous spectrum of age-associated neurodegenerative diseases that include two main pathologic categories of tau (FTLD-Tau) and TDP-43 (FTLD-TDP) proteinopathies. These distinct proteinopathies are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb77111a69b02ae4424bc5c7f7949237
https://doi.org/10.1101/2021.04.14.439064
https://doi.org/10.1101/2021.04.14.439064
