Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sydney K Vaughan"'
Autor:
Ryan Castro, Thomas Taetzsch, Sydney K Vaughan, Kerilyn Godbe, John Chappell, Robert E Settlage, Gregorio Valdez
Publikováno v:
eLife, Vol 9 (2020)
Perisynaptic Schwann cells (PSCs) are specialized, non-myelinating, synaptic glia of the neuromuscular junction (NMJ), that participate in synapse development, function, maintenance, and repair. The study of PSCs has relied on an anatomy-based approa
Externí odkaz:
https://doaj.org/article/1be4c178b8f042e7815c81916532d5f5
Autor:
Sydney K Vaughan, Kerilyn Godbe, Ryan Castro, Thomas Taetzsch, John C. Chappell, Gregorio Valdez, Robert E. Settlage
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
Perisynaptic Schwann cells (PSCs) are specialized, non-myelinating, synaptic glia of the neuromuscular junction (NMJ), that participate in synapse development, function, maintenance, and repair. The study of PSCs has relied on an anatomy-based approa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86b2d4feed828dcff87185e61705cac0
https://doi.org/10.7554/elife.56935
https://doi.org/10.7554/elife.56935
Autor:
Gregorio Valdez, John C. Chappell, Sydney K Vaughan, Robert E. Settlage, Thomas Taetzsch, Ryan Castro, Keri Godbe
The inability to specifically identify and manipulate synaptic glial cells remains a major obstacle to understanding fundamental aspects of synapse formation, stability and repair. Using a combinatorial gene expression approach, we discovered molecul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaf61b16db4d4db21d0e8dfdc78eca92
Publikováno v:
Frontiers in Aging Neuroscience, Vol 11 (2019)
Frontiers in Aging Neuroscience
Frontiers in Aging Neuroscience
In addition to driving contraction of skeletal muscles, acetylcholine (ACh) acts as an anti-synaptogenic agent at neuromuscular junctions (NMJs). Previous studies suggest that aging is accompanied by increases in cholinergic activity at the NMJ, whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::689b16af4f162a1c0b606e0da6fec2b7
https://www.frontiersin.org/article/10.3389/fnagi.2019.00262/full
https://www.frontiersin.org/article/10.3389/fnagi.2019.00262/full
Autor:
Theo Hatzipetros, Fernando G. Vieira, Sydney K. Vaughan, Natalia M. Sutherland, Gregorio Valdez, Sihui Zhang
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
There is increased recognition that sensory neurons located in dorsal root ganglia (DRG) are affected in amyotrophic lateral sclerosis (ALS). However, it remains unknown whether ALS-inducing factors, other than mutant superoxide dismutase 1 (SOD1G93A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d9ab60a1343914a081c5e6aee5520a5
https://doi.org/10.1038/s41598-018-34510-8
https://doi.org/10.1038/s41598-018-34510-8
Autor:
Diogo Guimarães, Cristina Guatimosim, Jéssica Neves Andrade, Silvia Guatimosim, Vânia F. Prado, Matheus P.S. Magalhães-Gomes, Grace S. Pereira, Patrícia Massara Martinelli, Luana Pereira Leite Schetino, Sydney K. Vaughan, Cristiane P. Bastos, Daisy Motta-Santos, Marco A. M. Prado, Candido Celso Coimbra, Gregorio Valdez
Publikováno v:
Anatomy and Cell Biology Publications
Congenital myasthenic syndromes (CMS) result from reduced cholinergic transmission at neuromuscular junctions (NMJs). While the etiology of CMS varies, the disease is characterized by muscle weakness. To date, it remains unknown if CMS causes long-te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46b9e541109f202a0657228ef969183a
https://ir.lib.uwo.ca/anatomypub/143
https://ir.lib.uwo.ca/anatomypub/143
Autor:
Sydney K, Vaughan, Natalia M, Sutherland, Sihui, Zhang, Theo, Hatzipetros, Fernando, Vieira, Gregorio, Valdez
Publikováno v:
Scientific Reports
There is increased recognition that sensory neurons located in dorsal root ganglia (DRG) are affected in amyotrophic lateral sclerosis (ALS). However, it remains unknown whether ALS-inducing factors, other than mutant superoxide dismutase 1 (SOD1G93A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::34a26f011a86880db4eaa6127f59a637
https://pubmed.ncbi.nlm.nih.gov/30410094
https://pubmed.ncbi.nlm.nih.gov/30410094
Publikováno v:
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. :glw175
The impact of aging on proprioceptive sensory neurons and intrafusal muscle fibers (IMFs) remains largely unexplored despite the central function these cells play in modulating voluntary movements. Here, we show that proprioceptive sensory neurons un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66778a3401fbf4ae123d2debbc44cc85
https://doi.org/10.1093/gerona/glw175
https://doi.org/10.1093/gerona/glw175
Publikováno v:
Journal of Comparative Neurology. 523:Spc1-Spc1
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that primarily targets the motor system. Although much is known about the effects of ALS on motor neurons and glial cells, little is known about its effect on proprioceptive sensory n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7789fc6dd4e13d1550253f9616f72b13
https://doi.org/10.1002/cne.23906
https://doi.org/10.1002/cne.23906