Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Sydney C W Tang"'
Autor:
Wai Han Yiu, Dickson W L Wong, Loretta Y Y Chan, Joseph C K Leung, Kwok Wah Chan, Hui Yao Lan, Kar Neng Lai, Sydney C W Tang
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88894 (2014)
Tissue kallikrein (KLK1) expression is up-regulated in human diabetic kidney tissue and induced by high glucose (HG) in human proximal tubular epithelial cells (PTEC). Since the kallikrein-kinin system (KKS) has been linked to cellular inflammatory p
Externí odkaz:
https://doaj.org/article/461f80e8003f413c9fc02858f4d40d16
Autor:
Hao Jia Wu, Wai Han Yiu, Rui Xi Li, Dickson W L Wong, Joseph C K Leung, Loretta Y Y Chan, Yuelin Zhang, Qizhou Lian, Miao Lin, Hung Fat Tse, Kar Neng Lai, Sydney C W Tang
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90883 (2014)
Bone marrow-derived mesenchymal stem cells (BM-MSCs) have recently shown promise as a therapeutic tool in various types of chronic kidney disease (CKD) models. However, the mechanism of action is incompletely understood. As renal prognosis in CKD is
Externí odkaz:
https://doaj.org/article/57419aea3cdf445aa9cabd84538a4876
Autor:
Lijun Ma, Mariana Murea, James A Snipes, Alejandra Marinelarena, Jacqueline Krüger, Pamela J Hicks, Kurt A Langberg, Meredith A Bostrom, Jessica N Cooke, Daisuke Suzuki, Tetsuya Babazono, Takashi Uzu, Sydney C W Tang, Ashis K Mondal, Neeraj K Sharma, Sayuko Kobes, Peter A Antinozzi, Matthew Davis, Swapan K Das, Neda Rasouli, Philip A Kern, Nathan J Shores, Lawrence L Rudel, Matthias Blüher, Michael Stumvoll, Donald W Bowden, Shiro Maeda, John S Parks, Peter Kovacs, Robert L Hanson, Leslie J Baier, Steven C Elbein, Barry I Freedman
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56193 (2013)
Acetyl coenzyme A carboxylase B gene (ACACB) single nucleotide polymorphism (SNP) rs2268388 is reproducibly associated with type 2 diabetes (T2DM)-associated nephropathy (DN). ACACB knock-out mice are also protected from obesity. This study assessed
Externí odkaz:
https://doaj.org/article/b096f420e3c542b4a42f8262f5ee7a6d
Autor:
Hongyu Li, Joseph C. K. Leung, Wai Han Yiu, Loretta Y. Y. Chan, Bin Li, Sarah W. Y. Lok, Rui Xue, Yixin Zou, Kar Neng Lai, Sydney C. W. Tang
Publikováno v:
Cell Death and Disease, Vol 13, Iss 12, Pp 1-15 (2022)
Abstract Mitochondria take part in a network of intracellular processes that regulate homeostasis. Defects in mitochondrial function are key pathophysiological changes during AKI. Although Wnt/β-catenin signaling mediates mitochondrial dysfunction i
Externí odkaz:
https://doaj.org/article/82f9885eca8b4c88bf8be3fca5551bed
Autor:
Anthony T. P. Chan, Sydney C. W. Tang
Publikováno v:
Kidney Research and Clinical Practice, Vol 41, Iss 6, Pp 682-698 (2022)
Progress in the treatment of diabetic kidney disease (DKD) has been modest since the early trials on renin-angiotensin-aldosterone system inhibitors (RAASis). Although sodium-glucose co-transporter 2 inhibitors (SGLT2is) have revolutionized the manag
Externí odkaz:
https://doaj.org/article/5cc29bf33fd94eb2840ef30055cbdc4e
Autor:
Gordon Chun Kau Chan, Chun Ka Wong, Benjamin Y. F. So, Jack Kit Chung Ng, Grace Chung Yan Lui, Cheuk Chun Szeto, Ivan Fan Ngai Hung, Hung Fat Tse, Sydney C. W. Tang, Tak Mao Chan, Kai Ming Chow, Desmond Y. H. Yap
Publikováno v:
Frontiers in Medicine, Vol 9 (2023)
BackgroundHyponatremia is common in COVID-19, but its epidemiology and impact on clinical outcomes in relation to different variants, especially the Omicron variant, requires further clarification.MethodsThis was a territory-wide retrospective study
Externí odkaz:
https://doaj.org/article/b612347f2e544802842845f6655e2bb8
Autor:
Jiaoyi Chen, Xiao Ru Huang, Fuye Yang, Wai Han Yiu, Xueqing Yu, Sydney C. W. Tang, Hui Yao Lan
Publikováno v:
Advanced Science, Vol 9, Iss 18, Pp n/a-n/a (2022)
Abstract Previously, this study demonstrates the critical role of myeloid specific TLR4 in macrophage‐mediated progressive renal injury in anti‐glomerular basement membrane (anti‐GBM) crescentic glomerulonephritis (cGN); however, the underlying
Externí odkaz:
https://doaj.org/article/3a2da85265024b5ebd8877932fe364a6
Autor:
Qixia Shen, Yucheng Wang, Jiaoyi Chen, Lifeng Ma, Xiaoru Huang, Sydney C. W. Tang, Huiyao Lan, Hong Jiang, Jianghua Chen
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Allograft rejection is a common immunological feature in renal transplantation and is associated with reduced graft survival. A mouse renal allograft rejection model was induced and single-cell RNA sequencing (scRNA-seq) data of CD45+ leukocytes in k
Externí odkaz:
https://doaj.org/article/6340c25fe1354964b3b602a9cc2f778a
Autor:
Wai Han Yiu, Kam Wa Chan, Loretta Y. Y. Chan, Joseph C. K. Leung, Kar Neng Lai, Sydney C. W. Tang
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Spleen tyrosine kinase (Syk) is a non-receptor tyrosine kinase involved in signal transduction in a variety of immune responses. It has been demonstrated that Syk plays a pathogenic role in orchestrating inflammatory responses and cell proliferation
Externí odkaz:
https://doaj.org/article/a4a3de2399374b749e791af0560293a5
Autor:
Suceena Alexander, Sanjiv Jasuja, Maurizio Gallieni, Manisha Sahay, Devender S. Rana, Vivekanand Jha, Shalini Verma, Raja Ramachandran, Vinant Bhargava, Gaurav Sagar, Anupam Bahl, Mamun Mostafi, Jayakrishnan K Pisharam, Sydney C. W. Tang, Chakko Jacob, Atma Gunawan, Goh B. Leong, Khin T. Thwin, Rajendra K Agrawal, Kriengsak Vareesangthip, Roberto Tanchanco, Lina H. L. Choong, Chula Herath, Chih C. Lin, Nguyen T. Cuong, Ha P. Haian, Syed F Akhtar, Ali Alsahow, Mohan M. Rajapurkar, Vijay Kher, Hemant Mehta, Anil K. Bhalla, Umesh B. Khanna, Deepak S. Ray, Sonika Puri, Himanshu Jain, Aida Lydia, Tushar Vachharajani
Publikováno v:
International Journal of Nephrology, Vol 2021 (2021)
Background. The association between economic status and kidney disease is incompletely explored even in countries with higher economy (HE); the situation is complex in lower economies (LE) of South Asia and Southeast Asia (SA and SEA). Methods. Fifte
Externí odkaz:
https://doaj.org/article/10d48738a00041b5a98dfcd32fdaffd8