Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Syd Johnson"'
Autor:
Paola Circosta, Angela Rita Elia, Indira Landra, Rodolfo Machiorlatti, Maria Todaro, Sabrina Aliberti, Davide Brusa, Silvia Deaglio, Sabina Chiaretti, Riccardo Bruna, Daniela Gottardi, Massimo Massaia, Filomena Di Giacomo, Anna Rita Guarini, Robin Foà, Peter W. Kyriakides, Rohan Bareja, Olivier Elemento, Gurunadh R. Chichili, Emanuele Monteleone, Paul A. Moore, Syd Johnson, Ezio Bonvini, Alessandro Cignetti, Giorgio Inghirami
Publikováno v:
OncoImmunology, Vol 7, Iss 4 (2018)
Many patients with B-cell malignancies can be successfully treated, although tumor eradication is rarely achieved. T-cell-directed killing of tumor cells using engineered T-cells or bispecific antibodies is a promising approach for the treatment of h
Externí odkaz:
https://doaj.org/article/c9f24a2e69284c5786bd71c31922ae7b
Autor:
Amelia K. Pinto, James D. Brien, Chia-Ying Kao Lam, Syd Johnson, Cindy Chiang, John Hiscott, Vanessa V. Sarathy, Alan D. Barrett, Sujan Shresta, Michael S. Diamond
Publikováno v:
mBio, Vol 6, Iss 5 (2015)
ABSTRACT With over 3.5 billion people at risk and approximately 390 million human infections per year, dengue virus (DENV) disease strains health care resources worldwide. Previously, we and others established models for DENV pathogenesis in mice tha
Externí odkaz:
https://doaj.org/article/27a57dee613941a18b597207c172d473
Autor:
Derek D Sloan, Chia-Ying Kao Lam, Alivelu Irrinki, Liqin Liu, Angela Tsai, Craig S Pace, Jasmine Kaur, Jeffrey P Murry, Mini Balakrishnan, Paul A Moore, Syd Johnson, Jeffrey L Nordstrom, Tomas Cihlar, Scott Koenig
Publikováno v:
PLoS Pathogens, Vol 11, Iss 11, p e1005233 (2015)
HIV reservoirs and production of viral antigens are not eliminated in chronically infected participants treated with combination antiretroviral therapy (cART). Novel therapeutic strategies aiming at viral reservoir elimination are needed to address c
Externí odkaz:
https://doaj.org/article/b748f788913f41528226c5ca0c716a56
Autor:
Melissa A Edeling, S Kyle Austin, Bimmi Shrestha, Kimberly A Dowd, Swati Mukherjee, Christopher A Nelson, Syd Johnson, Manu N Mabila, Elizabeth A Christian, Joseph Rucker, Theodore C Pierson, Michael S Diamond, Daved H Fremont
Publikováno v:
PLoS Pathogens, Vol 10, Iss 4, p e1004072 (2014)
We recently described our most potently neutralizing monoclonal antibody, E106, which protected against lethal Dengue virus type 1 (DENV-1) infection in mice. To further understand its functional properties, we determined the crystal structure of E10
Externí odkaz:
https://doaj.org/article/2e886409b57a4c2e80d053bbf06bccf9
Autor:
Katherine L. Williams, Soila Sukupolvi-Petty, Martina Beltramello, Syd Johnson, Federica Sallusto, Antonio Lanzavecchia, Michael S. Diamond, Eva Harris
Publikováno v:
PLoS Pathogens, Vol 9, Iss 3 (2013)
Externí odkaz:
https://doaj.org/article/5de03caf038f435e8dbc910880d4783f
Autor:
Katherine L Williams, Soila Sukupolvi-Petty, Martina Beltramello, Syd Johnson, Federica Sallusto, Antonio Lanzavecchia, Michael S Diamond, Eva Harris
Publikováno v:
PLoS Pathogens, Vol 9, Iss 2, p e1003157 (2013)
Dengue hemorrhagic fever and dengue shock syndrome (DHF/DSS) are life-threatening complications following infection with one of the four serotypes of dengue virus (DENV). At present, no vaccine or antiviral therapies are available against dengue. Her
Externí odkaz:
https://doaj.org/article/c78c796ff7084602811749eb968e4d7a
Autor:
Pankaj Pal, Kimberly A Dowd, James D Brien, Melissa A Edeling, Sergey Gorlatov, Syd Johnson, Iris Lee, Wataru Akahata, Gary J Nabel, Mareike K S Richter, Jolanda M Smit, Daved H Fremont, Theodore C Pierson, Mark T Heise, Michael S Diamond
Publikováno v:
PLoS Pathogens, Vol 9, Iss 4, p e1003312 (2013)
Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus that causes global epidemics of a debilitating polyarthritis in humans. As there is a pressing need for the development of therapeutic agents, we screened 230 new mouse anti-CHIKV monoclo
Externí odkaz:
https://doaj.org/article/ff8cc6d219204c04bb30a4d8c649dab2
Autor:
Adam R. Root, Wei Cao, Bilian Li, Peter LaPan, Caryl Meade, Jocelyn Sanford, Macy Jin, Cliona O’Sullivan, Emma Cummins, Matthew Lambert, Alfredo D. Sheehan, Weijun Ma, Scott Gatto, Kelvin Kerns, Khetemenee Lam, Aaron M. D’Antona, Lily Zhu, William A. Brady, Susan Benard, Amy King, Tao He, Lisa Racie, Maya Arai, Dianah Barrett, Wayne Stochaj, Edward R. LaVallie, James R. Apgar, Kristine Svenson, Lidia Mosyak, Yinhua Yang, Gurunadh R. Chichili, Liqin Liu, Hua Li, Steve Burke, Syd Johnson, Ralph Alderson, William J. J. Finlay, Laura Lin, Stéphane Olland, William Somers, Ezio Bonvini, Hans-Peter Gerber, Chad May, Paul A. Moore, Lioudmila Tchistiakova, Laird Bloom
Publikováno v:
Antibodies, Vol 5, Iss 1, p 6 (2016)
Bispecific antibodies offer a promising approach for the treatment of cancer but can be challenging to engineer and manufacture. Here we report the development of PF-06671008, an extended-half-life dual-affinity re-targeting (DART®) bispecific molec
Externí odkaz:
https://doaj.org/article/8c0c6589f19a4745bedbcd5e1b1c60a5
Autor:
S Kyle Austin, Kimberly A Dowd, Bimmi Shrestha, Christopher A Nelson, Melissa A Edeling, Syd Johnson, Theodore C Pierson, Michael S Diamond, Daved H Fremont
Publikováno v:
PLoS Pathogens, Vol 8, Iss 10, p e1002930 (2012)
We previously developed a panel of neutralizing monoclonal antibodies against Dengue virus (DENV)-1, of which few exhibited inhibitory activity against all DENV-1 genotypes. This finding is consistent with reports observing variable neutralization of
Externí odkaz:
https://doaj.org/article/1b208d14ff4c44678b1d5ccad2b34bc2
Autor:
Bimmi Shrestha, James D Brien, Soila Sukupolvi-Petty, S Kyle Austin, Melissa A Edeling, Taekyung Kim, Katie M O'Brien, Christopher A Nelson, Syd Johnson, Daved H Fremont, Michael S Diamond
Publikováno v:
PLoS Pathogens, Vol 6, Iss 4, p e1000823 (2010)
Antibody protection against flaviviruses is associated with the development of neutralizing antibodies against the viral envelope (E) protein. Prior studies with West Nile virus (WNV) identified therapeutic mouse and human monoclonal antibodies (MAbs
Externí odkaz:
https://doaj.org/article/df704f99bc524bef9b9a3a5bc6a7a1a1