Zobrazeno 1 - 10
of 252
pro vyhledávání: '"Syd Johnson"'
Autor:
Syd Johnson, Ezio Bonvini, Jennie Mather, Scott Koenig, Francine Z. Chen, Jennifer G. Brown, Douglas H. Smith, Liqin Liu, Gurunadh R. Chichili, Deryk Loo, Arash Adami, Peter Young, Kathy L. King, Sergey Gorlatov, Monica Licea, Ann Easton, Jeff Hooley, Claudia B. Fieger, Hua Li, Valentina Ciccarone, Steve Burke, Jonathan C. Li, Daorong Liu, Vatana Long, Penny Roberts, Ralph Alderson, Yinhua Yang, Kalpana Shah, Paul A. Moore
We have developed MGD007 (anti-glycoprotein A33 x anti-CD3), a DART protein designed to redirect T cells to target gpA33 expressing colon cancer. The gpA33 target was selected on the basis of an antibody-based screen to identify cancer antigens unive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ba6d82666632826560f5e8ab30de076
https://doi.org/10.1158/1535-7163.c.6538044.v1
https://doi.org/10.1158/1535-7163.c.6538044.v1
Autor:
Syd Johnson, Ezio Bonvini, Jennie Mather, Scott Koenig, Francine Z. Chen, Jennifer G. Brown, Douglas H. Smith, Liqin Liu, Gurunadh R. Chichili, Deryk Loo, Arash Adami, Peter Young, Kathy L. King, Sergey Gorlatov, Monica Licea, Ann Easton, Jeff Hooley, Claudia B. Fieger, Hua Li, Valentina Ciccarone, Steve Burke, Jonathan C. Li, Daorong Liu, Vatana Long, Penny Roberts, Ralph Alderson, Yinhua Yang, Kalpana Shah, Paul A. Moore
Supplementary Table 1: Sixteen-locus STR analysis of tumor tissue and banked CSLC lines Supplementary Table 2: CSLC derivation and characteristics Supplementary Table 3: Immunohistochemical Analysis of Colorectal Cancer Tumor Specimens Supplementary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27335580a8bd3d29129ed45c0ef17bde
https://doi.org/10.1158/1535-7163.22505397
https://doi.org/10.1158/1535-7163.22505397
Autor:
Ezio Bonvini, Syd Johnson, Paul A. Moore, Scott Koenig, Jeffrey L. Nordstrom, Margaret D. Lewis, Ralph Alderson, Jennifer Brown, Sergey Gorlatov, Steve Burke, Linda Jin, Hua Li, Yinhua Yang, Lusiana Widjaja, Vatana Long, Chia-Ying K. Lam, Liqin Liu
MGD011 mediated concentration-dependent cytotoxicity against CD19+ HBL-2 and Jeko-1 lymphoma cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::771ff285615f1e5d28d86b70691575b7
https://doi.org/10.1158/1078-0432.22465037
https://doi.org/10.1158/1078-0432.22465037
Autor:
Ezio Bonvini, Syd Johnson, Paul A. Moore, Scott Koenig, Jeffrey L. Nordstrom, Margaret D. Lewis, Ralph Alderson, Jennifer Brown, Sergey Gorlatov, Steve Burke, Linda Jin, Hua Li, Yinhua Yang, Lusiana Widjaja, Vatana Long, Chia-Ying K. Lam, Liqin Liu
Supplemental figure legends for supplemental figures S1, S2, S3, S4, S5, S6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6203eda031d4d730fd3422fc722bd1e0
https://doi.org/10.1158/1078-0432.22465046.v1
https://doi.org/10.1158/1078-0432.22465046.v1
Autor:
Paul A. Moore, Ezio Bonvini, Syd Johnson, Stanford J. Stewart, Scott Koenig, Jennie P. Mather, Tony W. Liang, Claudia Fieger, Monica Licea, Jill R. Rillema, Jonathan C. Li, Ann N. Easton, Yan Chen, Tom Son, Yinhua Yang, Hua Li, Valentina Ciccarone, Steve Burke, Sergey Gorlatov, Wenjun Zhang, Ling Huang, Francine Z. Chen, Ralph F. Alderson, Deryk Loo
PDF file, 75KB, Expression level of B7-H3 on ATCC cancer cell lines as determined by FLOW cytometry with anti-B7-H3 mAb BRCA84D. Solid curves represent isotype control staining; open curves represent staining with FI.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66a7396395671beca990878b868aa69d
https://doi.org/10.1158/1078-0432.22447001
https://doi.org/10.1158/1078-0432.22447001
Autor:
Paul A. Moore, Ezio Bonvini, Syd Johnson, Stanford J. Stewart, Scott Koenig, Jennie P. Mather, Tony W. Liang, Claudia Fieger, Monica Licea, Jill R. Rillema, Jonathan C. Li, Ann N. Easton, Yan Chen, Tom Son, Yinhua Yang, Hua Li, Valentina Ciccarone, Steve Burke, Sergey Gorlatov, Wenjun Zhang, Ling Huang, Francine Z. Chen, Ralph F. Alderson, Deryk Loo
PDF file, 78KB, Measurement of the absolute level of circulating B cells (CD20+; Panel A), T cells (CD3+; Panel B) and NK cells (CD159a+)Panel C) in blood samples collected from cynomolgus monkeys at the indicated days prior to administration (Day -2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6713e2ca3fa83c5b06a09b2b9865e32
https://doi.org/10.1158/1078-0432.22446992.v1
https://doi.org/10.1158/1078-0432.22446992.v1
Autor:
Paul A. Moore, Ezio Bonvini, Syd Johnson, Stanford J. Stewart, Scott Koenig, Jennie P. Mather, Tony W. Liang, Claudia Fieger, Monica Licea, Jill R. Rillema, Jonathan C. Li, Ann N. Easton, Yan Chen, Tom Son, Yinhua Yang, Hua Li, Valentina Ciccarone, Steve Burke, Sergey Gorlatov, Wenjun Zhang, Ling Huang, Francine Z. Chen, Ralph F. Alderson, Deryk Loo
PDF file, 89KB, Measurement of IL-5 (Panel A), IL-6 (Panel B) and TNF-B (Panel C) cytokine levels in serum samples collected from cynomolgus monkeys prior to infusion (Pre) or at the indicated time points following intravenous administration of PBS v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::170a84c2e2cb77a54536a2580cb2eec2
https://doi.org/10.1158/1078-0432.22446995
https://doi.org/10.1158/1078-0432.22446995
Autor:
Ezio Bonvini, Syd Johnson, Paul A. Moore, Scott Koenig, Jeffrey L. Nordstrom, Margaret D. Lewis, Ralph Alderson, Jennifer Brown, Sergey Gorlatov, Steve Burke, Linda Jin, Hua Li, Yinhua Yang, Lusiana Widjaja, Vatana Long, Chia-Ying K. Lam, Liqin Liu
Purpose: CD19, a B-cell lineage-specific marker, is highly represented in B-cell malignancies and an attractive target for therapeutic interventions. MGD011 is a CD19 x CD3 DART bispecific protein designed to redirect T lymphocytes to eliminate CD19-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::406b8a53289a88a61dc0b38cd55ce3ad
https://doi.org/10.1158/1078-0432.c.6525905
https://doi.org/10.1158/1078-0432.c.6525905
Autor:
Ezio Bonvini, Syd Johnson, Paul A. Moore, Scott Koenig, Jeffrey L. Nordstrom, Margaret D. Lewis, Ralph Alderson, Jennifer Brown, Sergey Gorlatov, Steve Burke, Linda Jin, Hua Li, Yinhua Yang, Lusiana Widjaja, Vatana Long, Chia-Ying K. Lam, Liqin Liu
Supplemental Table 1: MGD011 repeat-dose and dose-escalation study design in non-human primates; Supplemental Table 2: PK properties of MGD011 derived from non-human primate studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f3e7ddc721928fb8e090c1891c28603
https://doi.org/10.1158/1078-0432.22465025.v1
https://doi.org/10.1158/1078-0432.22465025.v1
Autor:
Paul A. Moore, Ezio Bonvini, Syd Johnson, Stanford J. Stewart, Scott Koenig, Jennie P. Mather, Tony W. Liang, Claudia Fieger, Monica Licea, Jill R. Rillema, Jonathan C. Li, Ann N. Easton, Yan Chen, Tom Son, Yinhua Yang, Hua Li, Valentina Ciccarone, Steve Burke, Sergey Gorlatov, Wenjun Zhang, Ling Huang, Francine Z. Chen, Ralph F. Alderson, Deryk Loo
PDF file, 204KB, Panel A: Representative reactivity of anti-B7-H3 mAb BRCA84D with frozen tissue sections of prostate, breast, colon, lung, gastric and renal cancer. Panel B: Reactivity of anti-B7-H3 mAb BRCA69D on formalin-fixed paraffin embedded no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7653e82b56feaac91704e70391b9be55
https://doi.org/10.1158/1078-0432.22447004
https://doi.org/10.1158/1078-0432.22447004