Zobrazeno 1 - 10
of 132
pro vyhledávání: '"Sybren S. Wijmenga"'
Autor:
Agnieszka Smolinska, Lionel Blanchet, Leon Coulier, Kirsten A M Ampt, Theo Luider, Rogier Q Hintzen, Sybren S Wijmenga, Lutgarde M C Buydens
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38163 (2012)
BACKGROUND: In the last decade data fusion has become widespread in the field of metabolomics. Linear data fusion is performed most commonly. However, many data display non-linear parameter dependences. The linear methods are bound to fail in such si
Externí odkaz:
https://doaj.org/article/a505c42347ac4424ba9c1f069ddc3bc2
Publikováno v:
Progress in Nuclear Magnetic Resonance Spectroscopy, 96, 89-108
Progress in Nuclear Magnetic Resonance Spectroscopy, 96, pp. 89-108
Progress in Nuclear Magnetic Resonance Spectroscopy, 96, pp. 89-108
NMR is a powerful method for studying proteins and nucleic acids in solution. The study of nucleic acids by NMR is far more challenging than for proteins, which is mainly due to the limited number of building blocks and unfavorable spectral propertie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47835007f12440b80da252578b350239
https://doi.org/10.1016/j.pnmrs.2016.06.001
https://doi.org/10.1016/j.pnmrs.2016.06.001
Autor:
Bram J. A. van Weerdenburg, Martin C. Feiters, Nan Eshuis, Sybren S. Wijmenga, Floris P. J. T. Rutjes, Ruud L. E. G. Aspers, Marco Tessari
Publikováno v:
Journal of Magnetic Resonance, 265, 59-66
Journal of Magnetic Resonance, 265, pp. 59-66
Journal of Magnetic Resonance, 265, pp. 59-66
SABRE (Signal Amplification By Reversible Exchange) nuclear spin hyperpolarization method can provide strongly enhanced NMR signals as a result of the reversible association of small molecules with para-hydrogen (p-H2) at an iridium metal complex. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b90d5d5dc73be91938a69c47a83bb211
https://doi.org/10.1016/j.jmr.2016.01.012
https://doi.org/10.1016/j.jmr.2016.01.012
Autor:
Nan Eshuis, Niels K. J. Hermkens, Floris P. J. T. Rutjes, Sybren S. Wijmenga, Marco Tessari, Martin C. Feiters, Bram J. A. van Weerdenburg
Publikováno v:
Analytica Chimica Acta, 88, 3406-3412
Analytica Chimica Acta, 88, 6, pp. 3406-3412
Analytica Chimica Acta, 88, 6, pp. 3406-3412
When dealing with trace analysis of complex mixtures, NMR suffers from both low sensitivity and signal overlap. NMR chemosensing, in which the association between an analyte and a receptor is "signaled" by an NMR response, has been proposed as a valu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::075a5b818bf3d10e61efbcdf6b8b10a1
https://hdl.handle.net/2066/158671
https://hdl.handle.net/2066/158671
Autor:
Sybren S. Wijmenga, Martin C. Feiters, Niels K. J. Hermkens, Floris P. J. T. Rutjes, Marco Tessari
Publikováno v:
Journal of Magnetic Resonance, 276, 122-127
Journal of Magnetic Resonance, 276, pp. 122-127
Journal of Magnetic Resonance, 276, pp. 122-127
SABRE (Signal Amplification By Reversible Exchange) is a nuclear spin hyperpolarization technique based on the reversible concurrent binding of small molecules and para -hydrogen ( p -H 2 ) to an iridium metal complex in solution. At low magnetic fie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3635509002b9bbcbbbd2880334274b31
https://doi.org/10.1016/j.jmr.2017.01.011
https://doi.org/10.1016/j.jmr.2017.01.011
Autor:
Nan Eshuis, Marco Tessari, Martin C. Feiters, Bram J. A. van Weerdenburg, Sybren S. Wijmenga, Floris P. J. T. Rutjes
Publikováno v:
Angewandte Chemie. International Edition, 54, 5, pp. 1481-1484
Angewandte Chemie. International Edition, 54, 1481-1484
Angewandte Chemie. International Edition, 54, 1481-1484
Signal amplification by reversible exchange (SABRE) is an emerging nuclear spin hyperpolarization technique that strongly enhances NMR signals of small molecules in solution. However, such signal enhancements have never been exploited for concentrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e8649fb189f7fc3fe2af81a0cdecbb9
https://doi.org/10.1002/ange.201409795
https://doi.org/10.1002/ange.201409795
Publikováno v:
Magnetic Resonance in Medicine. 73:459-468
Purpose Accurate metabolite and protein quantification in blood plasma and other body fluids from one single NMR measurement, allowing for improved quantitative metabolic profiling and better assessment of metabolite-protein interactions. Theory and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58d4b3fa7f903b49eb739b2ab76661b3
https://doi.org/10.1002/mrm.25178
https://doi.org/10.1002/mrm.25178
Autor:
Sybren S. Wijmenga, Ruud L. E. G. Aspers, Jenny I. Halff, René van Elk, Reka A. Otvos, Andreas W. Ehlers, Richard J. Lewis, Ferry Heus, Wilfried M. A. Niessen, Sébastien Dutertre, Jeroen Kool, August B. Smit
Publikováno v:
Biology
Biology, MDPI 2014, 3 (1), pp.139-156. ⟨10.3390/biology3010139⟩
Biology, 3, 1, pp. 139-156
Heus, F A H, Otvos, R A, Aspers, R L E G, van Elk, R, Halff, J I, Ehlers, A W, Duterte, S, Lewis, R J, Wijmenga, S, Smit, A B, Niessen, W M A & Kool, J 2014, ' Miniaturized bioactivity assessment coupled to mass spectrometry for guided purification of bioactives from toad and cone snail ', Biology, vol. 3, pp. 139-156 . https://doi.org/10.3390/biology3010139
Biology, 3, 139-156. Multidisciplinary Digital Publishing Institute (MDPI)
Biology; Volume 3; Issue 1; Pages: 139-156
Biology, 3, 139-156
Biology, Vol 3, Iss 1, Pp 139-156 (2014)
Biology, MDPI 2014, 3 (1), pp.139-156. ⟨10.3390/biology3010139⟩
Biology, 3, 1, pp. 139-156
Heus, F A H, Otvos, R A, Aspers, R L E G, van Elk, R, Halff, J I, Ehlers, A W, Duterte, S, Lewis, R J, Wijmenga, S, Smit, A B, Niessen, W M A & Kool, J 2014, ' Miniaturized bioactivity assessment coupled to mass spectrometry for guided purification of bioactives from toad and cone snail ', Biology, vol. 3, pp. 139-156 . https://doi.org/10.3390/biology3010139
Biology, 3, 139-156. Multidisciplinary Digital Publishing Institute (MDPI)
Biology; Volume 3; Issue 1; Pages: 139-156
Biology, 3, 139-156
Biology, Vol 3, Iss 1, Pp 139-156 (2014)
A nano-flow high-resolution screening platform, featuring a parallel chip-based microfluidic bioassay and mass spectrometry coupled to nano-liquid chromatography, was applied to screen animal venoms for nicotinic acetylcholine receptor like (nAChR) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca403a753e3c96642a854645b6c89308
https://doi.org/10.3390/biology3010139
https://doi.org/10.3390/biology3010139
Autor:
Frank H. T. Nelissen, J.L. Wu, M.I. Su, M.C.C. Chen, J.F. Doreleijers, Tsai, Sybren S. Wijmenga, Sandeep Kumar, L.H. Lim, Chung-Feng Wang, Wen-Jin Wu
Publikováno v:
Journal of the American Chemical Society, 136, 13, pp. 4927-4937
Journal of the American Chemical Society, 136, 4927-4937
Journal of the American Chemical Society, 136, 4927-4937
A dogma for DNA polymerase catalysis is that the enzyme binds DNA first, followed by MgdNTP. This mechanism contributes to the selection of correct dNTP by Watson-Crick base pairing, but it cannot explain how low-fidelity DNA polymerases overcome Wat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe4e3161301d9d7a4fa725b172f86108
https://hdl.handle.net/2066/128384
https://hdl.handle.net/2066/128384
Publikováno v:
Journal of Magnetic Resonance, 231, 79-89
Journal of Magnetic Resonance, 231, pp. 79-89
Journal of Magnetic Resonance, 231, pp. 79-89
The use of fluorine in molecules obtained from chemical synthesis has become increasingly important within the pharmaceutical and agricultural industry. NMR characterization of these compounds is of great value with respect to their structure elucida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e54befd0eaa82ebbf79d349141bce4e
https://doi.org/10.1016/j.jmr.2013.03.008
https://doi.org/10.1016/j.jmr.2013.03.008