Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Sybren L. N. Maas"'
Autor:
Mark P. van Opijnen, Marike L. D. Broekman, Filip Y. F. de Vos, Edwin Cuppen, Jacobus J. M. van der Hoeven, Myra E. van Linde, Annette Compter, Laurens V. Beerepoot, Martin J. van den Bent, Maaike J. Vos, Helle-Brit Fiebrich, Johan A. F. Koekkoek, Ann Hoeben, Kuan H. Kho, Chantal M. L. Driessen, Hanne-Rinck Jeltema, Pierre A. J. T. Robe, Sybren L. N. Maas
Publikováno v:
BMC Medical Genomics, Vol 15, Iss 1, Pp 1-8 (2022)
Abstract Background Glioblastoma (GBM), the most common glial primary brain tumour, is without exception lethal. Every year approximately 600 patients are diagnosed with this heterogeneous disease in The Netherlands. Despite neurosurgery, chemo -and
Externí odkaz:
https://doaj.org/article/cfe094ec48aa400ca623264ad921e979
Autor:
Sybren L. N. Maas, Erik R. Abels, Lieke L. Van De Haar, Xuan Zhang, Liza Morsett, Srinjoy Sil, Joana Guedes, Pritha Sen, Shilpa Prabhakar, Suzanne E. Hickman, Charles P. Lai, David T. Ting, Xandra O. Breakefield, Marike L. D. Broekman, Joseph El Khoury
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-18 (2020)
Abstract Background Glioblastomas are the most common and lethal primary brain tumors. Microglia, the resident immune cells of the brain, survey their environment and respond to pathogens, toxins, and tumors. Glioblastoma cells communicate with micro
Externí odkaz:
https://doaj.org/article/b9621698f61b420098d1d9686658007c
Autor:
Thomas S. van Solinge, Erik R. Abels, Lieke L. van de Haar, Killian S. Hanlon, Sybren L. N. Maas, Rosalie Schnoor, Jeroen de Vrij, Xandra O. Breakefield, Marike L. D. Broekman
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
Introduction: Glioma cells exert influence over the tumor-microenvironment in part through the release of extracellular vesicles (EVs), membrane-enclosed structures containing proteins, lipids, and RNAs. In this study, we evaluated the function of Ra
Externí odkaz:
https://doaj.org/article/b0557c179e79404c881d03d2332a9977
Autor:
Erik R. Abels, Lisa Nieland, Suzanne Hickman, Marike L. D. Broekman, Joseph El Khoury, Sybren L. N. Maas
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 3, p 1495 (2021)
One of the essential functions of microglia is to continuously sense changes in their environment and adapt to those changes. For this purpose, they use a set of genes termed the sensome. This sensome is comprised of the most abundantly expressed rec
Externí odkaz:
https://doaj.org/article/c9ee62ce17de4db48c7551894549f8b7
Autor:
Robert Vogel, Frank A. W. Coumans, Raluca G. Maltesen, Anita N. Böing, Katherine E. Bonnington, Marike L. Broekman, Murray F. Broom, Edit I. Buzás, Gunna Christiansen, Najat Hajji, Søren R. Kristensen, Meta J. Kuehn, Sigrid M. Lund, Sybren L. N. Maas, Rienk Nieuwland, Xabier Osteikoetxea, Rosalie Schnoor, Benjamin J. Scicluna, Mitch Shambrook, Jeroen de Vrij, Stephen I. Mann, Andrew F. Hill, Shona Pedersen
Publikováno v:
Journal of Extracellular Vesicles, Vol 5, Iss 0, Pp 1-13 (2016)
Background: Understanding the pathogenic role of extracellular vesicles (EVs) in disease and their potential diagnostic and therapeutic utility is extremely reliant on in-depth quantification, measurement and identification of EV sub-populations. Qua
Externí odkaz:
https://doaj.org/article/456e048ddbcd4679b521f6fe03db04e9
Autor:
Bogdan Mateescu, Emma J. K. Kowal, Bas W. M. van Balkom, Sabine Bartel, Suvendra N. Bhattacharyya, Edit I. Buzás, Amy H. Buck, Paola de Candia, Franklin W. N. Chow, Saumya Das, Tom A. P. Driedonks, Lola Fernández-Messina, Franziska Haderk, Andrew F. Hill, Jennifer C. Jones, Kendall R. Van Keuren-Jensen, Charles P. Lai, Cecilia Lässer, Italia di Liegro, Taral R. Lunavat, Magdalena J. Lorenowicz, Sybren L. N. Maas, Imre Mäger, Maria Mittelbrunn, Stefan Momma, Kamalika Mukherjee, Muhammad Nawaz, D. Michiel Pegtel, Michael W. Pfaffl, Raymond M. Schiffelers, Hidetoshi Tahara, Clotilde Théry, Juan Pablo Tosar, Marca H. M. Wauben, Kenneth W. Witwer, Esther N. M. Nolte-‘t Hoen
Publikováno v:
Journal of Extracellular Vesicles, Vol 6, Iss 1 (2017)
The release of RNA-containing extracellular vesicles (EV) into the extracellular milieu has been demonstrated in a multitude of different in vitro cell systems and in a variety of body fluids. RNA-containing EV are in the limelight for their capacity
Externí odkaz:
https://doaj.org/article/6e00891f04814bb48656593b08283b8f
Autor:
Maximilian Y Deng, Felix Hinz, Sybren L N Maas, Günes Anil, Philipp Sievers, Cristina Conde-Lopez, Jonathan Lischalk, Sophie Rauh, Tanja Eichkorn, Sebastian Regnery, Lukas Bauer, Thomas Held, Eva Meixner, Kristin Lang, Juliane Hörner-Rieber, Klaus Herfarth, David Jones, Stefan M Pfister, Christine Jungk, Andreas Unterberg, Wolfgang Wick, Andreas von Deimling, Jürgen Debus, Felix Sahm, Laila König
Publikováno v:
Neuro-Oncology Advances.
Background The current CNS WHO classification of brain tumors distinguishes three malignancy grades in meningiomas, with increasing risk of recurrence from CNS WHO grade 1 to 3. Radiotherapy is recommended by current EANO guidelines for patients not
Autor:
Hildegard Dohmen, Hans-Georg Wirsching, Andreas von Deimling, Marco Stein, John G. Golfinos, Thomas Hielscher, Annika K. Wefers, Jens Schittenhelm, Fay E. A. Greenway, Areeba Patel, David T.W. Jones, Christian Mawrin, Chandra N. Sen, Elisabeth J. Rushing, Katrin Lamszus, Christine Jungk, Christina Blume, Anna S. Berghoff, Annekathrin Reinhardt, Jürgen Hench, Peter Baumgarten, Martin Sill, Till Acker, Daniel Schrimpf, Damian Stichel, Wolfgang Wick, David E. Reuss, Matija Snuderl, Miriam Ratliff, Marian Christoph Neidert, Michael Platten, Leslie R. Bridges, Sybren L. N. Maas, Abigail K. Suwala, Manfred Westphal, Stefan M. Pfister, Helin Dogan, Guido Reifenberger, Patrick N. Harter, Zane Jaunmuktane, Gerhard Jungwirth, Conor Grady, Severina Leu, Felix Sahm, Melanie Bewerunge-Hudler, Andreas Unterberg, Philipp Sievers, Nima Etminan, Michael Weller, Ralf Ketter, Jonathan Serrano, Matthias Preusser, Sebastian Brandner, Philipp Euskirchen, Christel Herold-Mende, Franz Ricklefs, Timothy L. Jones, Kenneth Aldape, Stephan Frank, Daniel Hänggi
Publikováno v:
Journal of Clinical Oncology. 39:3839-3852
PURPOSE Meningiomas are the most frequent primary intracranial tumors. Patient outcome varies widely from benign to highly aggressive, ultimately fatal courses. Reliable identification of risk of progression for individual patients is of pivotal impo
Autor:
Thomas Hielscher, Martin Sill, Philipp Sievers, Damian Stichel, Sebastian Brandner, David T. W. Jones, Andreas von Deimling, Felix Sahm, Sybren L. N. Maas
Publikováno v:
Brain Pathology. WILEY
Brain Pathology
Brain Pathology, 33(3):e13132. Wiley-Blackwell
Brain Pathology
Brain Pathology, 33(3):e13132. Wiley-Blackwell
Risk prediction for meningioma tumors was until recently almost exclusively based on morphological features of the tumor. To improve risk prediction, multiple models have been established that incorporate morphological and molecular features for an i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83f65dfe46ee3ddbb9d1863478e53872
http://hdl.handle.net/1887/3563698
http://hdl.handle.net/1887/3563698
Autor:
Ralf Ketter, Thomas Hielscher, Andreas Unterberg, Jürgen Hench, Peter Baumgarten, Matija Snuderl, Elizabeth Rushing, Martin Sill, Sebastian Brandner, Philipp Euskirchen, Stephan Frank, Marco Stein, Kenneth Aldape, Nima Etminan, Felix Sahm, Marian Christoph Neidert, Christian Mawrin, Michael Platten, Zane Jaunmuktane, Franz Ricklefs, Andreas von Deimling, Stefan M. Pfister, Severina Leu, David R. Jones, Patrick N. Harter, Manfred Westphal, Christine Jungk, Guido Reifenberger, Conor Grady, Till Acker, Miriam Ratliff, Matthias Preusser, Hans-Georg Wirsching, Sybren L. N. Maas, Anna S. Berghoff, Daniel Hänggi, Melanie Bewerunge-Hudler, Damian Stichel, Katrin Lamszus, Michael Weller, Jonathan Serrano, Jens Schittenhelm, Daniel Schrimpf, Philipp Sievers, Wolfgang Wick, David E. Reuss, Chandra N. Sen, John G. Golfinos, Hildegard Dohmen
Publikováno v:
Neuro Oncol
PURPOSE Meningiomas are the most frequent primary intracranial tumors. Patient outcome varies widely from cases with benign to highly aggressive, ultimately fatal courses. Reliable identification of risk of progression for the individual patient is o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9fb1498107c9f58cf26949b32033263
https://europepmc.org/articles/PMC8598891/
https://europepmc.org/articles/PMC8598891/