Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Sybille Muller"'
Autor:
Michael Piatak, Diane Waterman, John V. Carlis, Stefan E. Pambuccian, R. Keith Reeves, Cavan S. Reilly, Michael D. Alpert, Ming Zeng, Qingsheng Li, Dennis R. Burton, Mary Zupancic, Ashley T. Haase, Katherine Masek-Hammerman, Liang Shang, Jeffrey D. Lifson, Heinz Kohler, R. Paul Johnson, Pamela J. Skinner, Peter J. Southern, James E. Voss, Anthony J. Smith, Stephen W. Wietgrefe, James E. Robinson, Sybille Muller, Cynthia A. Derdeyn, Lijie Duan, David T. Evans
Publikováno v:
The Journal of Immunology. 193:3113-3125
We sought design principles for a vaccine to prevent HIV transmission to women by identifying correlates of protection conferred by a highly effective live attenuated SIV vaccine in the rhesus macaque animal model. We show that SIVmac239Δnef vaccina
Publikováno v:
Frontiers in Oncology, Vol 6 (2016)
Frontiers in Oncology
Frontiers in Oncology
In this review, we trace the concept and potential functional role of regulatory idiotypes in the immune response to human immunodeficiency virus type 1 (HIV-1), simian immunodeficiency virus, and hepatitis C virus (HCV). A major idiotype involved in
Publikováno v:
Drug Discovery Today. 10:1231-1236
Superantibody technology represents a method to enhance the potency and utility of monoclonal antibodies. The blueprint for superantibody technology is taken from rare naturally occurring superantibodies with unique sequence regions, conferring speci
Autor:
Sybille Muller
Publikováno v:
International Reviews of Immunology. 23:423-436
Lymphocyte clonal restriction is caused by priming the immune system with an antigen and has been referred to infectious disease study as "original antigenic sin" (OAS), described first for influenza by Francis. OAS is a dominant feature of a normal
Publikováno v:
International Reviews of Immunology. 23:369-381
This overview briefly summarizes the current status of global AIDS epidemic, especially pointing out how this pandemic looked in the last year of the second millennium. We also give a brief overview of the state of the art in development of AIDS vacc
Publikováno v:
Apoptosis. 8:631-637
Caspase 3 is critically involved in the pathway of apoptosis. We have conjugated a MTS-transport-peptide to monoclonal and polyclonal anti-caspase-3 antibodies to suppress Actinomycin D-induced apoptosis in human lymphoma T cells. The advantage of us
Autor:
Cavan S. Reilly, Lijie Duan, Heinz Kohler, Ashley T. Haase, Katherine Perkey, Peter J. Southern, Stephen W. Wietgrefe, Liang Shang, Anthony J. Smith, Qingsheng Li, Sybille Muller, John V. Carlis, R. Paul Johnson, James E. Robinson
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 193(6)
Principles to guide design of an effective vaccine against HIV are greatly needed, particularly to protect women in the pandemic’s epicenter in Africa. We have been seeking these principles by identifying correlates of the robust protection associa
Publikováno v:
Human vaccinesimmunotherapeutics. 9(7)
Antibodies (Abs) induced during infections with immunodeficiency viruses are subject to a form of original antigenic sin, termed repertoire freeze. This phenomenon encompasses conditions in which antigen (Ag)-specific B-cells and free Ab induced agai
Autor:
Frank Martiniuk, Feng Wu, Sybille Muller, Seth H. Pincus, Shaoan Fan, Kam-Meng Tchou-Wong, Heinz Kohler
Publikováno v:
World journal of biological chemistry. 1(5)
AIM: To evaluate the ability of anti-ricin A-chain antibodies, delivered intracellularly, to protect against ricin-induced cytotoxicity in RAW264.7 cells. METHODS: Anti-deglycosylated ricin A-chain antibody and RAC18 anti-ricin A-chain monoclonal ant
Autor:
Claude P. Muller, Veljko Veljkovic, Vladimir Perovic, Nevena Veljkovic, Sanja Glisic, Heinz Kohler, Sybille Muller
Publikováno v:
BMC Structural Biology, Vol 9, Iss 1, p 21 (2009)
BMC Structural Biology
BMC Structural Biology
Background Epidemics caused by highly pathogenic avian influenza virus (HPAIV) are a continuing threat to human health and to the world's economy. The development of approaches, which help to understand the significance of structural changes resultin