Výsledky vyhledávání - "Sybille Dr. Beier"

The progestational activity of different gestagens used for human contraception in the beagle bitch

Autor: Beate Kosub, B. Düsterberg, F. Haase, Walter Dr Elger, Sybille Dr. Beier

Publikováno v: Contraception. 20:533-548

In long-term studies chlormadinone acetate (CMA) and cyproterone acetate (CPA) have much more pronounced mammotropic effects in dogs than norethisterone acetate (NA) or levonorgestrel (LN). To evaluate gestagenic potency of these compounds in dogs as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5af45705371a8e66122e4fc310adef50
https://doi.org/10.1016/s0010-7824(79)80033-5

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Gestodene: A novel synthetic progestin — characterization of binding to receptor and serum proteins

Autor: K. Schmidt-Gollwitzer, W. Elger, Kunhard Pollow, Sybille Dr. Beier, Bernhard Manz, Hans-Jörg Grill, David Dr Henderson, M. Juchem

Publikováno v: Contraception. 40:325-341

Gestodene, 17α-ethinyl-13-ethyl-17β-hydroxy-4,15-gonadien-3-one, is a new orally active progestational agent, which is available for clinical use in oral contraceptives. The aim of the present study is to make a broad characterization of gestodene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7de451b32a6c7d19a251991d6b0ca4d5
https://doi.org/10.1016/0010-7824(89)90096-6

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Endometrial and myometrial effects of progesterone antagonists in pregnant guinea pigs

Autor: Walter Elger, Shi Shao Qing, Krzysztof Chwalisz, Sybille Dr. Beier, Marianne Fähnrich

Publikováno v: American Journal of Obstetrics and Gynecology. 157:1065-1074

Three anti progestogens of the RU 38.486 type, RU 38.486, ZK 98.734, and ZK 98.299, were studied at different stages of pregnancy in the guinea pig. Treatment starting on postconception day 4 completely prevented nidation; all three compounds had com

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a8278730e2b29734fbdd3021e767dad
https://doi.org/10.1016/s0002-9378(87)80134-5

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3H-ZK 98,734, a new 11β-aryl substituted antigestagen: Binding characteristics to receptor and serum proteins

Autor: Kunhard Pollow, Hans-Jörg Grill, M. Juchem, Sybille Dr. Beier, K. Schmidt-Gollwitzer, Bernhard Manz, W. Elger, David Dr Henderson

Publikováno v: Contraception. 40:213-232

Recently, in the laboratories of Schering in Germany a competitive progesterone antagonist, ZK 98,734, was synthetized, which is characterized by a similar antigestagenic activity as RU 38,486, synthezised by Roussel-Uclaf in France, as assessed by i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4f78b00a984133c296903ee297dcfae
https://doi.org/10.1016/0010-7824(89)90008-5

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Studies on the mechanisms of action of progesterone antagonists

Autor: Sybille Dr. Beier, S. H. Hasan, R. Rohde, David Dr Henderson, Walter Elger, Günter Neef, Krzysztof Chwalisz, Marianne Fähnrich

Publikováno v: Journal of steroid biochemistry. 25(5B)

Antigestagens of RU-38.486-type were investigated in different pregnancy models reflecting either "endometrial" or "myometrial" effects. All antigestagens were found effective inhibitors of nidation in guinea pigs. This was evidence for a role of emb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddf529872941410c833568b6503da21a
https://pubmed.ncbi.nlm.nih.gov/3543502

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