Výsledky vyhledávání - "Sybille Arnold"

Antibodies against cyclic citrullinated peptide are associated with the DRB1 shared epitope and predict joint erosion in rheumatoid arthritis

Autor: Christoph Baerwald, Sybille Arnold, Matthias Pierer, Sylke Kaltenhäuser, Holm Häntzschel, M. Kamprad, Ulf Wagner

Publikováno v: Rheumatology. 46:100-104

Objective To evaluate antibodies against cyclic citrullinated peptide (anti-CCP antibodies) for their predictive value for severe joint destruction in rheumatoid arthritis (RA) and to examine their relationship to shared epitope (SE)-positive DRB1 al

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60c5580a4e46c8a9518abd7cc1058bb8
https://doi.org/10.1093/rheumatology/kel052

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Clonal expansions in selected TCR BV families of rheumatoid arthritis patients are reduced by treatment with the TNFα inhibitors etanercept and infliximab

Autor: Christoph Baerwald, Sybille Arnold, Manuela Rossol, Matthias Pierer, Holm Häntzschel, Ulf Wagner, Sylke Kaltenhäuser

Publikováno v: Rheumatology international. 31(8)

Clonal expansions of autoreactive CD4+ T cells are frequently present in patients with rheumatoid arthritis (RA) and are stable over long periods of time. This study was undertaken to investigate the influence of anti-TNFα treatment on such clonal e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6851e5b30ba0ed4ee97c86575eda931f
https://pubmed.ncbi.nlm.nih.gov/20306048

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Negative association of the chemokine receptor CCR5 d32 polymorphism with systemic inflammatory response, extra-articular symptoms and joint erosion in rheumatoid arthritis

Autor: Manuela Rossol, Matthias Pierer, Gernot Keyßer, Christoph Baerwald, Harald Burkhardt, Ulf Wagner, Sybille Arnold

Publikováno v: Arthritis Research & Therapy

Introduction Chemokines and their receptors control immune cell migration during infections as well as in autoimmune responses. A 32 bp deletion in the gene of the chemokine receptor CCR5 confers protection against HIV infection, but has also been re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3f7f185fd186e841ff9c97b40f66769
http://publikationen.ub.uni-frankfurt.de/files/6717/ar2733.pdf

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Clonally expanded CD4+CD28null T cells in rheumatoid arthritis use distinct combinations of T cell receptor BV and BJ elements

Autor: Sybille Arnold, Holm Häntzschel, Matthias Pierer, Sylke Kaltenhäuser, Ulf Wagner, W. Seidel, Bernd Wilke

Publikováno v: European journal of immunology. 33(1)

Clonally expanded, autoreactive CD4(+)CD28(null) cells can be found in the peripheral blood of patients with rheumatoid arthritis and have been shown to be associated with severeextra-articular disease manifestations. We investigated the size of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::064f20ecccd70e3e7043c55b1292b41f
https://pubmed.ncbi.nlm.nih.gov/12594835

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Differences in B cell regulation in DRB1 shared epitope positive and negative rheumatoid arthritis

Autor: Sybille Arnold, Sylke Kaltenhäuser, Matthias Pierer, Ulf Wagner, Bernd Wilke, Holm Häntzschel

Publikováno v: Arthritis Research

Aim of the study was the analysis of systemic B cell activity and of the size of the B lymphocyte compartment in patients with rheumatoid arthritis (RA)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbfc61a97007c1e5a3208191494026c9
https://doi.org/10.1186/ar219

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HLA markers and prediction of clinical course and outcome in rheumatoid arthritis

Autor: Heidemarie Sauer, Sybille Arnold, Ralf Wassmuth, Sylke Kaltenhäuser, W. Seidel, Joachim R. Kalden, Ulf Wagner, Holm Häntzschel

Publikováno v: Arthritis and rheumatism. 40(2)

Objective. To evaluate HLA markers as early prognostic factors for disease severity in rheumatoid arthritis (RA). Methods. HLA genotyping was carried out in a retrospective analysis of 66 RA patients and in a prospective study of 55 RA patients and 8

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbc005d916114d9b9e1ab919f30ed9fb
https://pubmed.ncbi.nlm.nih.gov/9041946

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[Untitled]

Autor: Ulf Wagner, Sybille Arnold, Matthias Pierer, Christoph Baerwald, Sylke Kaltenhäuser, Matthias Wahle, Holm Häntzschel

Publikováno v: Arthritis Research & Therapy. 8:R75

The functional single-nucleotide polymorphism (SNP) of the gene PTPN22 is a susceptibility locus for rheumatoid arthritis (RA). The study presented here describes the association of the PTPN22 1858T allele with RA in a German patient cohort; 390 pati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fd9685512b6ceb82e63fc6ccb5f92422
https://doi.org/10.1186/ar1945

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[Untitled]

Autor: Sybille Arnold, Matthias Pierer, Holm Häntzschel, Sylke Kaltenhäuser, Ulf Wagner, Bernd Wilke

Publikováno v: Arthritis Research. 4:R1

The influence of HLA DRB1 alleles on B-cell homeostasis was analyzed in 164 patients with rheumatoid arthritis (RA). The percentages of CD19+ B lymphocytes determined in the peripheral circulation of 94 retrospectively recruited RA patients followed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::605486354f5410cd59bf27570083098f
https://doi.org/10.1186/ar420

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