Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sybil C. L. Hrstka"'
Autor:
Ashley A. Krull, Deborah O. Setter, Tania F. Gendron, Sybil C. L. Hrstka, Michael J. Polzin, Joseph Hart, Amel Dudakovic, Nicolas N. Madigan, Allan B. Dietz, Anthony J. Windebank, Andre J. van Wijnen, Nathan P. Staff
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-14 (2021)
Abstract Background Mesenchymal stromal cells (MSCs) have been studied with increasing intensity as clinicians and researchers strive to understand the ability of MSCs to modulate disease progression and promote tissue regeneration. As MSCs are used
Externí odkaz:
https://doaj.org/article/47692b6a9c6541b9a0f6a8f7dadecf99
Autor:
Tania F. Gendron, Amel Dudakovic, Ashley A. Krull, Allan B. Dietz, Andre J. van Wijnen, Deborah O. Setter, Nathan P. Staff, Joseph Hart, Michael J. Polzin, Nicolas N. Madigan, Anthony J. Windebank, Sybil C. L. Hrstka
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-14 (2021)
Stem Cell Research & Therapy
Stem Cell Research & Therapy
Background Mesenchymal stromal cells (MSCs) have been studied with increasing intensity as clinicians and researchers strive to understand the ability of MSCs to modulate disease progression and promote tissue regeneration. As MSCs are used for diver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::377abe440d30ac67847202330bc20d7f
https://doaj.org/article/47692b6a9c6541b9a0f6a8f7dadecf99
https://doaj.org/article/47692b6a9c6541b9a0f6a8f7dadecf99
Autor:
Raymond A. Moore, Jon P. Klein, Nathan P. Staff, Busranur Agac, Sybil C. L. Hrstka, Isabella Schneider, Bhavya Narapureddy, Soneela Ankam, Ronald F. Hrstka, Surendra Dasari
Publikováno v:
Exp Neurol
The neurotoxic effects of the chemotherapeutic agent bortezomib on dorsal root ganglia sensory neurons are well documented, yet the mechanistic underpinnings that govern these cellular processes remain incompletely understood. In this study, system-w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::747d4c5d024632b8818c5a2e835ce74c
https://pubmed.ncbi.nlm.nih.gov/33129842
https://pubmed.ncbi.nlm.nih.gov/33129842
Autor:
Timothy J. Nelson, Frank J. Secreto, Alyson J. Smith, Bonnie K. Arendt, Sybil C. L. Hrstka, Ester Perales-Clemente, Emma B. Brandt, Elizabeth S. Bruinsma, Xing Li, Gresin Hawse, Saji Oommen, Dennis A. Wigle
Publikováno v:
Stem Cells Translational Medicine
Human induced pluripotent stem cells (hiPSC) hold great promise in diagnostic and therapeutic applications. However, translation of hiPSC technology depends upon a means of assessing hiPSC quality that is quantitative, high-throughput, and can deciph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0d8d1987156c9fa8e03ceea4491f669
http://europepmc.org/articles/PMC6430057
http://europepmc.org/articles/PMC6430057
Autor:
Jessica Edwards, Timothy J. Nelson, Andre Terzic, Xing Li, Saji Oommen, Santiago Reyes, Saranya P. Wyles, Sybil C. L. Hrstka, Timothy M. Olson, Rosanna Beraldi
Publikováno v:
Human Molecular Genetics. 25:254-265
Dilated cardiomyopathy (DCM) is a leading cause of heart failure. In families with autosomal-dominant DCM, heterozygous missense mutations were identified in RNA-binding motif protein 20 (RBM20), a spliceosome protein induced during early cardiogenes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae14622645b6cd4f5615e1731ca0e8c5
https://doi.org/10.1093/hmg/ddv468
https://doi.org/10.1093/hmg/ddv468
Autor:
Sybil C. L. Hrstka, Ester Perales-Clemente, Clifford D.L. Folmes, Almudena Martinez-Fernandez, Timothy J. Nelson, Amber McDonald, Xing Li, Carmen Perez-Terzic, Andre Terzic, Devin Oglesbee
Publikováno v:
Stem Cells. 31:1298-1308
Mitochondrial diseases display pathological phenotypes according to the mixture of mutant versus wild-type mitochondrial DNA (mtDNA), known as heteroplasmy. We herein examined the impact of nuclear reprogramming and clonal isolation of induced plurip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c015808bcc202a00dc01e8aae1f136a
https://doi.org/10.1002/stem.1389
https://doi.org/10.1002/stem.1389
Autor:
Sybil C. L. Hrstka, Andre Terzic, Timothy J. Nelson, Santiago Reyes, Saranya P. Wyles, Timothy M. Olson
Publikováno v:
Clinical and Translational Science
For inherited cardiomyopathies, abnormal sensitivity to intracellular calcium (Ca(2+) ), incurred from genetic mutations, initiates subsequent molecular events leading to pathological remodeling. Here, we characterized the effect of β-adrenergic str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aef4dcd150bce4d23b0657390d4e195
https://pubmed.ncbi.nlm.nih.gov/27105042
https://pubmed.ncbi.nlm.nih.gov/27105042
Autor:
Sybil C. L. Hrstka, Timothy M. Olson, Megan M. O’Byrne, Timothy J. Nelson, Mariza de Andrade, Patrick W. O'Leary, Jeanne L. Theis, Jared M. Evans
Publikováno v:
Human genetics. 134(9)
Hypoplastic left heart syndrome (HLHS) is a severe congenital heart defect (CHD) that necessitates staged, single ventricle surgical palliation. An increased frequency of bicuspid aortic valve (BAV) has been observed among relatives. We postulated nu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d0b16b7663400d7dd1a9ddfb12ad425
https://pubmed.ncbi.nlm.nih.gov/26164125
https://pubmed.ncbi.nlm.nih.gov/26164125
Autor:
Sybil C. L. Hrstka, Andre Terzic, Timothy M. Olson, Saranya P. Wyles, Xing Li, Jean Pierre A. Kocher, Timothy J. Nelson
Publikováno v:
BMC Bioinformatics
Background Induced pluripotent stem cells (iPSCs) derived from dilated cardiomyopathy (DCM) patients offer an unprecedented platform for in vitro disease modeling[1]. Time course transcriptome analysis on the differentiation process from iPSCs to bea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c64e53eb3c8c4059488cf5e8bb7b21a2
http://europepmc.org/articles/PMC4625215
http://europepmc.org/articles/PMC4625215