Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Swetha Vasudevan"'
Autor:
Lisa Uechi, Swetha Vasudevan, Daniela Vilenski, Sergio Branciamore, David Frankhouser, Denis O’Meally, Soheil Meshinchi, Guido Marcucci, Ya-Huei Kuo, Russell Rockne, Nataly Kravchenko-Balasha
Publikováno v:
npj Systems Biology and Applications, Vol 10, Iss 1, Pp 1-10 (2024)
Abstract Acute myeloid leukemia (AML) is prevalent in both adult and pediatric patients. Despite advances in patient categorization, the heterogeneity of AML remains a challenge. Recent studies have explored the use of gene expression data to enhance
Externí odkaz:
https://doaj.org/article/a23d4049946443e3bb7e7c33fa68dc28
Autor:
Reem Kamal Aldwaik, Denen Shian, Roshina Thapa, Swetha Vasudevan, Mimi Abo-Ayoub Ashqar, Eli Reich, Nataly Kravchenko-Balasha, Michael Klutstein
Publikováno v:
Translational Oncology, Vol 34, Iss , Pp 101703- (2023)
Cancer cells have an altered transcriptome, which contributes to their abnormal behavior. Many tumors have high levels of kinetochore genes, which play important roles in genome stability. This overexpression could be utilized to destabilize cancer c
Externí odkaz:
https://doaj.org/article/74e799c72c684143a4f4e7f30fe9babf
Autor:
Heba Alkhatib, Ariel M. Rubinstein, Swetha Vasudevan, Efrat Flashner-Abramson, Shira Stefansky, Sangita Roy Chowdhury, Solomon Oguche, Tamar Peretz-Yablonsky, Avital Granit, Zvi Granot, Ittai Ben-Porath, Kim Sheva, Jon Feldman, Noa E. Cohen, Amichay Meirovitz, Nataly Kravchenko-Balasha
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-17 (2022)
Abstract Background Drug resistance continues to be a major limiting factor across diverse anti-cancer therapies. Contributing to the complexity of this challenge is cancer plasticity, in which one cancer subtype switches to another in response to tr
Externí odkaz:
https://doaj.org/article/1bfb8d0fe62b40729734ee0a48f29698
Autor:
Shay Sharon, Thomas Duhen, Shelly Bambina, Jason Baird, Rom Leidner, Bryan Bell, Nardy Casap, Marka Crittenden, Swetha Vasudevan, Maria Jubran, Nataly Kravchenko-Balasha, Michael Gough
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Patients exhibit distinct responses to immunotherapies that are thought to be linked to their tumor immune environment. However, wide variations in outcomes are also observed in patients with matched baseline tumor environments, indicating that the b
Externí odkaz:
https://doaj.org/article/73dcc246a62349f8a41e6c4a86795fc2
Autor:
Hila Dagan, Efrat Flashner-Abramson, Swetha Vasudevan, Maria R. Jubran, Ehud Cohen, Nataly Kravchenko-Balasha
Publikováno v:
Biomolecules, Vol 10, Iss 4, p 503 (2020)
Despite huge investments and major efforts to develop remedies for Alzheimer’s disease (AD) in the past decades, AD remains incurable. While evidence for molecular and phenotypic variability in AD have been accumulating, AD research still heavily r
Externí odkaz:
https://doaj.org/article/3347ace34e9040b7baaed462cc8139a2
Autor:
Maria R. Jubran, Daniela Vilenski, Efrat Flashner-Abramson, Efraim Shnaider, Swetha Vasudevan, Ariel M. Rubinstein, Amichay Meirovitz, Shay Sharon, David Polak, Nataly Kravchenko-Balasha
Publikováno v:
Theranostics. 12:1204-1219
Therapeutic strategies for advanced head and neck squamous carcinoma (HNSCC) consist of multimodal treatment, including Epidermal Growth Factor Receptor (EGFR) inhibition, immune-checkpoint inhibition, and radio (chemo) therapy. Although over 90% of
Autor:
H. Jemmy Christy, Swetha Vasudevan, S. Sudha, Mahmoud Kandeel, Kumaran Subramanian, S. R. Pugazhvendan, P. Ronald Ross, null Velmurugan
Publikováno v:
BioMed research international. 2022
Streptomyces is amongst the most amenable genera for biotechnological applications, and it is extensively used as a scaffold for drug development. One of the most effective therapeutic applications in the treatment of cancer is targeted therapy. Smal
Autor:
Heba Alkhatib, Ibukun Adesoji Adejumobi, Ariel Rubinstein, Sangita Roy Chowdhury, Swetha Vasudevan, Shira Stefansky, Nataly Kravchenko-Balasha
Publikováno v:
Cancers, Vol 13, Iss 5009, p 5009 (2021)
Cancers
Volume 13
Issue 19
Cancers
Volume 13
Issue 19
Simple Summary Patients with Triple Negative Breast Cancer (TNBC) have a poor prognosis due to high inter-tumor heterogeneity and absence of effective targeted treatments. Through quantification of ongoing processes in each individual with TNBC, we p
Autor:
D Vilenski, Swetha Vasudevan, Heba Alkhatib, Ibukun Adesoji Adejumobi, Shira Stefansky, Nataly Kravchenko-Balasha, Efrat Flashner-Abramson, A M Rubinstein, Sangita Roy Chowdhury
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-13 (2021)
BRAFV600E melanoma patients, despite initially responding to the clinically prescribed anti-BRAFV600E therapy, often relapse, and their tumors develop drug resistance. While it is widely accepted that these tumors are originally driven by the BRAFV60
Autor:
Efrat Flashner-Abramson, Swetha Vasudevan, Ibukun Adesoji Adejumobi, Amir Sonnenblick, Nataly Kravchenko-Balasha
Publikováno v:
Theranostics
The past years have witnessed a rapid increase in the amount of large-scale tumor datasets. The challenge has now become to find a way to obtain useful information from these masses of data that will allow to determine which combination of FDA-approv