Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Swetha Rathan"'
Autor:
Helen O. McCarthy, Daniel J. Kelly, Tomas Gonzalez-Fernandez, Nicholas Dunne, Pierluca Pitacco, Christopher Hobbs, Gráinne M. Cunniffe, Swetha Rathan, Fiona E. Freeman, Fergal J. O'Brien, Valeria Nicolosi
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 301
The regeneration of complex tissues and organs remains a major clinical challenge. With a view towards bioprinting such tissues, we developed a new class of pore-forming bioink to spatially and temporally control the presentation of therapeutic genes
Autor:
Casey Jane Ankeny, Ruth Fogg, Ajit P. Yoganathan, Juan C. Briceño, Diana M. Sánchez-Palencia, Swetha Rathan
Publikováno v:
Journal of Tissue Engineering and Regenerative Medicine. 11:1427-1434
In small intestinal submucosa (SIS) scaffolds for functional tissue engineering, the impact of scaffold fabrication parameters on cellular response and tissue regeneration may relate to the mechanotransductory properties of the final arrangement of c
Autor:
Swetha Rathan, Léa Dejob, Daniel J. Kelly, Rossana Schipani, Benjamin Haffner, Matthias E. Möbius
Publikováno v:
Advanced Healthcare Materials
Focal articular cartilage (AC) defects, if left untreated, can lead to debilitating diseases such as osteoarthritis. While several tissue engineering strategies have been developed to promote cartilage regeneration, it is still challenging to generat
Publikováno v:
Annals of Biomedical Engineering. 41:1331-1346
The aortic valve (AV) experiences a complex mechanical environment, which includes tension, flexure, pressure, and shear stress forces due to blood flow during each cardiac cycle. This mechanical environment regulates AV tissue structure by constantl
Autor:
Jack M. Heath, Swetha Rathan, Casey Jane Ankeny, Sandeep Kumar, Ajit P. Yoganathan, Hanjoong Jo, Sivakkumar Arjunon, Zannatul Ferdous, Joan Fernandez Esmerats, Robert M. Nerem
Publikováno v:
Scientific Reports
Aortic valve (AV) calcification is an inflammation driven process that occurs preferentially in the fibrosa. To explore the underlying mechanisms, we investigated if key microRNAs (miRNA) in the AV are differentially expressed due to disturbed blood
Autor:
Diana, Sánchez-Palencia, Swetha, Rathan, Casey J, Ankeny, Ruth, Fogg, Juan C, Briceño, Ajit P, Yoganathan
Publikováno v:
Journal of tissue engineering and regenerative medicine. 11(5)
In small intestinal submucosa (SIS) scaffolds for functional tissue engineering, the impact of scaffold fabrication parameters on cellular response and tissue regeneration may relate to the mechanotransductory properties of the final arrangement of c
Autor:
Sivakkumar Arjunon, Harika Gorti, Anita Rajamani, Ajit P. Yoganathan, Swetha Rathan, Hanjoong Jo
Publikováno v:
5th Biennial Conference on Heart Valve Biology and Tissue Engineering.
Aortic valve (AV) sclerosis is a degenerative disease and is one of the leading causes of mortality in elderly population. AV experiences various mechanical stimuli such as pressure, shear and flexure with differing magnitudes on either sides of AV (
Publikováno v:
5th Biennial Conference on Heart Valve Biology and Tissue Engineering.
A variety of ex vivo bioreactors have been developed to study the mechanobiology of valves and valve substitutes. Especially, bioreactors to mimic the individual mechanical stimuli (stretch, pressure and shear), have been well established. Going forw
Autor:
Choon Hwai Yap, Nikolay V. Vasilyev, Neelakantan Saikrishnan, Ajit P. Yoganathan, Gowthami Tamilselvan, Swetha Rathan
Publikováno v:
ASME 2011 Summer Bioengineering Conference, Parts A and B.
Aortic valve calcification is a degenerative disease with high prevalence, especially amongst the elderly, and is a major cause of morbidity and mortality. Ex vivo experiments has shown that aortic valve leaflets are sensitive to their mechanical env
Autor:
Sivakkumar Arjunon, Ajit P. Yoganathan, Choon Hwai Yap, Hanjoong Jo, Swetha Rathan, Elizabeth Morris
Publikováno v:
ASME 2011 Summer Bioengineering Conference, Parts A and B.
Aortic Valve (AV) calcification is a degenerative disease that results in AV sclerosis and is one of the major causes of death. AV is subjected to mechanical conditions such as fluid shear stress, transvalvular pressure and membrane tension1. Normal