Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Swetha Pendem"'
Autor:
Adrien Guillot, Marc Winkler, Milessa Silva Afonso, Abhishek Aggarwal, David Lopez, Hilmar Berger, Marlene S. Kohlhepp, Hanyang Liu, Burcin Özdirik, Johannes Eschrich, Jing Ma, Moritz Peiseler, Felix Heymann, Swetha Pendem, Sangeetha Mahadevan, Bin Gao, Lauri Diehl, Ruchi Gupta, Frank Tacke
Publikováno v:
Hepatology.
Autor:
Swetha Pendem, Igor Mikaelian, Sarani Ghoshal, Anna Zagorska, Archana Vijayakumar, Katie Walker, Bryan C. Fuchs, Robert Brockett, K. Liu, Bruno Marchand, David Lopez, David G. Breckenridge, Li Li, Ricardo Ramirez, Jamie Bates, Saritha Kusam, Dmytro Kornyeyev, Saili Yi, David Newstrom, David Hollenback
Publikováno v:
Journal of Hepatology. 73:896-905
Background & Aims Non-alcoholic steatohepatitis (NASH) is a chronic liver disease characterized by hepatic lipid accumulation, inflammation, and progressive fibrosis. Acetyl-CoA carboxylase (ACC) catalyzes the rate-limiting step of de novo lipogenesi
Autor:
David G. Breckenridge, Laurie A. Castonguay, Giuseppe A. Papalia, Swetha Pendem, Shawn S. Badal, Ford Hinojosa-Kirschenbaum, Gregory T. Notte, Sarah Wise, Michael V. Lee, Keith A. Koch, Agnes B. Fogo, Dorothy French, Britton Kenneth Corkey, Frank Y. Ma, Brian E. Schultz, Eric B. Lansdon, Melanie H. Wong, David J. Nikolic-Paterson, Tareq M Al-Tuhaifi, Theodore Sullivan, Michael Graupe, Haichun Yang, Erik Huntzicker, Grant R. Budas, John T. Liles
Publikováno v:
Journal of Clinical Investigation. 128:4485-4500
Oxidative stress is an underlying component of acute and chronic kidney disease. Apoptosis signal–regulating kinase 1 (ASK1) is a widely expressed redox-sensitive serine threonine kinase that activates p38 and c-Jun N-terminal kinase (JNK) mitogen-
Autor:
Stephen J. Wigmore, Kylie P. Matchett, Prakash Ramachandran, Thomas E. Hudson, Swetha Pendem, James Smith, Grant R. Budas, Sarah A. Teichmann, John R. Wilson-Kanamori, John C. Marioni, Neil C. Henderson, Simone Picelli, Jordan R. Portman, David G. Breckenridge, Anna Zagorska, Minnie M. Wu, Chris P. Ponting, Karolina Wallenborg, Ross Dobie, Ewen M Harrison, Damian J. Mole, Beth E. P. Henderson
Publikováno v:
Dobie, R, Wilson-Kanamori, J R, Henderson, B, Smith, J, Matchett, K, Portman, J, Wallenborg, K, Picelli, S, Zagórska, A, Pendem, S V, Hudson, T E, Wu, M M, Budas, G R, Breckenridge, D G, Harrison, E, Mole, D J, Wigmore, S J, Ramachandran, P, Ponting, C P, Teichmann, S A, Marioni, J C & Henderson, N C 2019, ' Single-Cell Transcriptomics Uncovers Zonation of Function in the Mesenchyme during Liver Fibrosis ', Cell Reports, vol. 29, no. 7, pp. 1832-1847.e8 . https://doi.org/10.1016/j.celrep.2019.10.024
Cell Reports
Cell Reports, Vol 29, Iss 7, Pp 1832-1847.e8 (2019)
Cell Reports
Cell Reports, Vol 29, Iss 7, Pp 1832-1847.e8 (2019)
Summary Iterative liver injury results in progressive fibrosis disrupting hepatic architecture, regeneration potential, and liver function. Hepatic stellate cells (HSCs) are a major source of pathological matrix during fibrosis and are thought to be