Adenovirus 36 infection and daycare starting age are associated with adiposity in children and adolescents

Autor: Ana Carolina Lobor Cancelier, Nikhil V. Dhurandhar, Swetha Peddibhotla, Richard L. Atkinson, Helena C.G. Silva, Daisson J. Trevisol, Fabiana Schuelter-Trevisol

Publikováno v: Jornal de Pediatria, Vol 97, Iss 4, Pp 420-425 (2021)

Objective: This study aimed to investigate human adenovirus 36 (Adv36) as an associated factor for adiposity in children and adolescents aged 9–12 years. Methods: This was a case-control study comparing overweight (cases) and eutrophic (controls) c

Externí odkaz: https://doaj.org/article/2a6086d97e6c4984a7df827cd89bb833

Adenovirus 36 infection and daycare starting age are associated with adiposity in children and adolescents

Autor: Daisson José Trevisol, Helena Caetano Gonçalves e Silva, Fabiana Schuelter-Trevisol, Swetha Peddibhotla, Ana Carolina Lobor Cancelier, Richard L. Atkinson, Nikhil V. Dhurandhar

Publikováno v: Jornal de Pediatria, Vol 97, Iss 4, Pp 420-425 (2021)
Jornal de Pediatria v.97 n.4 2021
Jornal de Pediatria
Sociedade Brasileira de Pediatria (SBP)
instacron:SBPE
Jornal de Pediatria, Volume: 97, Issue: 4, Pages: 420-425, Published: 18 AUG 2021

Objective This study aimed to investigate human adenovirus 36 (Adv36) as an associated factor for adiposity in children and adolescents aged 9–12 years. Methods This was a case-control study comparing overweight (cases) and eutrophic (controls) chi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16e2bf32815bff05eba7d97c883979e9
http://www.sciencedirect.com/science/article/pii/S002175572030200X

Nanoparticle-mediated in vitro delivery of E4orf1 to preadipocytes is a clinically relevant delivery system to improve glucose uptake

Autor: Shu Wang, Vijay Hegde, Shahjalal Hossain Khan, Nikhil V. Dhurandhar, Zahra Feizy, Swetha Peddibhotla

Publikováno v: International Journal of Obesity. 44:1607-1616

Impaired glycemic control is a common comorbidity of obesity. E4orf1(E4), an adenovirus-derived protein, reduces the activity of insulin receptor substrate (IRS), yet activates Akt and promotes the membrane translocation of GLUT4, resulting in better

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85f7a4aca05961022ceae5d545ab438a
https://doi.org/10.1038/s41366-020-0526-6

Abstract PO-132: Upregulated LYL1 promotes epithelial ovarian cancer (EOC) cell growth and metastasis

Autor: Damieanus Ochola, Shirisha Jonnalagadda, Swetha Peddibhotla, Tasmin Omy, Mark Reedy, Palle Komaraiah

Publikováno v: Cancer Epidemiology, Biomarkers & Prevention. 31:PO-132

Approximately 90% of ovarian cancer (OC) is Epithelial ovarian Cancer (EOC) subtype and claims ~15,000 lives in the United States annually, making it the deadliest reproductive cancer in women. There are few treatment options for EOC, amongst them in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::72d7b54cdd3dada2cf64aa2c485f115c
https://doi.org/10.1158/1538-7755.disp21-po-132

E4orf1 protein reduces the need for endogenous insulin

Autor: Swetha Peddibhotla, Vijay Hegde, Nikhil V. Dhurandhar, Akheruzzaman

Publikováno v: Nutrition & Diabetes
Nutrition & Diabetes, Vol 9, Iss 1, Pp 1-9 (2019)

Background E4orf1 protein derived from adenovirus-36 reduces glucose excursion in mice, and lowers endogenous insulin response, suggesting a reduced need for insulin. We tested if the E4orf1-mediated lowering of insulin response is due to increased t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ad75a8d22754f9745caa5623df6b237
http://europepmc.org/articles/PMC6534626