Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Swetha, Raman"'
Autor:
Jesi Charles, Latha Nedumaran, Swetha Raman, Elizabeth Vinod, Rajalakshmi Rajasegaran, Kamalakannan Vadivel, Anand Bhaskar, Sathya Subramani
Publikováno v:
Current Medical Issues, Vol 22, Iss 2, Pp 72-76 (2024)
Background: The major membrane currents responsible for sinoatrial (SA) rhythm generation are generally studied in isolated cardiac cells using electrophysiological tools. Such studies are resource and labor-intensive. Materials and Methods: Here, we
Externí odkaz:
https://doaj.org/article/57e84540474d4b5a92fa2ba222515d29
Autor:
Soosai Manickam Amirtham, Neetu Prince, Mangili Venkateswarulu, Iswar Chandra Mondal, Swetha Raman, Renu Raj, Elanchezhian Rajendran, Benjamin Jebaraj, Abirami Vaithiyalingam, Rajalakshmi Rajasegaran, Farhan Adam Mukadam, Anand Bhaskar, Subrata Ghosh, Jürgen Conrad, Uwe Beifuss, Sathya Subramani
Publikováno v:
ACS Omega, Vol 6, Iss 38, Pp 24553-24561 (2021)
Externí odkaz:
https://doaj.org/article/ce4b72e3a0ee4415b3a165d7af01459a
Autor:
Joan Seoane, Patricia Giblin, Jean-Philippe Julien, Judit Anido, Isabel Huber-Ruano, Johan Fransson, Dorothea Maetzel, Melissa Beilschmidt, Alexandre Bosch, Esther Lau, AJ Robert McGray, Almudena Neva-Alejo, Olga Egorova, Peter Bayliss, Swetha Raman, Alexandra Arias, Raffaella Iurlaro, Ester Bonfill-Teixidor, Robin M. Hallett
Supplementary Table 1: Description of TCGA derived mRNA expression cohorts used to examine LIF expression and associated transcript signaturesSupplementary Table 2: Transcription signatures used to identify biological processes and cell types correla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e876e51551f962bd9d5d74e20b1d20a
https://doi.org/10.1158/1078-0432.22482800
https://doi.org/10.1158/1078-0432.22482800
Autor:
Joan Seoane, Patricia Giblin, Jean-Philippe Julien, Judit Anido, Isabel Huber-Ruano, Johan Fransson, Dorothea Maetzel, Melissa Beilschmidt, Alexandre Bosch, Esther Lau, AJ Robert McGray, Almudena Neva-Alejo, Olga Egorova, Peter Bayliss, Swetha Raman, Alexandra Arias, Raffaella Iurlaro, Ester Bonfill-Teixidor, Robin M. Hallett
Supplementary Figure 1. Transcriptomic analysis demonstrates an enrichment of immunological pathways in high LIF tumors. Supplementary Figure 2. LIF transcripts are associated with a panel of immunosuppressive macrophage/myeloid signatures across hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27b4731b9846b1639fb87315ef90e1b6
https://doi.org/10.1158/1078-0432.22482803
https://doi.org/10.1158/1078-0432.22482803
Autor:
Joan Seoane, Patricia Giblin, Jean-Philippe Julien, Judit Anido, Isabel Huber-Ruano, Johan Fransson, Dorothea Maetzel, Melissa Beilschmidt, Alexandre Bosch, Esther Lau, AJ Robert McGray, Almudena Neva-Alejo, Olga Egorova, Peter Bayliss, Swetha Raman, Alexandra Arias, Raffaella Iurlaro, Ester Bonfill-Teixidor, Robin M. Hallett
Purpose:Leukemia inhibitory factor (LIF) is a multifunctional cytokine with numerous reported roles in cancer and is thought to drive tumor development and progression. Characterization of LIF and clinical-stage LIF inhibitors would increase our unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04b3ecc064e7d4473e93036075979191
https://doi.org/10.1158/1078-0432.c.6530999.v1
https://doi.org/10.1158/1078-0432.c.6530999.v1
Autor:
Jesi Charles, Latha Nedumaran, Swetha Raman, Elizabeth Vinod, Rajalakshmi Rajasegaran, Kamalakannan Vadivel, Anand Bhaskar, Sathya Subramani
The major membrane currents responsible for sinoatrial and idioventricular rhythm-generation were studied in isolated rat heart preparations, perfused in Langendorff mode. The rates of whole isolated hearts beating with sinoatrial rhythm decreased wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ce2663fb17762b48bd8e3678dbf470f
https://doi.org/10.1101/2023.02.28.529494
https://doi.org/10.1101/2023.02.28.529494
Autor:
Farhan Adam Mukadam, Neetu Prince, Renu Raj, M. Venkateswarulu, Subrata Ghosh, Uwe Beifuss, Swetha Raman, Rajalakshmi Rajasegaran, Abirami Vaithiyalingam, Benjamin Jebaraj, Anand Bhaskar, Soosai Manickam Amirtham, Elanchezhian Rajendran, Jürgen Conrad, Sathya Subramani, Iswar Chandra Mondal
Publikováno v:
ACS Omega, Vol 6, Iss 38, Pp 24553-24561 (2021)
ACS Omega
ACS Omega
Cleistanthus collinus leaf extracts are consumed for suicidal purposes in southern India. The boiled decoction is known to be more toxic than the fresh leaf juice. Although several compounds have been isolated and their toxicity tested, controversy r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00bdc96a98b9eca37178b301034d97a9
https://doaj.org/article/ce4b72e3a0ee4415b3a165d7af01459a
https://doaj.org/article/ce4b72e3a0ee4415b3a165d7af01459a
Autor:
Robin M. Hallett, Ester Bonfill-Teixidor, Raffaella Iurlaro, Alexandra Arias, Swetha Raman, Peter Bayliss, Olga Egorova, Almudena Neva-Alejo, AJ Robert McGray, Esther Lau, Alexandre Bosch, Melissa Beilschmidt, Dorothea Maetzel, Johan Fransson, Isabel Huber-Ruano, Judit Anido, Jean-Philippe Julien, Patricia Giblin, Joan Seoane
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research.
Purpose:Leukemia inhibitory factor (LIF) is a multifunctional cytokine with numerous reported roles in cancer and is thought to drive tumor development and progression. Characterization of LIF and clinical-stage LIF inhibitors would increase our unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52114ccf48df1069fba559699b7a33bc
https://pubmed.ncbi.nlm.nih.gov/36441800
https://pubmed.ncbi.nlm.nih.gov/36441800
Autor:
Jeanne Magram, Ying Fu, Stephane Angers, Kevin K. Lin, Melissa Beilschmidt, Jean-Philippe Julien, Alejandro Duque, Jason Moffat, Keith Mascall, Francine Lui, Sachdev S. Sidhu, Swetha Raman, Minh D. To, Mark Ng, Yazen Jmeian, Minerva Fernandez, Xiaowei Wang, Guohua Pan, Angus M. Sinclair, Johan E. S. Fransson
Publikováno v:
Proceedings of the National Academy of Sciences. 116:6812-6817
Aberrant activation of Wnt/β-catenin signaling occurs frequently in cancer. However, therapeutic targeting of this pathway is complicated by the role of Wnt in stem cell maintenance and tissue homeostasis. Here, we evaluated antibodies blocking 6 of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2465a558324ba0db09a6e63c504a3055
https://doi.org/10.1073/pnas.1817246116
https://doi.org/10.1073/pnas.1817246116
Autor:
Yimei Li, John M. Maris, Swetha Raman, Jean-Philippe Julien, Bruce R. Pawel, Maria Lane, Dimiter S. Dimitrov, Kristen A. Upton, Kristopher R. Bosse, Daniel B. Harmon, Carmen T. Navia, Doncho V. Zhelev, Hong Cui, Khushbu Patel, Samantha Buongervino, Yanping Wang, Komal S. Rathi, Zhongyu Zhu, Daniel Martinez, Benjamin Martinez
Publikováno v:
Cell Reports Medicine
Summary Glypican 2 (GPC2) is a MYCN-regulated, differentially expressed cell-surface oncoprotein and target for immune-based therapies in neuroblastoma. Here, we build on GPC2’s immunotherapeutic attributes by finding that it is also a highly expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79f0da2036e550e813c69ffa152235c5
https://pubmed.ncbi.nlm.nih.gov/34337560
https://pubmed.ncbi.nlm.nih.gov/34337560