Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Swetarka Das"'
Autor:
Tanu Garg, Swetarka Das, Shriya Singh, Mohmmad Imran, Atri Mukhopadhyay, Umesh D. Gupta, Sidharth Chopra, Arunava Dasgupta
Publikováno v:
Frontiers in Microbiology, Vol 13 (2023)
IntroductionMycobacterium tuberculosis (Mtb), one of the deadliest human pathogen, has evolved with different strategies of survival inside the host, leading to a chronic state of infection. Phagosomally residing Mtb encounters a variety of stresses,
Externí odkaz:
https://doaj.org/article/17bf59cc43fc48a9bacd86d3854197dc
Publikováno v:
Plants, Vol 12, Iss 7, p 1495 (2023)
Causonis trifolia (L.) Mabb. & J.Wen, commonly known as “fox grape”, is an ethnomedicinally important twining herb of the Vitaceae family, and it is used by ethnic communities for its wide range of therapeutic properties. Our research aims to inv
Externí odkaz:
https://doaj.org/article/2e91a75de8644849b6e12ced375e1ffe
Autor:
Mousumi Shyam, Harshita Verma, Gourab Bhattacharje, Piyali Mukherjee, Samsher Singh, Sujit Kamilya, Pushpendu Jalani, Swetarka Das, Arunava Dasgupta, Abhishake Mondal, Amit Kumar Das, Amit Singh, Federico Brucoli, Claire Bagnéris, Rachael Dickman, Vinay N. Basavanakatti, Patibandla Naresh Babu, Vadivelan Sankaran, Abhimanyu Dev, Barij Nayan Sinha, Sanjib Bhakta, Venkatesan Jayaprakash
Publikováno v:
Journal of medicinal chemistry. 65(1)
In this study, we have designed and synthesized pyrazoline analogues that partially mimic the structure of mycobactin, to address the requirement of novel therapeutics to tackle the emerging global challenge of antimicrobial resistance (AMR). Our inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e51c99d962f8184f900a8992daa94e6
https://pubmed.ncbi.nlm.nih.gov/34981940
https://pubmed.ncbi.nlm.nih.gov/34981940
Autor:
Andrii Karpus, Régis Laurent, Shriya Singh, Vishwa Deepak Tripathi, Jean-Pierre Majoral, Kishore K. Srivastava, Dheerj Soam, Anke Steinmetz, Ramakrishna Gandikota, Serge Mignani, Anne-Marie Caminade, Rama P. Tripathi, Swetarka Das, Arunava Dasgupta
Publikováno v:
Biomacromolecules
Biomacromolecules, American Chemical Society, 2021, 22 (6), pp.2659-2675. ⟨10.1021/acs.biomac.1c00355⟩
Biomacromolecules, 2021, 22 (6), pp.2659-2675. ⟨10.1021/acs.biomac.1c00355⟩
Biomacromolecules, American Chemical Society, 2021, 22 (6), pp.2659-2675. ⟨10.1021/acs.biomac.1c00355⟩
Biomacromolecules, 2021, 22 (6), pp.2659-2675. ⟨10.1021/acs.biomac.1c00355⟩
International audience; The long-term treatment of tuberculosis (TB) sometimes leads to nonadherence to treatment, resulting in multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis. Inadequate bioavailability of the drug is the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0a7a49828ca29804dd673b2019cd3e9
https://hal.archives-ouvertes.fr/hal-03273968
https://hal.archives-ouvertes.fr/hal-03273968
Publikováno v:
Current Topics in Medicinal Chemistry. 19:579-593
DNA gyrase is a clinically validated drug target, currently targeted only by fluoroquinolone class of antibacterials. However, owing to increasing drug resistance as well as a concomitant reduction in the availability of newer classes of antibiotics,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::678aa1295fd3d346a85e7baaa7915bb5
https://doi.org/10.2174/1568026619666190304130218
https://doi.org/10.2174/1568026619666190304130218
Autor:
A. Ansari, S.D. Pandey, Ashish Arora, K.S. Shrimant, Sarita Tripathi, Sidharth Chopra, Swetarka Das, Arunava Dasgupta, J. Venkatesh Pratap
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1867:317-330
The availability of complete genome sequence of Mycobacterium tuberculosis has provided an important tool to understand the mycobacterial biology with respect to host-pathogen interaction, which is an unmet need of the hour owing to continuous increa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a14ec5801f676989f1a2470587936368
https://doi.org/10.1016/j.bbapap.2018.10.011
https://doi.org/10.1016/j.bbapap.2018.10.011
Autor:
Budai Shanmukha Vivek Vinod, Umeshkumar Vekariya, Swetarka Das, Raj Kamal Tripathi, Tanu Garg, Arunava Dasgupta, Kavita Rawat
Publikováno v:
Life Sciences. 220:21-31
Aims β casein fragment peptide (54–59) downregulates Basic Transcription factor 3a (BTF3a) in macrophages and exhibits enhanced clearance of M. bovis BCG and several other intracellular pathogens. However, the direct effect of BTF3a downregulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e927f03d5b6d0d5a93c8939b50a120c0
https://doi.org/10.1016/j.lfs.2019.01.035
https://doi.org/10.1016/j.lfs.2019.01.035
Autor:
A. K. Singh, Anil Patidar, Ritesh P. Thakare, Manoj Raje, Ajay Kumar, Vishant Mahendra Boradia, Chaaya Iyengar Raje, Swetarka Das, Zahid Gani, Sidharth Chopra, Arunava Dasgupta
Publikováno v:
Journal of Antimicrobial Chemotherapy. 74:912-920
Background The emergence of drug-resistant bacteria is a major hurdle for effective treatment of infections caused by Mycobacterium tuberculosis and ESKAPE pathogens. In comparison with conventional drug discovery, drug repurposing offers an effectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5da865ec99f16d0c7e845f4bed1f855c
https://doi.org/10.1093/jac/dky555
https://doi.org/10.1093/jac/dky555
Autor:
Serge, Mignani, Vishwa Deepak, Tripathi, Dheerj, Soam, Rama Pati, Tripathi, Swetarka, Das, Shriya, Singh, Ramakrishna, Gandikota, Regis, Laurent, Andrii, Karpus, Anne-Marie, Caminade, Anke, Steinmetz, Arunava, Dasgupta, Kishore Kumar, Srivastava, Jean-Pierre, Majoral
Publikováno v:
Biomacromolecules. 22(6)
The long-term treatment of tuberculosis (TB) sometimes leads to nonadherence to treatment, resulting in multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis. Inadequate bioavailability of the drug is the main factor for therape
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1ecc9a2cd545543f8e8d0efdb96819a4
https://pubmed.ncbi.nlm.nih.gov/33970615
https://pubmed.ncbi.nlm.nih.gov/33970615
Autor:
Ritesh P. Thakare, Amit K. Pandey, Swetarka Das, Alok Kumar Singh, Manitosh Pandey, Arunava Dasgupta, Pratiksha Karaulia, Sidharth Chopra, Isha Soni
Publikováno v:
Journal of Antimicrobial Chemotherapy. 72:3117-3121
Background Novel drug discovery against non-tuberculous mycobacteria is beset with a large number of challenges including the existence of myriad innate drug resistance mechanisms as well as a lack of suitable animal models, which hinders effective t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4dbe4bef02c4ad859c6d0cd905f1db4
https://doi.org/10.1093/jac/dkx277
https://doi.org/10.1093/jac/dkx277