Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Sweta Vangaveti"'
Autor:
Bharath Raj Madhanagopal, Hannah Talbot, Arlin Rodriguez, Jiss Maria Louis, Hana Zeghal, Sweta Vangaveti, Kaalak Reddy, Arun Richard Chandrasekaran
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Synthetic DNA motifs form the basis of nucleic acid nanotechnology. The biochemical and biophysical properties of these motifs determine their applications. Here, we present a detailed characterization of switchback DNA, a globally left-hand
Externí odkaz:
https://doaj.org/article/af5daedab0f147729fbded92d056feb4
Autor:
Ya Ying Zheng, Ricky Dartawan, Yuhan Wu, Chengze Wu, Hope Zhang, Jeanne Lu, Ashley Hu, Sweta Vangaveti, Jia Sheng
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
The telomeric DNA, a distal region of eukaryotic chromosome containing guanine-rich repetitive sequence of (TTAGGG)n, has been shown to adopt higher-order structures, specifically G-quadruplexes (G4s). Previous studies have demonstrated the implicati
Externí odkaz:
https://doaj.org/article/e3862420c07f45f2953bf77039e883b1
High-throughput single-molecule quantification of individual base stacking energies in nucleic acids
Autor:
Jibin Abraham Punnoose, Kevin J. Thomas, Arun Richard Chandrasekaran, Javier Vilcapoma, Andrew Hayden, Kacey Kilpatrick, Sweta Vangaveti, Alan Chen, Thomas Banco, Ken Halvorsen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
In this work, the authors use a centrifuge force microscope for high-throughput single-molecule experiments to elucidate stacking energies between individual bases of DNA.
Externí odkaz:
https://doaj.org/article/ef0ecd059a474bb888ca39c3aacfb9e0
Autor:
Brittany A. Elliott, Hsiang-Ting Ho, Srivathsan V. Ranganathan, Sweta Vangaveti, Olga Ilkayeva, Hala Abou Assi, Alex K. Choi, Paul F. Agris, Christopher L. Holley
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
The post-transcriptional modification of mRNAs provides an additional layer to gene expression regulation. Here the authors show that 2′-O-methylation mediated by box C/D snoRNAs and fibrillarin can inhibit the translation of target mRNAs.
Externí odkaz:
https://doaj.org/article/b5583f16311b4eff9351aede56bc09e1
Autor:
Amithi Narendran, Sweta Vangaveti, Srivathsan V. Ranganathan, Emily Eruysal, Miranda Craft, Omar Alrifai, Fu Yee Chua, Kathryn Sarachan, Breann Litwa, Sheetal Ramachandran, Paul F. Agris
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2021)
Human Genome Wide Association Studies found a significant risk of Type 2 Diabetes Mellitus (T2DM) in single nucleotide polymorphisms in the cdkal1 gene. The cdkal1 gene is remote from the insulin gene and with the surprising function of a specific tR
Externí odkaz:
https://doaj.org/article/7e2efb8a6d744d18a4c00bda6520c179
Autor:
Phensinee Haruehanroengra, Sweta Vangaveti, Srivathsan V. Ranganathan, Song Mao, Max Daniel Su, Alan A. Chen, Jia Sheng
Publikováno v:
iScience, Vol 23, Iss 12, Pp 101866- (2020)
Summary: Geranylation is a hydrophobic modification discovered in several bacteria tRNAs with the function of promoting codon bias during translation. However, why nature selects this C10-geranyl group remains a question. We conduct synthesis, UV-the
Externí odkaz:
https://doaj.org/article/b0aeac3d78f54c5792f4e7f6a8624aff
Autor:
Daniel Woods, Sweta Vangaveti, Ikechukwu Egbanum, Allison M. Sweeney, Zhong Li, Valjean Bacot-Davis, Danielle S. LeSassier, Matthew Stanger, Gabrielle E. Hardison, Hongmin Li, Marlene Belfort, Christopher W. Lennon
Publikováno v:
mBio, Vol 11, Iss 4 (2020)
ABSTRACT Inteins, as posttranslational regulatory elements, can tune protein function to environmental changes by conditional protein splicing (CPS). Translated as subdomains interrupting host proteins, inteins splice to scarlessly join flanking sequ
Externí odkaz:
https://doaj.org/article/b2f33535d95e4d2088e994a5737fc469
Autor:
Vibhav Valsangkar, Sweta Vangaveti, Goh Woon Lee, Walid M. Fahssi, Waqas S. Awan, Yicheng Huang, Alan A. Chen, Jia Sheng
Publikováno v:
Molecules, Vol 26, Iss 15, p 4620 (2021)
The thrombin binding aptamer (TBA) is a promising nucleic acid-based anticoagulant. We studied the effects of chemical modifications, such as dendrimer Trebler and NHS carboxy group, on TBA with respect to its structures and thrombin binding affinity
Externí odkaz:
https://doaj.org/article/2f51dd94c8d045b286a8674547bb510e
Autor:
Hiba Faheem, Johnsi Mathivanan, Hannah Talbot, Hana Zeghal, Sweta Vangaveti, Jia Sheng, Alan A Chen, Arun Richard Chandrasekaran
Publikováno v:
Nucleic Acids Research. 51:4055-4063
The ability to create stimuli-responsive DNA nanostructures has played a prominent role in dynamic DNA nanotechnology. Primary among these is the process of toehold-based strand displacement, where a nucleic acid molecule can act as a trigger to caus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9559a8296f182ec7651e2c68bbf8206
https://doi.org/10.1093/nar/gkac1152
https://doi.org/10.1093/nar/gkac1152
Autor:
Subodh K. Mishra, Sawyer M. Hicks, Jesus A. Frias, Sweta Vangaveti, Masayuki Nakamori, John D. Cleary, Kaalak Reddy, J. Andrew Berglund
Myotonic dystrophy is a multisystemic neuromuscular disease caused by either a CTG repeat expansion inDMPK(DM1) or a CCTG repeat expansion inCNBP(DM2). Transcription of the expanded alleles produces toxic gain-of-function RNA that sequester the MBNL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a3c829ed7e0874e8d64b3c410b07c0b
https://doi.org/10.1101/2023.02.02.526846
https://doi.org/10.1101/2023.02.02.526846
