Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sweta Parikh"'
Publikováno v:
Journal of pharmaceutical sciences. 109(6)
Drug-induced liver injury (DILI) remains a challenge and a leading risk for drug discovery. Three-dimensional liver spheroids made from primary human hepatocytes (PHHs) with, or without, other liver cell types can provide more physiological relevance
Publikováno v:
Drug Metabolism and Pharmacokinetics. 34:S72
Autor:
Yulong Hong, Daochuan Li, Ronald A Faris, Hongbing Wang, Rongjun Zuo, Sweta Parikh, Feng Li, Kirsten L Cooper, Jin Liu, Li Cao
Publikováno v:
Drug Metabolism and Disposition
Metabolism enzyme induction-mediated drug-drug interactions need to be carefully characterized in vitro for drug candidates to predict in vivo safety risk and therapeutic efficiency. Currently, both the Food and Drug Administration and European Medic
Autor:
Sweta Parikh, Bal Ram Singh
Publikováno v:
The Protein Journal. 26:19-28
In an effort to compare the molecular basis of differential toxic activity of botulinum neurotoxin A (BoNT/A) and BoNT/E, we have analyzed their membrane channel activity by measuring calcein release from liposomes. Both BoNT/A and /E showed a same l
Autor:
Rongjun Zuo, Sweta Parikh, Christopher J. Patten, Charles L. Crespi, Ronald A. Faris, Kirsten Cooper, Feng Li, Jin Liu, Na Li, Mercyanne Andes
Publikováno v:
The FASEB Journal. 29
Increasing evidence shows that drug transporters play an important role in drug-induced hepatotoxicity and adverse drug-drug interactions. Regulatory agencies (USFDA and EMA) recommend in their dru...
Autor:
Christopher J. Patten, Charles L. Crespi, Sweta Parikh, Ronald A. Faris, Jin Liu, Feng Li, Rongjun Zuo, Kirsten Cooper
Publikováno v:
Drug Metabolism and Pharmacokinetics. 32:S106