Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Sweta B. Patel"'
Autor:
Jin-Yong Chung, Yongjie Ma, Dingguo Zhang, Hayden H. Bickerton, Eric Stokes, Sweta B. Patel, Hubert M. Tse, Joseph Feduska, Rob S. Welner, Ronadip R. Banerjee
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106439- (2023)
Summary: Pancreatic β-cell mass expands during pregnancy and regresses in the postpartum period in conjunction with dynamic metabolic demands on maternal glucose homeostasis. To understand transcriptional changes driving these adaptations in β-cell
Externí odkaz:
https://doaj.org/article/e462455c24ea41eba113a99958e8fbf9
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Therapeutic targeting of leukemic stem cells is widely studied to control leukemia. An emerging approach gaining popularity is altering metabolism as a potential therapeutic opportunity. Studies have been carried out on hematopoietic and leukemic ste
Externí odkaz:
https://doaj.org/article/f9979ec3a0f74681b5d9828075a35beb
Autor:
Virginia Camacho, Victoria R. Matkins, Sweta B. Patel, Jeremie M. Lever, Zhengqin Yang, Li Ying, Ashley E. Landuyt, Emma C. Dean, James F. George, Henry Yang, Paul Brent Ferrell, Craig L. Maynard, Casey T. Weaver, Heth R. Turnquist, Robert S. Welner
Publikováno v:
JCI Insight, Vol 5, Iss 22 (2020)
The nonimmune roles of Tregs have been described in various tissues, including the BM. In this study, we comprehensively phenotyped marrow Tregs, elucidating their key features and tissue-specific functions. We show that marrow Tregs are migratory an
Externí odkaz:
https://doaj.org/article/1f60283a5d9849e4826f16038c6c5f98
Isolation of DNA-free RNA from human bone marrow mononuclear cells: comparison of laboratory methods
Publikováno v:
BioTechniques, Vol 68, Iss 3, Pp 159-162 (2020)
RNA quality (purity and integrity) and quantity are of critical importance to ensure reliable gene expression analysis, reproducibility of RNA sequencing and microarray data and validation by RT-PCR. Currently available methods for isolating RNA eith
Externí odkaz:
https://doaj.org/article/b5f06b31ba274a758e64d63733fa8b1b
Autor:
Carissa D Powers, Maya R Sternberg, Sweta B Patel, Christine M Pfeiffer, Renee J Storandt, Rosemary L Schleicher
Publikováno v:
The Journal of Applied Laboratory Medicine. 8:272-284
Background We compared serum vitamin C (VIC) status of the adult (≥20 y) US population in the National Health and Nutrition Examination Survey (NHANES) 2017–2018 with combined data from 2003–2004 and 2005–2006. Methods VIC was measured using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70343b04c6b37763c06d5764de753ad2
https://doi.org/10.1093/jalm/jfac093
https://doi.org/10.1093/jalm/jfac093
Autor:
Shanshan Pei, Austin E Gillen, Ian T Shelton, Brett M Stevens, Maura Gasparetto, Krysta Engel, Sarah Staggs, Yanan Wang, William Showers, Anagha Inguva, Maria L Amaya, Mohammad Minhajuddin, Amanda Winters, Sweta B Patel, Hunter Tolison, Anna Krug, Tracy N Young, Jeffrey Schowinsky, Christine McMahon, Clayton A Smith, Daniel A Pollyea, Craig T Jordan
The BCL-2 inhibitor venetoclax has recently emerged as an important component of acute myeloid leukemia (AML) therapy. Notably, use of this agent has revealed a previously unrecognized form of pathogenesis characterized by monocytic disease progressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9efe46ddecc25398968ad80a8b273adc
https://doi.org/10.1101/2022.12.04.519036
https://doi.org/10.1101/2022.12.04.519036
Autor:
Sweta B. Patel, Jake Y. Chen, Zongliang Yue, Victor M. Darley-Usmar, Brittany L. Crown, Ravi Bhatia, Daniel G. Tenen, Rui Lu, Li Ying, Paul Brent Ferrell, Davide Stefanoni, Ashley T. Hoang, Samuel L. Wolock, Danielle Tenen, Travis Nemkov, Angelo D'Alessandro, Robert S. Welner, Jihye Park, Henry Yang, Valeriya Kuznetsova, Gloria A. Benavides, Mahmoud A. Bassal, Virginia Camacho, Victoria R. Matkins
Publikováno v:
Leukemia
Leukemic stem cells (LSCs) can acquire non-mutational resistance following drug treatment leading to therapeutic failure and relapse. However, oncogene-independent mechanisms of drug persistence in LSCs are incompletely understood, which is the prima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f73c6ca4abbc6e8ae6be675a382c70d
https://doi.org/10.1038/s41375-021-01315-0
https://doi.org/10.1038/s41375-021-01315-0
Autor:
Sweta B. Patel, Valeriya Kuznetsova, Victoria R. Matkins, Alana M. Franceski, Mahmoud A. Bassal, Robert S. Welner
Publikováno v:
Experimental hematology. 115
Despite decades of research, standard therapies remain ineffective for most leukemias, pushing toward an essential unmet need for targeted drug screens. Moreover, preclinical drug testing is an important consideration for success of clinical trials w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdcee51444e8bf76420a7e589bdfeeb0
https://pubmed.ncbi.nlm.nih.gov/36115580
https://pubmed.ncbi.nlm.nih.gov/36115580
Autor:
Sweta B. Patel, Kathryn I. Sunthankar, P. Brent Ferrell, Matthew T. Jenkins, Robert S. Welner, Candace H. Cote
Publikováno v:
Leukemia
Mutations in isocitrate dehydrogenase 2 (IDH2) have been noted to impact cellular differentiation in addition to DNA and histone methylation. However, little is known about the impact of IDH2 mutations on intracellular signaling. Using an isogenic ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82543fd8606e71332722fba4c13d0911
https://europepmc.org/articles/PMC9066619/
https://europepmc.org/articles/PMC9066619/
Autor:
Hajime Karasuyama, Nouraiz Ahmed, Kensuke Miyake, Francisco Marchi, Shin-Young Park, Haoran Zhang, Anuya Paranjape, Marta Borchiellini, Stephen J. Galli, Sisi Chen, Junyan Zhang, Daniel G. Tenen, Elaine Dzierzak, Annalisa Di Ruscio, Sweta B. Patel, Samanta A. Mariani, Timm Schroeder, Mindy Tsai, Mahmoud A. Bassal, Robert S. Welner, Anais Wanet
Publikováno v:
Science Immunology, 6 (56)
E-cadherin is a calcium-dependent cell-cell adhesion molecule extensively studied for its involvement in tissue formation, epithelial cell behavior, and suppression of cancer. However, E-cadherin expression in the hematopoietic system has not been fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e14cf63142a138cb375cba377e4918f5
https://doi.org/10.1126/sciimmunol.aba0178
https://doi.org/10.1126/sciimmunol.aba0178