Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Swen, Hülsmann"'
Autor:
Amara Khan, M. Andrea Markus, Angelika Svetlove, Swen Hülsmann, Frauke Alves, Christian Dullin
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Lung fibrosis (LF) is a chronic progressive, incurable, and debilitating condition of the lung, which is associated with different lung disease. Treatment options are still sparse. Nintedanib, an oral tyrosine kinase inhibitor, significantly
Externí odkaz:
https://doaj.org/article/b1ac6d3eb76a48448df9952bc00cd827
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 6, p 3128 (2024)
The preBötzinger complex (preBötC) and the Bötzinger complex (BötC) are interconnected neural circuits that are involved in the regulation of breathing in mammals. Fast inhibitory neurotransmission is known to play an important role in the intera
Externí odkaz:
https://doaj.org/article/f10f982c4eca4ef9944f8067cd467740
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract To examine whether and how the inspiratory neuronal network in the preBötzinger complex (preBötC) develops during the early postnatal period, we quantified the composition of the population of inspiratory neurons between postnatal day 1 (p
Externí odkaz:
https://doaj.org/article/c9acb6c368664814b5e87e503789224e
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
The neuronal activity in the respiratory network strongly depends on a variety of different neuromodulators. Given the essential role of astrocytes in stabilizing respiratory network activity generated by neurons in the preBötzinger complex (preBöt
Externí odkaz:
https://doaj.org/article/5fda453e430842d1ac8a00a95bda4fba
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Angiotensin II (Ang II) is the primary modulator of the renin-angiotensin system and has been widely studied for its effect on the cardiovascular system. While a few studies have also indicated an involvement of Ang II in the regulation of breathing,
Externí odkaz:
https://doaj.org/article/18bac9eb301c41a7839fc2f5fc9d2722
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Whole-body plethysmography (WBP) is an established method to determine physiological parameters and pathophysiological alteration of breathing in animals and animal models of a variety of diseases. Although frequently used, there is ongoing
Externí odkaz:
https://doaj.org/article/8c0777891b084aa79e14710b32cb0085
Autor:
Amara Khan, Andrea Markus, Thomas Rittmann, Jonas Albers, Frauke Alves, Swen Hülsmann, Christian Dullin
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract X-ray based lung function (XLF) as a planar method uses dramatically less X-ray dose than computed tomography (CT) but so far lacked the ability to relate its parameters to pulmonary air volume. The purpose of this study was to calibrate the
Externí odkaz:
https://doaj.org/article/ceea1a46388e43879f7803acbb7f1a29
CMTM6 expressed on the adaxonal Schwann cell surface restricts axonal diameters in peripheral nerves
Autor:
Maria A. Eichel, Vasiliki-Ilya Gargareta, Elisa D’Este, Robert Fledrich, Theresa Kungl, Tobias J. Buscham, Katja A. Lüders, Cristina Miracle, Ramona B. Jung, Ute Distler, Kathrin Kusch, Wiebke Möbius, Swen Hülsmann, Stefan Tenzer, Klaus-Armin Nave, Hauke B. Werner
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Myelinating cells differentially myelinate axons of different diameters, however whether they can also restrict radial axonal growth remained unclear. Here, the authors show that CMTM6 in Schwann cells restricts axon diameters, affecting sensory nerv
Externí odkaz:
https://doaj.org/article/cd5b24a40b18428fa39de773cdde5765
Publikováno v:
Frontiers in Physiology, Vol 11 (2021)
Acute respiratory distress syndrome (ARDS) represents an acute diffuse inflammation of the lungs triggered by different causes, uniformly leading to a noncardiogenic pulmonary edema with inhomogeneous densities in lung X-ray and lung CT scan and acut
Externí odkaz:
https://doaj.org/article/32cdea16b982476781b2bbc0e4c747b6
Autor:
Angelika Svetlove, Jonas Albers, Swen Hülsmann, Marietta Andrea Markus, Jana Zschüntzsch, Frauke Alves, Christian Dullin
Publikováno v:
Cells, Vol 11, Iss 5, p 918 (2022)
Duchenne muscular dystrophy (DMD) is the most common x-chromosomal inherited dystrophinopathy which leads to progressive muscle weakness and a premature death due to cardiorespiratory dysfunction. The mdx mouse lacks functional dystrophin protein and
Externí odkaz:
https://doaj.org/article/ff8baac36bd24b759b3ca536fdcdf6eb