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of 3
pro vyhledávání: '"Sweena Parmar"'
Autor:
Shannon Moore-Langston, Yuchuan Ding, Jung Min Kim, Sweena Parmar, Vance L Fredrickson, Radhika Rastogi, Omar Elmadoun
Publikováno v:
Current Medicinal Chemistry. 22:1194-1204
Currently, stroke researchers are racing to develop neuroprotective strategies that shield the brain from ischemia-induced injury. To date, neuroprotective agents that have shown promise in animal studies have failed in clinical trials. Since the pat
Autor:
Sweena Parmar, William A Li, Xiaokun Geng, Changya Peng, Xuemei Li, Huishan Du, Feng Ling, Tia Chakraborty, Yuchuan Ding, José A. Rafols, Xiaomu Tan, Xunming Ji, Murali Guthikonda
Publikováno v:
Brain Research. 1531:17-24
The effect of normobaric oxygen (NBO) on apoptosis remains controversial. The present study evaluated the effect of NBO on ischemia-induced apoptosis and assessed the potential for improved outcomes by combining NBO administration with another neurop
Publikováno v:
Stroke. 44
Objectives: Normobaric oxygenation (NBO) has been shown to provide neuroprotection in vivo and in vitro . Yet, a recent Phase 2 clinical trial investigating NBO therapy in acute ischemic stroke was terminated due to questionable therapeutic benefit.