Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Sweena M. Chaudhari"'
Autor:
Clément Cochain, Sweena M Chaudhari, Miriam Koch, Heinz Wiendl, Hans-Henning Eckstein, Alma Zernecke
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93280 (2014)
T cell activation represents a double-edged sword in atherogenesis, as it promotes both pro-inflammatory T cell activation and atheroprotective Foxp3(+) regulatory T cell (Treg) responses. Here, we investigated the role of the co-inhibitory receptor
Externí odkaz:
https://doaj.org/article/1cea0d79e1f14d378b0627f7523af691
Autor:
Prasad Kokate, Deepak Y. Patil, Sneha Srivastava, Santosh Jadhav, Sweena M. Chaudhari, Pragya D Yadav, Vijay P. Bondre, Anita M. Shete, Devendra T. Mourya
Publikováno v:
Infection, Genetics and Evolution. 44:122-126
During a study on Japanese encephalitis (JE) from Kolar district of Karnataka state, India in 1986; two virus isolates were obtained in infant Swiss albino mouse from a pig and a human serum sample. For characterization of these virus isolates, they
Autor:
Helga D. Manthey, Kristina Lorenz, Marc W. Nolte, Alma Zernecke, Martin Busch, Sweena M. Chaudhari, Miriam Koch, Bernhard Nieswandt, Manuel Yepes, David Stegner, Clément Cochain, Sandra Vorlova
SummaryAtherosclerosis is considered a chronic inflammatory disease of the vessel wall. Coagulation pathways and immune responses contribute to disease development. The role of coagulation factor XII (FXII) in vascular inflammation, however, remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89b037be060996679f7d07853d21f4ee
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85007291355
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85007291355
Autor:
Helga D. Manthey, Martin Busch, Christian Weber, Alma Zernecke, Jaroslav Pelisek, Ela Karshovska, Miriam Koch, Stefanie Barnsteiner, Rory R. Koenen, Hans-Henning Eckstein, Clément Cochain, Sweena M. Chaudhari
Publikováno v:
Thrombosis and Haemostasis, 110(6), 1267-77. Georg Thieme Verlag
SummaryThe chemokine receptor CCR6 is expressed by various cell subsets implicated in atherogenesis, such as monocytes, Th17 and regulatory T cells. In order to further define the role of CCR6 in atherosclerosis, CCR6-deficient (Ccr6 -/-) mice were c
Autor:
Mihail Hristov, Martin Zenke, Oliver Soehnlein, Yvonne Döring, Sweena M. Chaudhari, Maik Drechsler, Rory R. Koenen, Christian Weber, Helene Hartwig, Thomas Hieronymus, Alma Zernecke, Svenja Meiler, Erdenechimeg Shagdarsuren
Publikováno v:
Arteriosclerosis Thrombosis and Vascular Biology, 32(7), 1613-1623. LIPPINCOTT WILLIAMS & WILKINS
Objective— Inflammatory leukocyte accumulation drives atherosclerosis. Although monocytes/macrophages and polymorphonuclear neutrophilic leukocytes (PMN) contribute to lesion formation, sequelae of myeloproliferative disease remain to be elucidated
Autor:
Laura A. Solt, Ran Wang, Mohammed Amir, Sweena M. Chaudhari, Sean Campbell, Molly A. Bassette, Theodore M. Kamenecka
Publikováno v:
The Journal of Immunology. 200:121.3-121.3
Dysregulated TH17 immune responses have been associated with the pathogenesis of several autoimmune diseases. While full development of TH17 cells requires both nuclear receptors RORα and RORγt, most of the work surrounding TH17 cells has focused o
Autor:
Mohammed Amir, Sweena M. Chaudhari, Ran Wang, Sean Campbell, Theodore M. Kamenecka, Laura A. Solt
Publikováno v:
The Journal of Immunology. 200:163.10-163.10
Th17 cells have been associated with the pathogenesis of several autoimmune diseases, including multiple sclerosis. While the nuclear receptor (NR) RORγt is considered the lineage determining transcription factor for Th17 cells, the REV-ERBs (REV-ER
Autor:
Oliver B. Pelletier, Michael D. Cameron, Laura B. Chopp, Douglas J. Kojetin, Sarah A. Mosure, Mohammed Amir, Sweena M. Chaudhari, Christelle Doebelin, Sean Campbell, Ran Wang, Jinsai Shang, Theodore M. Kamenecka, Qun Lu, Yuanjun He, Laura A. Solt
Publikováno v:
Cell reports
Cell Reports, Vol 25, Iss 13, Pp 3733-3749.e8 (2018)
Cell Reports, Vol 25, Iss 13, Pp 3733-3749.e8 (2018)
SUMMARY RORγt is well recognized as the lineage-defining transcription factor for T helper 17 (TH17) cell development. However, the cell-intrinsic mechanisms that negatively regulate TH17 cell development and autoimmunity remain poorly understood. H
Autor:
Clément Cochain, Agnes Görlach, Frederick Vogel, Jaroslav Pelisek, Sweena M. Chaudhari, Martin Busch, Stephan Kissler, Helga D. Manthey, Manfred B. Lutz, Celia Caballero-Franco, Miriam Koch, Alma Zernecke, Thomas L. Theelen, Judith C. Sluimer, Heike M. Hermanns, Mat J.A.P. Daemen
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology, 35(11), 2316-2325. Lippincott Williams and Wilkins
Arteriosclerosis Thrombosis and Vascular Biology, 35(11), 2316-2325. LIPPINCOTT WILLIAMS & WILKINS
Arteriosclerosis Thrombosis and Vascular Biology, 35(11), 2316-2325. LIPPINCOTT WILLIAMS & WILKINS
Objective— Although immune responses drive the pathogenesis of atherosclerosis, mechanisms that control antigen-presenting cell (APC)–mediated immune activation in atherosclerosis remain elusive. We here investigated the function of hypoxia-induc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2309c25ed250e7204e51c14ebe750ef
https://pure.amc.nl/en/publications/deficiency-of-hif1-in-antigenpresenting-cells-aggravates-atherosclerosis-and-type-1-thelper-cell-responses-in-mice(aa1ea112-edd6-4e65-97bb-64e0a754c16f).html
https://pure.amc.nl/en/publications/deficiency-of-hif1-in-antigenpresenting-cells-aggravates-atherosclerosis-and-type-1-thelper-cell-responses-in-mice(aa1ea112-edd6-4e65-97bb-64e0a754c16f).html
Publikováno v:
The Journal of Immunology. 198:127.15-127.15
A significant amount of work has identified key factors that drive Th17 cell development, including the nuclear receptors (NRs) RORα and RORγ. However, cell-intrinsic mechanisms that negatively regulate Th17 cell development and inflammation have r