Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Swee Sharp"'
Autor:
Steven R. Whittaker, Clare Barlow, Mathew P. Martin, Caterina Mancusi, Steve Wagner, Annette Self, Elaine Barrie, Robert Te Poele, Swee Sharp, Nathan Brown, Stuart Wilson, Wayne Jackson, Peter M. Fischer, Paul A. Clarke, Michael I. Walton, Edward McDonald, Julian Blagg, Martin Noble, Michelle D. Garrett, Paul Workman
Publikováno v:
Molecular Oncology, Vol 12, Iss 3, Pp 287-304 (2018)
Deregulation of the cyclin‐dependent kinases (CDKs) has been implicated in the pathogenesis of multiple cancer types. Consequently, CDKs have garnered intense interest as therapeutic targets for the treatment of cancer. We describe herein the molec
Externí odkaz:
https://doaj.org/article/fe1e3db27bb44f2e82c1a7b2ffc32006
Autor:
Paul Workman, Michael Waterfield, Al Burlingame, Michael Walton, Joanne Salmons, Emmanuel deBilly, Marissa Powers, Swee Sharp, Ian Judson, Udai Banerji, Wynne Aherne, Lindsay Stimson, Rainer Cramer, Marketa Zvelebil, Alice Yang, Akunna Akpan, Jens-Oliver Koopman, Rob Stein, Soren Naaby-Hansen, Paul A. Clarke, Alison Maloney
Supplementary Data URL from Gene and Protein Expression Profiling of Human Ovarian Cancer Cells Treated with the Heat Shock Protein 90 Inhibitor 17-Allylamino-17-Demethoxygeldanamycin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb4b4ebae9087b2c2c46e29324919a96
https://doi.org/10.1158/0008-5472.22368576.v1
https://doi.org/10.1158/0008-5472.22368576.v1
Autor:
Paul Workman, Michael Waterfield, Al Burlingame, Michael Walton, Joanne Salmons, Emmanuel deBilly, Marissa Powers, Swee Sharp, Ian Judson, Udai Banerji, Wynne Aherne, Lindsay Stimson, Rainer Cramer, Marketa Zvelebil, Alice Yang, Akunna Akpan, Jens-Oliver Koopman, Rob Stein, Soren Naaby-Hansen, Paul A. Clarke, Alison Maloney
Supplementary Figure 1 from Gene and Protein Expression Profiling of Human Ovarian Cancer Cells Treated with the Heat Shock Protein 90 Inhibitor 17-Allylamino-17-Demethoxygeldanamycin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1456e7090b27bfeb595dd22afa87203f
https://doi.org/10.1158/0008-5472.22368573
https://doi.org/10.1158/0008-5472.22368573
Autor:
Paul Workman, Michael Waterfield, Al Burlingame, Michael Walton, Joanne Salmons, Emmanuel deBilly, Marissa Powers, Swee Sharp, Ian Judson, Udai Banerji, Wynne Aherne, Lindsay Stimson, Rainer Cramer, Marketa Zvelebil, Alice Yang, Akunna Akpan, Jens-Oliver Koopman, Rob Stein, Soren Naaby-Hansen, Paul A. Clarke, Alison Maloney
The promising antitumor activity of 17-allylamino-17-demethoxygeldanamycin (17AAG) results from inhibition of the molecular chaperone heat shock protein 90 (HSP90) and subsequent degradation of multiple oncogenic client proteins. Gene expression micr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11e8d9964da35d5835cf227d7436ec80
https://doi.org/10.1158/0008-5472.c.6496011.v1
https://doi.org/10.1158/0008-5472.c.6496011.v1
Autor:
Paola B. Arimondo, Christian Bailly, Tracy M. Bryan, Silvia Chioato, Scott B. Cohen, Ian Collins, Robert Blake Crochet, Nicola J. Curtin, William A. Denny, Erling Donnelly, Daniele Generali, Nicolas Guilbaud, Ian R. Hardcastle, Adrian L. Harris, Philip A. Harris, John A. Hartley, Rolf W. Hartmann, Qingzhong Hu, Donna M. Huryn, Federico Innocenti, Harren Jhoti, Keith Jones, Yong-Hwan Lee, David Norton, Puja Pathuri, Gordon W. Rewcastle, Minsuh Seo, Swee Sharp, Zahid H. Siddik, Christopher A. Slapak, Ross Soo, Malcolm F.G. Stevens, David Taylor, Dominic Tisi, Christopher G. Tomlinson, Stephany Veuger, Richard A. Walgren, Henriette Willems, Peter Wipf, Paul Workman, Wei-Peng Yong
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b905b2a0c73213819471cd451da75b1d
https://doi.org/10.1016/b978-0-12-396521-9.01002-0
https://doi.org/10.1016/b978-0-12-396521-9.01002-0
Autor:
Swee, Sharp, Paul, Workman
Publikováno v:
Advances in cancer research. 95
The molecular chaperone heat shock protein 90 (HSP90) has emerged as an exciting molecular target for cancer therapy. It operates as part of a multichaperone complex and is essential for the conformation, stability, and function of several key oncoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e1d550b5401e2b2e5ffada7453ecfef8
https://pubmed.ncbi.nlm.nih.gov/16860662
https://pubmed.ncbi.nlm.nih.gov/16860662
Autor:
Anthea Hardcastle, Kathy Boxall, Juliet Richards, Peter Tomlin, Swee Sharp, Paul Clarke, Paul Workman, Wynne Aherne
Publikováno v:
Assay & Drug Development Technologies; Jun2005, Vol. 3 Issue 3, p273-285, 13p