Zobrazeno 1 - 10
of 408
pro vyhledávání: '"Swee Lay, Thein"'
Autor:
Angelo D’Alessandro, Kang Le, Maureen Lundt, Quan Li, Emily B. Dunkelberger, Troy Cellmer, Andrew J. Worth, Spurthi Patil, Chris Huston, Abby Grier, Monika Dzieciatkowska, Daniel Stephenson, William A. Eaton, Swee Lay Thein
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Mitapivat, a pyruvate kinase (PK) activator, shows great potential as a sickle cell disease (SCD)- modifying therapy. Safety and efficacy of mitapivat as a long-term maintenance therapy is currently being evaluated in two open-label studies. Here we
Externí odkaz:
https://doaj.org/article/d5325d01dfa842ca8f03f72430be3114
Autor:
W. Patricia Bandettini, Sujata M. Shanbhag, Christine Mancini, Delaney R. McGuirt, Peter Kellman, Hui Xue, Jennifer L. Henry, Margaret Lowery, Swee Lay Thein, Marcus Y. Chen, Adrienne E. Campbell-Washburn
Publikováno v:
Journal of Cardiovascular Magnetic Resonance, Vol 22, Iss 1, Pp 1-10 (2020)
Abstract Background There is a renewed interest in lower field magnetic resonance imaging (MRI) systems for cardiovascular magnetic resonance (CMR), due to their favorable physical properties, reduced costs, and increased accessibility to patients wi
Externí odkaz:
https://doaj.org/article/b268a25f4827495abc49b1cd702a4048
Autor:
Eric J. Niesor, Elie Nader, Anne Perez, François Lamour, Renée Benghozi, Alan Remaley, Swee Lay Thein, Philippe Connes
Publikováno v:
Membranes, Vol 12, Iss 11, p 1134 (2022)
Cell membrane lipid composition, especially cholesterol, affects many functions of embedded enzymes, transporters and receptors in red blood cells (RBC). High membrane cholesterol content affects the RBCs’ main vital function, O2 and CO2 transport
Externí odkaz:
https://doaj.org/article/7d041b815cb042a9a1a96293b463b8fc
Publikováno v:
HemaSphere, Vol 5, Iss 6, p e584 (2021)
Sickle cell disease (SCD) is an exemplar of bidirectional translational research, starting with a remarkable astute observation of the abnormally shaped red blood cells that motivated decades of bench research that have now translated into new drugs
Externí odkaz:
https://doaj.org/article/d1673e1d773349c4abdb77d482c79cc2
Autor:
C Coralea Stephanou, P Petros Kountouris, C Carsten W Lederer, C Celeste Bento, C Cornelis L Hartveld, J Jan Traeger-Synodinos, J John S Waye, Z Zhiyu Peng, I Irene Fylaktou, H Hashim Halim-Fikri, T Tamara T. Koopmann, L Landry Nfonsam, J Jun Sun, F Franck Nzengu-Lukusa, M Michael Angastiniotis, C Catherine Badens, B Bertha Ibarra Cortes, J Johan T. den Dunnen, J Jacques Elion, S Suthat Fucharoen, K Kyriaki Michailidou, T Thessalia Papasavva, A Antonio Piga, R Raj Ramesar, S Swee Lay Thein, L Léon Tshilolo, Z Zilfalil Bin Alwi, M Marina Kleanthous
Publikováno v:
HemaSphere, Vol 6, Pp 34-35 (2022)
Externí odkaz:
https://doaj.org/article/2ac140c7db5a45d3b792af508f21b296
Publikováno v:
Bio-Protocol, Vol 11, Iss 4 (2021)
The formation of neutrophil extracellular traps (NETs) is thought to play a critical role in infections and propagating sterile inflammation. Histone citrullination is an essential and early step in NETs formation, detectable prior to the formation o
Externí odkaz:
https://doaj.org/article/5a93abc71c584d4aa01fbb3da59c9abe
Autor:
John N. Brewin, Helen Rooks, Kate Gardner, Harry Senior, Mrinmayi Morje, Hamel Patel, David Calvet, Pablo Bartolucci, Swee-Lay Thein, Stephan Menzel, David C. Rees
Publikováno v:
Haematologica, Vol 106, Iss 6 (2020)
Externí odkaz:
https://doaj.org/article/c28b2f15c0fa40b79880153968ee1f14
Autor:
Laurel A. Menapace, Swee Lay Thein
Publikováno v:
Haematologica, Vol 105, Iss 11 (2020)
Externí odkaz:
https://doaj.org/article/5ad53f99c83a4db8b82014adf78c090a
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Neutrophil extracellular traps (NETs) formation has been implicated in an increasing number of infectious and non-infectious pathologies. NETosis is a tightly regulated process; the end-stage and read-out is the formation of DNA strands extruded from
Externí odkaz:
https://doaj.org/article/cacd4d3a7bf44e308b14678300b47f7d
Autor:
Swee Lay Thein, France Pirenne, Ross M. Fasano, Anoosha Habibi, Pablo Bartolucci, Satheesh Chonat, Jeanne E. Hendrickson, Sean R. Stowell
Publikováno v:
Haematologica, Vol 105, Iss 3 (2020)
Externí odkaz:
https://doaj.org/article/bf827e8f864d4aa39bd5847cb822da76