Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Swechha M Pokharel"'
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0257576 (2021)
Exaggerated inflammatory response results in pathogenesis of various inflammatory diseases. Tumor Necrosis Factor-alpha (TNF) is a multi-functional pro-inflammatory cytokine regulating a wide spectrum of physiological, biological, and cellular proces
Externí odkaz:
https://doaj.org/article/665937c4076d4c1cbea27137c547987b
Autor:
Nicholas M Negretti, Yinyin Ye, Lais M Malavasi, Swechha M Pokharel, Steven Huynh, Susan Noh, Cassidy L Klima, Christopher R Gourley, Claude A Ragle, Santanu Bose, Torey Looft, Craig T Parker, Geremy Clair, Joshua N Adkins, Michael E Konkel
Publikováno v:
Gut Microbes, Vol 12, Iss 1 (2020)
The symptoms of infectious diarrheal disease are mediated by a combination of a pathogen’s virulence factors and the host immune system. Campylobacter jejuni is the leading bacterial cause of diarrhea worldwide due to its near-ubiquitous zoonotic a
Externí odkaz:
https://doaj.org/article/514f03e05aba4a3b83309a0d4398f590
Autor:
Jeevan B. Gc, Justin Chen, Swechha M. Pokharel, Indira Mohanty, Charles Mariasoosai, Peter Obi, Paul Panipinto, Smarajit Bandyopadhyay, Santanu Bose, Senthil Natesan
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract A growing body of evidence suggests that oxysterols such as 25-hydroxycholesterol (25HC) are biologically active and involved in many physiological and pathological processes. Our previous study demonstrated that 25HC induces an innate immun
Externí odkaz:
https://doaj.org/article/30b27e54f69140f39a4a1fadff107675
Autor:
Swechha M. Pokharel, Indira Mohanty, Charles Mariasoosai, Tanya A. Miura, Lisette A. Maddison, Senthil Natesan, Santanu Bose
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Respiratory Syncytial Virus (RSV) is a non-segmented negative-sense RNA virus belonging to the paramyxovirus family. RSV infects the respiratory tract to cause pneumonia and bronchiolitis in infants, elderly, and immunocompromised patients. Effective
Externí odkaz:
https://doaj.org/article/01cfc0a057b64bceae85084bb13be137
Autor:
Kim Chiok, Swechha M. Pokharel, Indira Mohanty, Lindsay Grace Miller, Shou-Jiang Gao, Arthur L. Haas, Kim C. Tran, Michael N. Teng, Santanu Bose
Publikováno v:
mBio
Paramyxoviruses such as respiratory syncytial virus (RSV) are the leading cause of pneumonia in infants, the elderly, and immunocompromised individuals. Understanding host-virus interactions is essential for the development of effective interventions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::681175b156b4295ed036c49941906345
http://europepmc.org/articles/PMC8764521
http://europepmc.org/articles/PMC8764521
Autor:
Senthil Natesan, Swechha M. Pokharel, Santanu Bose, Te-Hung Chang, Zachary T. Colburn, Su-Yu Tsai, Jeevan B. Gc, Jonathan C. R. Jones, Jesus A. Segovia, Niraj K. Shil, Smarajit Bandyopadhyay
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Nature Communications
Nature Communications
Integrins are components of cell-matrix adhesions, and function as scaffolds for various signal transduction pathways. So far no lipid ligand for integrin has been reported. Here we show that a lipid, oxysterol 25-hydroxycholesterol (25HC), directly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f63b1ee321b7e28a75d399dbe3ec6561
http://link.springer.com/article/10.1038/s41467-019-09453-x
http://link.springer.com/article/10.1038/s41467-019-09453-x
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::546dcca3b67e2ebdaa7e8bb8167a8a1e
https://doi.org/10.1096/fasebj.2021.35.s1.02684
https://doi.org/10.1096/fasebj.2021.35.s1.02684
Publikováno v:
Current Clinical Microbiology Reports. 4:150-158
Inflammasome plays a pivotal role in innate antiviral immunity. Assembly and formation of inflammasome complex, a caspase-1 activating platform, lead to the production of pro-inflammatory cytokines like interleukin (IL)-1β and induction of cell deat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f40eacd7a2c58bc89b75cead305dc771
https://doi.org/10.1007/s40588-017-0070-x
https://doi.org/10.1007/s40588-017-0070-x
Autor:
Ann M. Rajnicek, Christina E. Arnold, Swechha M. Pokharel, Robert N. Barker, Joseph I. Hoare, Colin D. McCaig, Heather M. Wilson
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports
The factors and signals driving T cell activation and polarisation during immune responses have been studied mainly at the level of cells and chemical mediators. Here we describe a physical driver of these processes in the form of physiological-stren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50c088b159c4212b241589924d46a9c7
https://doi.org/10.1038/s41598-019-53898-5
https://doi.org/10.1038/s41598-019-53898-5
Autor:
Swechha M. Pokharel, Claude A. Ragle, Geremy Clair, Christopher R. Gourley, Yinyin Ye, Nicholas M. Negretti, Joshua N. Adkins, Santanu Bose, Lais M Malavasi, Cassidy L. Klima, Steven Huynh, Michael E. Konkel, Torey Looft, Susan Noh, Craig T. Parker
Publikováno v:
Gut Microbes
article-version (VoR) Version of Record
Gut Microbes, Vol 12, Iss 1 (2020)
article-version (VoR) Version of Record
Gut Microbes, Vol 12, Iss 1 (2020)
The symptoms of infectious diarrheal disease are mediated by a combination of a pathogen’s virulence factors and the host immune system. Campylobacter jejuni is the leading bacterial cause of diarrhea worldwide due to its near-ubiquitous zoonotic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9993368114893df051ae28f4c41fd489
https://doi.org/10.1080/19490976.2020.1814121
https://doi.org/10.1080/19490976.2020.1814121