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Efficacy and Safety of a Modified Vaccinia Ankara-NP+M1 Vaccine Combined with QIV in People Aged 65 and Older: A Randomised Controlled Clinical Trial (INVICTUS).

Autor: Butler C; Nuffield Department of Primary Health Care Sciences, University of Oxford, Oxford OX2 6GG, UK., Ellis C; Vaccitech Ltd., Oxford OX4 4GE, UK., Folegatti PM; Jenner Institute, University of Oxford, Oxford OX3 7DQ, UK., Swayze H; Nuffield Department of Primary Health Care Sciences, University of Oxford, Oxford OX2 6GG, UK., Allen J; Nuffield Department of Primary Health Care Sciences, University of Oxford, Oxford OX2 6GG, UK., Bussey L; Vaccitech Ltd., Oxford OX4 4GE, UK., Bellamy D; Jenner Institute, University of Oxford, Oxford OX3 7DQ, UK., Lawrie A; Jenner Institute, University of Oxford, Oxford OX3 7DQ, UK., Eagling-Vose E; Vaccitech Ltd., Oxford OX4 4GE, UK., Yu LM; Nuffield Department of Primary Health Care Sciences, University of Oxford, Oxford OX2 6GG, UK., Shanyinde M; Nuffield Department of Primary Health Care Sciences, University of Oxford, Oxford OX2 6GG, UK., Mair C; Jenner Institute, University of Oxford, Oxford OX3 7DQ, UK., Flaxman A; Jenner Institute, University of Oxford, Oxford OX3 7DQ, UK., Ewer K; Jenner Institute, University of Oxford, Oxford OX3 7DQ, UK., Gilbert S; Jenner Institute, University of Oxford, Oxford OX3 7DQ, UK., Evans TG; Vaccitech Ltd., Oxford OX4 4GE, UK., On Behalf Of The Invictus Investigators

Publikováno v: Vaccines [Vaccines (Basel)] 2021 Aug 03; Vol. 9 (8). Date of Electronic Publication: 2021 Aug 03.

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Akademický článek

Platform Randomised trial of INterventions against COVID-19 In older peoPLE (PRINCIPLE): protocol for a randomised, controlled, open-label, adaptive platform, trial of community treatment of COVID-19 syndromic illness in people at higher risk.

Autor: Hayward G; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK., Butler CC; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK christopher.butler@phc.ox.ac.uk., Yu LM; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK., Saville BR; Berry Consultants, Austin, Texas, USA.; Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Berry N; Berry Consultants, Austin, Texas, USA., Dorward J; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.; Centre for the Aids Programme of Research in South Africa, Durban, South Africa., Gbinigie O; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK., van Hecke O; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK., Ogburn E; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK., Swayze H; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK., Bongard E; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK., Allen J; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK., Tonner S; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK., Rutter H; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK., Tonkin-Crine S; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK., Borek A; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK., Judge D; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK., Grabey J; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK., de Lusignan S; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.; Department of Clinical and Experimental Medicine, University of Surrey, Guildford, UK., Thomas NPB; Windrush Medical Practice, Witney, UK.; Royal College of General Practitioners, London, UK., Evans PH; St Leonard's Research Practice, Exeter, UK.; University of Exeter Medical School, Exeter, UK., Andersson MI; Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK., Llewelyn M; Department of Microbiology and Infection, University Hospitals Sussex NHS Foundation Trust, Brighton, UK.; Department of Global Health and Infection, Brighton and Sussex Medical School, Brighton, UK., Patel M; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK., Hopkins S; Public Health England, London, UK., Hobbs FDR; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.

Publikováno v: BMJ open [BMJ Open] 2021 Jun 18; Vol. 11 (6), pp. e046799. Date of Electronic Publication: 2021 Jun 18.

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Akademický článek

A phase IIb study to determine the safety and efficacy of candidate INfluenza Vaccine MVA-NP+M1 in combination with licensed Ina CTivated infl Uenza vaccine in adult S aged 65 years and above (INVICTUS): a study protocol.

Autor: Swayze H; Primary Care Health Sciences, University of Oxford, Oxford, UK., Allen J; Primary Care Health Sciences, University of Oxford, Oxford, UK., Folegatti P; The Jenner Institute, University of Oxford, Oxford, OX3 7DQ, UK., Yu LM; Primary Care Health Sciences, University of Oxford, Oxford, UK., Gilbert S; The Jenner Institute, University of Oxford, Oxford, OX3 7DQ, UK., Hill A; The Jenner Institute, University of Oxford, Oxford, OX3 7DQ, UK., Ellis C; Vaccitech Limited, Heatley Road, The Oxford Science Park,, Oxford, OX4 4GE, UK., Butler CC; Primary Care Health Sciences, University of Oxford, Oxford, UK.

Publikováno v: F1000Research [F1000Res] 2019 May 23; Vol. 8, pp. 719. Date of Electronic Publication: 2019 May 23 (Print Publication: 2019).

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