Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Swati, Gite"'
Autor:
Rossana Lazcano, Carmelia M. Barreto, Ruth Salazar, Fernando Carapeto, Raymond S. Traweek, Cheuk H. Leung, Swati Gite, Jay Mehta, Davis R. Ingram, Khalida M. Wani, Kim-Anh T. Vu, Edwin R. Parra, Wei Lu, Jianling Zhou, Russell G. Witt, Brandon Cope, Prapassorn Thirasastr, Heather Y. Lin, Christopher P. Scally, Anthony P. Conley, Ravin Ratan, J. Andrew Livingston, Alexandra M. Zarzour, Joseph Ludwig, Dejka Araujo, Vinod Ravi, Shreyaskumar Patel, Robert Benjamin, Jennifer Wargo, Ignacio I. Wistuba, Neeta Somaiah, Christina L. Roland, Emily Z. Keung, Luisa Solis, Wei-Lien Wang, Alexander J. Lazar, Elise F. Nassif
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
IntroductionUndifferentiated pleomorphic sarcoma (UPS) can be associated with a relatively dense immune infiltration. Immune checkpoint inhibitors (anti-PD1, anti-PDL1, and anti-CTLA4) are effective in 20% of UPS patients. We characterize the immune
Externí odkaz:
https://doaj.org/article/0f3178fc4ae44b07859cc53a24e0f97e
Autor:
Michael J. Overman, Jean-Nicolas Vauthey, Scott Kopetz, Chantale Bernatchez, Alda Tam, Robert Jenq, Chia-Chi Chang, Van Morris, Kanwal Raghav, Christine Parseghian, Ching-Wei Tzeng, Luisa Solis, David Menter, Bryan Kee, Andy Futreal, Yun Shin Chun, Dipen M. Maru, Wai Chin Foo, Xiaofei Song, Rebecca S. Slack Tidwell, Ignacio I. Wistuba, Daniele Lorenzini, Swati Gite, Rossana Lazcano, Young Uk Kim, Edwin Roger Parra, Cara Haymaker, Preeti Kanikarla Marie
DEG and GSEA gene set analysis post vs pre treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5abc62019abc8c349dfdd1692a579df
https://doi.org/10.1158/1078-0432.22479279.v1
https://doi.org/10.1158/1078-0432.22479279.v1
Autor:
Michael J. Overman, Jean-Nicolas Vauthey, Scott Kopetz, Chantale Bernatchez, Alda Tam, Robert Jenq, Chia-Chi Chang, Van Morris, Kanwal Raghav, Christine Parseghian, Ching-Wei Tzeng, Luisa Solis, David Menter, Bryan Kee, Andy Futreal, Yun Shin Chun, Dipen M. Maru, Wai Chin Foo, Xiaofei Song, Rebecca S. Slack Tidwell, Ignacio I. Wistuba, Daniele Lorenzini, Swati Gite, Rossana Lazcano, Young Uk Kim, Edwin Roger Parra, Cara Haymaker, Preeti Kanikarla Marie
Post treatment and pre treatment DEG in RFS long vs short
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::983ee5ab9dc04bd4ba0e6fe6550aa74b
https://doi.org/10.1158/1078-0432.22479276.v1
https://doi.org/10.1158/1078-0432.22479276.v1
Autor:
Michael J. Overman, Jean-Nicolas Vauthey, Scott Kopetz, Chantale Bernatchez, Alda Tam, Robert Jenq, Chia-Chi Chang, Van Morris, Kanwal Raghav, Christine Parseghian, Ching-Wei Tzeng, Luisa Solis, David Menter, Bryan Kee, Andy Futreal, Yun Shin Chun, Dipen M. Maru, Wai Chin Foo, Xiaofei Song, Rebecca S. Slack Tidwell, Ignacio I. Wistuba, Daniele Lorenzini, Swati Gite, Rossana Lazcano, Young Uk Kim, Edwin Roger Parra, Cara Haymaker, Preeti Kanikarla Marie
Purpose:Despite the prognostic importance of immune infiltrate in colorectal cancer, immunotherapy has demonstrated limited clinical activity in refractory metastatic proficient mismatch-repair (pMMR) colorectal cancer. This study explores combining
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82f7ef4d4056ba5b4a11b6ef600e9660
https://doi.org/10.1158/1078-0432.c.6530172
https://doi.org/10.1158/1078-0432.c.6530172
Autor:
Michael J. Overman, Jean-Nicolas Vauthey, Scott Kopetz, Chantale Bernatchez, Alda Tam, Robert Jenq, Chia-Chi Chang, Van Morris, Kanwal Raghav, Christine Parseghian, Ching-Wei Tzeng, Luisa Solis, David Menter, Bryan Kee, Andy Futreal, Yun Shin Chun, Dipen M. Maru, Wai Chin Foo, Xiaofei Song, Rebecca S. Slack Tidwell, Ignacio I. Wistuba, Daniele Lorenzini, Swati Gite, Rossana Lazcano, Young Uk Kim, Edwin Roger Parra, Cara Haymaker, Preeti Kanikarla Marie
Supplementary figures and supplemental methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81d6bbfdafcf69ff6a51921aebdaf87b
https://doi.org/10.1158/1078-0432.22479285
https://doi.org/10.1158/1078-0432.22479285
Autor:
Michael J. Overman, Jean-Nicolas Vauthey, Scott Kopetz, Chantale Bernatchez, Alda Tam, Robert Jenq, Chia-Chi Chang, Van Morris, Kanwal Raghav, Christine Parseghian, Ching-Wei Tzeng, Luisa Solis, David Menter, Bryan Kee, Andy Futreal, Yun Shin Chun, Dipen M. Maru, Wai Chin Foo, Xiaofei Song, Rebecca S. Slack Tidwell, Ignacio I. Wistuba, Daniele Lorenzini, Swati Gite, Rossana Lazcano, Young Uk Kim, Edwin Roger Parra, Cara Haymaker, Preeti Kanikarla Marie
RFS long and short microbiome-taxa abundance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63db92b54b8c36d327747f8e598ce763
https://doi.org/10.1158/1078-0432.22479273.v1
https://doi.org/10.1158/1078-0432.22479273.v1
Autor:
Michael J. Overman, Jean-Nicolas Vauthey, Scott Kopetz, Chantale Bernatchez, Alda Tam, Robert Jenq, Chia-Chi Chang, Van Morris, Kanwal Raghav, Christine Parseghian, Ching-Wei Tzeng, Luisa Solis, David Menter, Bryan Kee, Andy Futreal, Yun Shin Chun, Dipen M. Maru, Wai Chin Foo, Xiaofei Song, Rebecca S. Slack Tidwell, Ignacio I. Wistuba, Daniele Lorenzini, Swati Gite, Rossana Lazcano, Young Uk Kim, Edwin Roger Parra, Cara Haymaker, Preeti Kanikarla Marie
Treatment related adverse events and list of antibodies used.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac6f35f3c050887ff20f8011f0395e8f
https://doi.org/10.1158/1078-0432.22479282.v1
https://doi.org/10.1158/1078-0432.22479282.v1
Autor:
Neeta Somaiah, Anthony P Conley, Edwin Roger Parra, Heather Lin, Behrang Amini, Luisa Solis Soto, Ruth Salazar, Carmelia Barreto, Honglei Chen, Swati Gite, Cara Haymaker, Elise F Nassif, Chantale Bernatchez, Akash Mitra, John Andrew Livingston, Vinod Ravi, Dejka M Araujo, Robert Benjamin, Shreyaskumar Patel, Maria A Zarzour, Sharjeel Sabir, Alexander J Lazar, Wei-Lien Wang, Najat C Daw, Xiao Zhou, Christina L Roland, Zachary A Cooper, Jaime Rodriguez-Canales, Andrew Futreal, Jean-Charles Soria, Ignacio I Wistuba, Patrick Hwu
Publikováno v:
The Lancet. Oncology. 23(9)
Few standard treatment options are available for patients with metastatic sarcomas. We did this trial to evaluate the efficacy, safety, and changes in the tumour microenvironment for durvalumab, an anti-PD-L1 drug, and tremelimumab, an anti-CTLA-4 dr
Autor:
Daniel M. Halperin, Suyu Liu, Arvind Dasari, David Fogelman, Priya Bhosale, Armeen Mahvash, Jeannelyn S. Estrella, Laura Rubin, Ajaykumar C. Morani, Mark Knafl, Tim A. Overeem, Szu-Chin Fu, Luisa M. Solis, Edwin Parra Cuentas, Anuj Verma, Hong-Lei Chen, Swati Gite, Priya Subashchandrabose, Shannon Dervin, Katja Schulze, Walter C. Darbonne, Cindy Yun, Ignacio I. Wistuba, P. Andrew Futreal, Scott E. Woodman, James C. Yao
Publikováno v:
JAMA Oncol
IMPORTANCE: Therapies for patients with advanced well-differentiated neuroendocrine tumors (NETs) have expanded but remain inadequate, with patients dying of disease despite recent advances in NET therapy. While patients with other cancers have seen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dddac8d2ce3b68691ad8b930d043467
https://europepmc.org/articles/PMC8990358/
https://europepmc.org/articles/PMC8990358/
Autor:
Veena, Kochat, Ayush T, Raman, Sharon M, Landers, Ming, Tang, Jonathan, Schulz, Christopher, Terranova, Jace P, Landry, Angela D, Bhalla, Hannah C, Beird, Chia-Chin, Wu, Yingda, Jiang, Xizeng, Mao, Rossana, Lazcano, Swati, Gite, Davis R, Ingram, Min, Yi, Jianhua, Zhang, Emily Z, Keung, Christopher P, Scally, Christina L, Roland, Kelly K, Hunt, Barry W, Feig, P Andrew, Futreal, Patrick, Hwu, Wei-Lien, Wang, Alexander J, Lazar, John M, Slopis, Heather, Wilson-Robles, Dominique J, Wiener, Ian E, McCutcheon, Brandan, Wustefeld-Janssens, Kunal, Rai, Keila E, Torres
Publikováno v:
Acta neuropathologica. 142(3)
Malignant peripheral nerve sheath tumors (MPNSTs) are soft tissue sarcomas that frequently harbor genetic alterations in polycomb repressor complex 2 (PRC2) components-SUZ12 and EED. Here, we show that PRC2 loss confers a dedifferentiated early neura