Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Swathi U Lekshmi"'
Autor:
B R Vijaykumar, R Sai Kant, C Rajendran, Swathi U Lekshmi, Sundar Keerthana, Anita Mahadevan, S K Shankar, R S Jayshree
Publikováno v:
Annals of Indian Academy of Neurology, Vol 21, Iss 4, Pp 250-255 (2018)
Context: Published data on genetic characterization of Toxoplasma gondii (T.gondii) from clinical cases of toxoplasmosis from India is lacking. Aims: The present study was aimed at identifying genetic types of T. gondii in fatal cases of cerebral tox
Externí odkaz:
https://doaj.org/article/d2c63387c1d045048443e245f4eb2620
Autor:
Sai Kant R, Lakshmaiah K.C, Swathi U. Lekshmi, Keerthana Sundar, L. Appaji, R. S. Jayshree, Chellaiah Rajendran, B.R. Vijaykumar
Publikováno v:
Journal of Evidence Based Medicine and Healthcare, Vol 4, Iss 83, Pp 4894-4899 (2017)
BACKGROUND Toxoplasma gondii (T. gondii) is considered to be an important opportunistic pathogen in immunocompromised patients. After the advent of highly-activated antiretroviral therapy, though the frequency of opportunistic toxoplasmosis in the de
Autor:
Mohammed Takhi, Sarah Joseph, Noorsaadah Abd Rahman, Krishnamurthy N. Rao, Sheila Nathan, Kandepu Sreenivas, Swathi U. Lekshmi, Murali Ramachandra, Thomas Antony, Rohana Yusof, Ming Seong Lau, Hosahalli Subramanya, Anirudha Lakshminarasimhan
Publikováno v:
Protein Science. 24:832-840
Melioidosis is a tropical bacterial infection caused by Burkholderia pseudomallei (B. pseudomallei; Bpm), a Gram-negative bacterium. Current therapeutic options are largely limited to trimethoprim-sulfamethoxazole and β-lactam drugs, and the treatme
Autor:
Swathi U. Lekshmi, Smreti Vasudevan, Suparna Sengupta, Thankayyan R. Santhoshkumar, Reshma Thamkachy, Sannu Ann Thomas, Kallikat N. Rajasekharan
Publikováno v:
Apoptosis. 18:713-726
Mitochondria mediated signalling is the more common way of apoptosis induction exhibited by many chemotherapeutic agents in cancer cells. Death receptor mediated signalling for apoptosis in many cells also requires further amplification from the mito
Autor:
Swathi U. Lekshmi, R. S. Jayshree, R. Sai Kant, Chellaiah Rajendran, Anita Mahadevan, S K Shankar, B.R. Vijaykumar, D. Vaigundan
Publikováno v:
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases. 39
Toxoplasma gondii (T.gondii) infection can be devastating in the immunodeficient causing high morbidity and mortality. Due to limited availability of both diagnostic facilities and Highly Active Antiretroviral Therapy (HAART), toxoplasmosis continues
Autor:
Mathan Sankaran, James Alexis Platts, Chokkalingam Uvarani, Sengupta Suparna, Kumarasamy Chandraprakash, Swathi U. Lekshmi, Palathurai Subramaniam Mohan
Publikováno v:
Molecular diversity. 18(2)
An expedient route toward the synthesis of 4-hydroxyquinolone grafted spiropyrrolidines or pyrrolizidines has been accomplished through 1,3-dipolar cycloaddition reaction of various azomethine ylides derived from isatin or acenaphthalene and sarcosin
Autor:
Swathi U. Lekshmi, Bhavya Balan Chandrika, Sathish Kumar Maney, Santhoshkumar Thankayyan Retnabhai
Publikováno v:
The international journal of biochemistrycell biology. 42(12)
Overexpression of anti-apoptotic Bcl2 family proteins is often seen in cancers rendering them insensitive to apoptosis inducing anticancer strategies. Anti-apoptotic Bcl2 family proteins are associated with different organelles like mitochondria and
Autor:
Bhavya Balan Chandrika, Mahendra Seervi, T.R. Santhoshkumar, Sathish Kumar Maney, Jeena Joseph, Swathi U. Lekshmi, K S Praveen
Publikováno v:
Biochemical pharmacology. 79(11)
Tumors often acquire drug resistance due to functional loss of pro apoptotic gene Bax, a critical and essential component of cell death rendering them insensitive to most anti-tumor agents. Compounds that can induce Bax independent apoptotic cell dea