Výsledky vyhledávání - "Swathi Ramaraju"

Modeling the interface between islet amyloid polypeptide and insulin-based aggregation inhibitors: correlation to aggregation kinetics and membrane damage

Autor: Deborah L. Heyl, Joshua M. Osborne, Ranadheer Reddy Pesaru, M.C. Milletti, Hector Figueroa, Swathi Ramaraju, Durgaprasad Peddi, Brenan M. Wilson, Balakrishna Kurva

Publikováno v: Journal of chemical information and modeling. 52(5)

Human islet amyloid polypeptide (hIAPP) forms cytotoxic fibrils in type-2 diabetes and insulin is known to inhibit formation of these aggregates. In this study, a series of insulin-based inhibitors were synthesized and assessed for their ability to s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38d110717997ced0d5f0df251d8d32ae
https://pubmed.ncbi.nlm.nih.gov/22554091

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