Výsledky vyhledávání - "Swarnima Joshi"

Akademický článek

Mutation of a serine near the catalytic site of the choline acetyltransferase a gene almost completely abolishes motility of the zebrafish embryo.

Autor: Swarnima Joshi, Sanamjeet Virdi, Christelle Etard, Robert Geisler, Uwe Strähle

Publikováno v: PLoS ONE, Vol 13, Iss 11, p e0207747 (2018)

In zebrafish, the gene choline acetyltransferase a (chata) encodes one of the two ChAT orthologs responsible for the synthesis of acetylcholine. Acetylcholine (ACh) is essential for neuromuscular transmission and its impaired synthesis by ChAT can le

Externí odkaz: https://doaj.org/article/a5d3d24de899472d854ba58884ceb177

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Tracking of Indels by DEcomposition is a Simple and Effective Method to Assess Efficiency of Guide RNAs in Zebrafish

Autor: Christelle Etard, Ralf Mikut, Swarnima Joshi, Johannes Stegmaier, Uwe Strähle

Publikováno v: Zebrafish. 14(6)

A bottleneck in CRISPR/Cas9 genome editing is variable efficiencies of in silico-designed gRNAs. We evaluated the sensitivity of the TIDE method (Tracking of Indels by DEcomposition) introduced by Brinkman et al. in 2014 for assessing the cutting eff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c6ca84bec4c16c0644190da7bf2399d
https://pubmed.ncbi.nlm.nih.gov/28767326

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Mutation of a serine near the catalytic site of the choline acetyltransferase a gene almost completely abolishes motility of the zebrafish embryo

Autor: Robert Geisler, Christelle Etard, Swarnima Joshi, Uwe Strähle, Sanamjeet Virdi

Publikováno v: PLOS ONE, 13 (11), e0207747
PLoS ONE, Vol 13, Iss 11, p e0207747 (2018)
PLoS ONE
PLOS ONE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4e1c08c18b8f4c31f27c060583be997
https://doi.org/10.1371/journal.pone.0207747

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