Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Swaraj Thaman"'
Autor:
Hwee Hui Lau, Nicole A. J. Krentz, Fernando Abaitua, Marta Perez-Alcantara, Jun-Wei Chan, Jila Ajeian, Soumita Ghosh, Yunkyeong Lee, Jing Yang, Swaraj Thaman, Benoite Champon, Han Sun, Alokkumar Jha, Shawn Hoon, Nguan Soon Tan, Daphne Su-Lyn Gardner, Shih Ling Kao, E. Shyong Tai, Anna L. Gloyn, Adrian Kee Keong Teo
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract The coding variant (p.Arg192His) in the transcription factor PAX4 is associated with an altered risk for type 2 diabetes (T2D) in East Asian populations. In mice, Pax4 is essential for beta cell formation but its role on human beta cell deve
Externí odkaz:
https://doaj.org/article/04c9903c45a041a292092f38195e3bde
Autor:
Katia K. Mattis, Nicole A. J. Krentz, Christoph Metzendorf, Fernando Abaitua, Aliya F. Spigelman, Han Sun, Jennifer M. Ikle, Swaraj Thaman, Antje K. Rottner, Austin Bautista, Eugenia Mazzaferro, Marta Perez-Alcantara, Jocelyn E. Manning Fox, Jason M. Torres, Agata Wesolowska-Andersen, Grace Z. Yu, Anubha Mahajan, Anders Larsson, Patrick E. MacDonald, Benjamin Davies, Marcel den Hoed, Anna L. Gloyn
Publikováno v:
Diabetologia. 66:674-694
Aims/hypothesis Genome-wide studies have uncovered multiple independent signals at the RREB1 locus associated with altered type 2 diabetes risk and related glycaemic traits. However, little is known about the function of the zinc finger transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84fa56621fef9812409ed7ea80259057
https://doi.org/10.1007/s00125-022-05856-6
https://doi.org/10.1007/s00125-022-05856-6
Autor:
Mahesh M Umapathysivam, Elisa Araldi, Benoit Hastoy, Adem Y Dawed, Hasan Vatandaslar, Shahana Sengupta, Adrian Kaufmann, Søren Thomsen, Bolette Hartmann, Anna E Jonsson, Hasan Kabakci, Swaraj Thaman, Niels Grarup, Christian T Have, Kristine Færch, Anette P Gjesing, Sameena Nawaz, Jane Cheeseman, Matthew J Neville, Oluf Pedersen, Mark Walker, Christopher Jennison, Andrew T Hattersley, Torben Hansen, Fredrik Karpe, Jens J Holst, Angus G Jones, Michael Ristow, Mark I McCarthy, Ewan R Pearson, Markus Stoffel, Anna L Gloyn
Patients with type 2 diabetes vary in their response to currently available therapeutic agents (including GLP-1 receptor agonists) leading to suboptimal glycemic control and increased risk of complications. We show that human carriers of hypomorphic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::157451176660a0e343840228d18dc298
https://doi.org/10.1101/2023.04.07.23288197
https://doi.org/10.1101/2023.04.07.23288197
