Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Swapnil Tichkule"'
Autor:
Qiao Su, Louise Baker, Samantha Emery, Balu Balan, Brendan Ansell, Swapnil Tichkule, Ivo Mueller, Staffan G. Svärd, Aaron Jex
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 22, Iss , Pp 9-19 (2023)
Benzimidazole-2-carbamates (BZ, e.g., albendazole; ALB), which bind β-tubulin to disrupt microtubule polymerization, are one of two primary compound classes used to treat giardiasis. In most parasitic nematodes and fungi, BZ-resistance is caused by
Externí odkaz:
https://doaj.org/article/4dc27df364234738957f70e47311917c
Autor:
Samantha J. Emery-Corbin, Qiao Su, Swapnil Tichkule, Louise Baker, Ernest Lacey, Aaron R. Jex
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 16, Iss , Pp 162-173 (2021)
Benzimidazole-2-carbamate (BZ) compounds, including Albendazole (Alb), are one of just two drug classes approved to treat the gastrointestinal protist Giardia duodenalis. Benzimidazoles bind to the tubulin dimer interface overlapping the colchicine b
Externí odkaz:
https://doaj.org/article/4615c63208d94277b239d43239b2c1db
Autor:
Swapnil Tichkule, Ernest Lacey, Qiao Su, Louise Baker, Aaron R. Jex, Samantha J. Emery-Corbin
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 16, Iss, Pp 162-173 (2021)
International Journal for Parasitology: Drugs and Drug Resistance
International Journal for Parasitology: Drugs and Drug Resistance
Benzimidazole-2-carbamate (BZ) compounds, including Albendazole (Alb), are one of just two drug classes approved to treat the gastrointestinal protist Giardia duodenalis. Benzimidazoles bind to the tubulin dimer interface overlapping the colchicine b
Autor:
Swapnil Tichkule, Yoochan Myung, Myo T Naung, Brendan R E Ansell, Andrew J Guy, Namrata Srivastava, Somya Mehra, Simone M Cacciò, Ivo Mueller, Alyssa E Barry, Cock van Oosterhout, Bernard Pope, David B Ascher, Aaron R Jex
Publikováno v:
Molecular biology and evolution. 39(9)
Large-scale comparative genomics- and population genetic studies generate enormous amounts of polymorphism data in the form of DNA variants. Ultimately, the goal of many of these studies is to associate genetic variants to phenotypes or fitness. We i
Autor:
Giulia I. Corsi, Swapnil Tichkule, Anna Rosa Sannella, Paolo Vatta, Francesco Asnicar, Nicola Segata, Aaron R. Jex, Cock van Oosterhout, Simone M. Cacciò
Publikováno v:
Corsi, G I, Tichkule, S, Sannella, A R, Vatta, P, Asnicar, F, Segata, N, Jex, A R, van Oosterhout, C & Cacciò, S M 2023, ' Recent genetic exchanges and admixture shape the genome and population structure of the zoonotic pathogen Cryptosporidium parvum ', Molecular Ecology, vol. 32, no. 10, pp. 2633-2645 . https://doi.org/10.1111/mec.16556
Cryptosporidium parvum is a globally distributed zoonotic pathogen and a major cause of diarrhoeal disease in humans and ruminants. The parasite's life cycle comprises an obligatory sexual phase, during which genetic exchanges can occur between previ
Autor:
Alan John, Stefanie M. Bader, Niccolay Madiedo Soler, Kharizta Wiradiputri, Swapnil Tichkule, Sean T. Smyth, Stuart A. Ralph, Aaron R. Jex, Nichollas E. Scott, Christopher J. Tonkin, Ethan D. Goddard-Borger
Publikováno v:
Journal of Biological Chemistry. 299:103006
Autor:
Swapnil Tichkule, Simone M. Cacciò, Guy Robinson, Rachel M. Chalmers, Ivo Mueller, Samantha J. Emery-Corbin, Daniel Eibach, Kevin M. Tyler, Cock van Oosterhout, Aaron R. Jex
Publikováno v:
Molecular biology and evolution. 39(4)
Cryptosporidiosis is a major global health problem and a primary cause of diarrhea, particularly in young children in low- and middle-income countries (LMICs). The zoonotic Cryptosporidium parvum and anthroponotic Cryptosporidium hominis cause most h
Autor:
C. van Oosterhout, Simone M. Cacciò, Y. Myung, Swapnil Tichkule, Alyssa E. Barry, M. T. Naung, Guy Aj, Brendan R E Ansell, Somya Mehra, Aaron R. Jex, D. B. Ascher, Ivo Mueller, Bernard J. Pope, N. Srivastava
Large-scale comparative genomics- and population genetic studies generate enormous amounts of polymorphism data in the form of DNA variants. Ultimately, the goal of many of these studies is to associate genetic variants to phenotypes or fitness. We i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3a088bc24b8dbe274cf0886406a5f83
https://doi.org/10.1101/2021.11.16.468904
https://doi.org/10.1101/2021.11.16.468904
Autor:
P. Vatta, A. R. Sannella, Cock van Oosterhout, F. Asnicar, Aaron R. Jex, Nicola Segata, G. I. Corsi, Simone M. Cacciò, Swapnil Tichkule
Cryptosporidium parvum is a global zoonoses and a major cause of diarrhoea in humans and ruminants. The parasite’s life cycle comprises an obligatory sexual phase, during which genetic exchanges can occur between previously isolated lineages. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de033415caa855ad3d1cfba25410a54d
https://doi.org/10.1101/2021.10.15.464618
https://doi.org/10.1101/2021.10.15.464618
Autor:
Samantha J. Emery-Corbin, Rachel M. Chalmers, Simone M. Cacciò, Ivo Mueller, Guy Robinson, Cock van Oosterhout, Kevin M. Tyler, Swapnil Tichkule, Daniel Eibach, Aaron R. Jex
Cryptosporidiosis is a major global health problem and a primary cause of diarrhoea, particularly in young children in low- and middle-income countries (LMICs). The zoonoticCryptosporidium parvumand anthroponoticC. hominiscause most human infections.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c56eb0b0dd39dc23e0873a3b20839e
https://doi.org/10.1101/2021.09.09.459610
https://doi.org/10.1101/2021.09.09.459610