Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Swapnil K Sonkusare"'
Autor:
Zdravka Daneva, Matteo Ottolini, Yen Lin Chen, Eliska Klimentova, Maniselvan Kuppusamy, Soham A Shah, Richard D Minshall, Cheikh I Seye, Victor E Laubach, Brant E Isakson, Swapnil K Sonkusare
Publikováno v:
eLife, Vol 10 (2021)
Pannexin 1 (Panx1), an ATP-efflux pathway, has been linked with inflammation in pulmonary capillaries. However, the physiological roles of endothelial Panx1 in the pulmonary vasculature are unknown. Endothelial transient receptor potential vanilloid
Externí odkaz:
https://doaj.org/article/4e52c48d21c241c0a4496dbc4db01f8d
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-13 (2024)
Abstract The success of lung transplantation is limited by the high rate of primary graft dysfunction due to ischemia-reperfusion injury (IRI). Lung IRI is characterized by a robust inflammatory response, lung dysfunction, endothelial barrier disrupt
Externí odkaz:
https://doaj.org/article/fbd37829100a471980e44bfbb336bf22
Autor:
Claire A. Ruddiman, Richard Peckham, Melissa A. Luse, Yen-Lin Chen, Maniselvan Kuppusamy, Bruce A. Corliss, P. Jordan Hall, Chien-Jung Lin, Shayn M. Peirce, Swapnil K. Sonkusare, Robert P. Mecham, Jessica E. Wagenseil, Brant E. Isakson
Publikováno v:
JCI Insight, Vol 8, Iss 9 (2023)
Lipid regulation of ion channels is largely explored using in silico modeling with minimal experimentation in intact tissue; thus, the functional consequences of these predicted lipid-channel interactions within native cellular environments remain el
Externí odkaz:
https://doaj.org/article/7e3053ea3fba4f4ebcd0e85d89274a84
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/80a84eea716a4df0b9192532ac4a4be3
Autor:
Zdravka Daneva, Yen‐Lin Chen, Huy Q. Ta, Vamsi Manchikalapudi, Abhishek Bazaz, Victor E. Laubach, Swapnil K. Sonkusare
Publikováno v:
Pulmonary Circulation, Vol 13, Iss 1, Pp n/a-n/a (2023)
Abstract Endothelial cells (ECs) from small pulmonary arteries (PAs) release nitric oxide (NO) and prostacyclin, which lower pulmonary arterial pressure (PAP). In pulmonary hypertension (PH), the levels of endothelium‐derived NO and prostacyclin ar
Externí odkaz:
https://doaj.org/article/ed72a83138984a83b11cf07c8e9401ae
Autor:
Yen‐Lin Chen, Swapnil K. Sonkusare
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 4 (2022)
Externí odkaz:
https://doaj.org/article/757b45bf40b04eaf8da5c7762dc8d652
Autor:
Doris Wong, Gaëlle Auguste, Christian L. Lino Cardenas, Adam W. Turner, Yixuan Chen, Yipei Song, Lijiang Ma, R. Noah Perry, Redouane Aherrahrou, Maniselvan Kuppusamy, Chaojie Yang, Jose Verdezoto Mosquera, Collin J. Dube, Mohammad Daud Khan, Meredith Palmore, Jaspreet Kalra, Maryam Kavousi, Patricia A. Peyser, Ljubica Matic, Ulf Hedin, Ani Manichaikul, Swapnil K. Sonkusare, Mete Civelek, Jason C. Kovacic, Johan L.M. Björkegren, Rajeev Malhotra, Clint L. Miller
Publikováno v:
Circulation Research, 132(9), 1144-1161. Lippincott Williams & Wilkins
Background: Genome-wide association studies have identified hundreds of loci associated with common vascular diseases, such as coronary artery disease, myocardial infarction, and hypertension. However, the lack of mechanistic insights for many GWAS l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fe5ac5ce89e69f5b733b655149c1b64
https://doi.org/10.1161/CIRCRESAHA.122.321692
https://doi.org/10.1161/CIRCRESAHA.122.321692
Autor:
Yen-Lin, Chen, Zdravka, Daneva, Maniselvan, Kuppusamy, Matteo, Ottolini, Thomas M, Baker, Eliska, Klimentova, Soham A, Shah, Jennifer D, Sokolowski, Min S, Park, Swapnil K, Sonkusare
Publikováno v:
Circulation. 146(7)
CaWe used SMC-specific TRPV4We provide first evidence that TRPV4Our data identify novel smooth muscle Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f21253ef02eb1162ca3ad2a7a2e58387
https://pubmed.ncbi.nlm.nih.gov/35758040
https://pubmed.ncbi.nlm.nih.gov/35758040
Autor:
Yen-Lin Chen, Zdravka Daneva, Maniselvan Kuppusamy, Matteo Ottolini, Thomas M. Baker, Eliska Klimentova, Soham A. Shah, Jennifer D. Sokolowski, Min S. Park, Swapnil K. Sonkusare
Publikováno v:
Circulation. 146:548-564
Background: Ca 2+ signals in smooth muscle cells (SMCs) contribute to vascular resistance and control blood pressure. Increased vascular resistance in hypertension has been attributed to impaired SMC Ca 2+ signaling mechanisms. In this regard, transi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26614f4ba73a72ee6f6fbe5441d5ac24
https://doi.org/10.1161/circulationaha.121.058607
https://doi.org/10.1161/circulationaha.121.058607
Autor:
Kirsten Jander, Jan Greulich, Stefanie Gonnissen, Niloofar Ale-Agha, Christine Goy, Philipp Jakobs, Sabrina Farrokh, Corina Marziano, Swapnil K. Sonkusare, Judith Haendeler, Joachim Altschmied
Publikováno v:
Antioxidants, Vol 10, Iss 3, p 428 (2021)
We previously demonstrated that the transcription factor Grainyhead-like 3 (GRHL3) has essential functions in endothelial cells by inhibiting apoptosis and promoting migration as well as activation of endothelial nitric oxide synthase (eNOS). We now
Externí odkaz:
https://doaj.org/article/cacda6784fe64f48b1f84bf0b3dd054e