Zobrazeno 1 - 10 of 16 pro vyhledávání: '"Swapnil D. Jadhav"'
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Akademický článek
Pharmacophore modeling and 3D QSAR studies of aryl amine derivatives as potential lumazine synthase inhibitors
Autor: Manish S. Bhatia, Krishna D. Pakhare, Prafulla B. Choudhari, Swapnil D. Jadhav, Rakesh P. Dhavale, Neela M. Bhatia
Publikováno v: Arabian Journal of Chemistry, Vol 10, Iss S1, Pp S100-S104 (2017)
Design and discovery of novel antifungal compounds is the need of time, more than ever before due to the unavailability of effective antifungal therapy to treat resistant fungal infections. Due to morphological and functional similarities of fungi bo
Externí odkaz: https://doaj.org/article/c340560a25bc4585a703380b9c91a295
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2
In silico design, synthesis, characterization and pharmacological evaluation of captopril conjugates in the treatment of renal fibrosis
Autor: Prafulla B. Choudhari, Swapnil D. Jadhav, Manish S. Bhatia
Publikováno v: New Journal of Chemistry. 43:504-513
Renal fibrosis is a renal disorder whereby production of excess fibrous connective tissue in the glomerulus and proximal convoluted tubules will occur in a reparative or reactive process leading to severe conditions like surgery, replacement, etc. Su
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c3aa1914e9075586212e7c206d681c08
https://doi.org/10.1039/c8nj03836h
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3
Gel permeation chromatographic method for drug protein binding studies
Autor: Manish S. Bhatia, Santosh S. Kumbhar, Swapnil D. Jadhav
Publikováno v: Marmara Pharmaceutical Journal. 21:938-948
The estimation of individual plasma protein in free and bound form with analytes has importance in pharmacokinetics study. Albumins and globulins are most abundantly found in plasma and plays crucial role in plasma protein binding. The present commun
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0c0020e02ee00b4a86443a6534678b1d
https://doi.org/10.12991/mpj.2017.17
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4
Design and development of potent and selective factor IXa inhibitors
Autor: Vinod L. Gaikwad, Kundan B. Ingale, Manish S. Bhatia, Prafulla B. Choudhari, Santosh S. Kumbhar, Swapnil D. Jadhav
Publikováno v: Journal of the Taiwan Institute of Chemical Engineers. 68:130-135
Clotting factors are important serine proteases present in body regulating both intrinsic and extrinsic pathways of blood coagulation. Factor IX which is also known as Christmas factor which is activated form of factor IXa involved in the intrinsic p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cbad510d78fde450da79575695db5337
https://doi.org/10.1016/j.jtice.2016.09.036
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5
Pharmacophore modeling and 3D QSAR studies of aryl amine derivatives as potential lumazine synthase inhibitors
Autor: Krishna D. Pakhare, Prafulla B. Choudhari, Neela M. Bhatia, Rakesh P. Dhavale, Swapnil D. Jadhav, Manish S. Bhatia
Publikováno v: Arabian Journal of Chemistry, Vol 10, Iss S1, Pp S100-S104 (2017)
Design and discovery of novel antifungal compounds is the need of time, more than ever before due to the unavailability of effective antifungal therapy to treat resistant fungal infections. Due to morphological and functional similarities of fungi bo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ce6aa48f695f469dfa7fde62ca5077f
http://www.sciencedirect.com/science/article/pii/S1878535212001657
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6
Synthesis and characterization of norverapamil and quantification of verapamil and nor-verapamil in plasma
Autor: Parag A Pathade, Manish S. Bhatia, Prafulla B. Choudhari, Harinath N. More, Swapnil D. Jadhav, Neela M. Bhatia
Publikováno v: Journal of Analytical Chemistry. 68:924-930
Verapamil is a calcium channel blocking agent which has found widespread use in the management of supraventricular tachyarrhythmias, angina pectoris, hypertrophic cardiomyopathy and hypertension. It is converted to its biologically active metabolite
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::98e8569e2a3fc8dc8535d014c5590ec8
https://doi.org/10.1134/s1061934813100031
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8
Pharmacophore Modelling, Quantitative Structure Activity Relationship (QSAR) and Docking Studies of Pyrimidine Analogs as Potential Calcium Channel Blockers
Autor: Manish S. Bhatia, Swapnil D. Jadhav, Prafulla B. Choudhari
Publikováno v: Journal of the Korean Chemical Society. 57:99-103
The present communication deals with the Pharmacophore modeling, 3D QSAR and docking analysis on series of Pyrimidine derivatives as potential calcium channel blockers. The computational studies showed hydrogen bond donor, hydrogen bond acceptor, and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1b7ffcd53b5487dd6e99df01e20a3321
https://doi.org/10.5012/jkcs.2013.57.1.99
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9
Hyperoxaluria leads to dysbiosis and drives selective enrichment of oxalate metabolizing bacterial species in recurrent kidney stone endures
Autor: Shrikant S. Bhute, Manish S. Bhatia, Mangesh V. Suryavanshi, Swapnil D. Jadhav, Rahul P. Gune, Yogesh S. Shouche
Publikováno v: Scientific Reports
Hyperoxaluria due to endogenously synthesized and exogenously ingested oxalates is a leading cause of recurrent oxalate stone formations. Even though, humans largely rely on gut microbiota for oxalate homeostasis, hyperoxaluria associated gut microbi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa94063d2a02aacfd59a918e2b9e85c8
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