Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Swapna S. Vemula"'
Autor:
Christina L. Zheng, Nicholas J. Wang, Jongsuk Chung, Homayoun Moslehi, J. Zachary Sanborn, Joseph S. Hur, Eric A. Collisson, Swapna S. Vemula, Agne Naujokas, Kami E. Chiotti, Jeffrey B. Cheng, Hiva Fassihi, Andrew J. Blumberg, Celeste V. Bailey, Gary M. Fudem, Frederick G. Mihm, Bari B. Cunningham, Isaac M. Neuhaus, Wilson Liao, Dennis H. Oh, James E. Cleaver, Philip E. LeBoit, Joseph F. Costello, Alan R. Lehmann, Joe W. Gray, Paul T. Spellman, Sarah T. Arron, Nam Huh, Elizabeth Purdom, Raymond J. Cho
Publikováno v:
Cell Reports, Vol 9, Iss 4, Pp 1228-1234 (2014)
Somatic mutations in cancer are more frequent in heterochromatic and late-replicating regions of the genome. We report that regional disparities in mutation density are virtually abolished within transcriptionally silent genomic regions of cutaneous
Externí odkaz:
https://doaj.org/article/4bc447746133449a9b036da17031b264
Autor:
Alessio Giubellino, Sheilagh Maguiness, Timothy H. McCalmont, Iwei Yeh, Swapna S. Vemula, Boris C. Bastian, Simon F. Roy
Publikováno v:
Pigment cell & melanoma research, vol 34, iss 5
Pigment Cell Melanoma Res
Pigment Cell Melanoma Res
Patients with non-supernumerary ring chromosome 7 syndrome have an increased incidence of hemangiomas, cafe-au-lait spots, and melanocytic nevi. The mechanism for the increased incidence of these benign neoplasms is unknown. We present the case of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ca49c5eeca87aa4f9d0f98e129a7239
https://escholarship.org/uc/item/9004v1h4
https://escholarship.org/uc/item/9004v1h4
Autor:
Takeshi Isoyama, Maria C. Garrido, Alexander Gagnon, Boris C. Bastian, Kenji Nakamaru, A. Hunter Shain, Timothy H. McCalmont, Thomas Botton, Iwei Yeh, Philip E. LeBoit, Swapna S. Vemula, Meng Kian Tee, Alyssa J. Sparatta
Publikováno v:
The Journal of Pathology. 240:282-290
Oncogenic fusions in TRK family receptor tyrosine kinases have been identified in several cancers and can serve as therapeutic targets. We identified ETV6-NTRK3, MYO5A-NTRK3 and MYH9-NTRK3 fusions in Spitz tumours, and demonstrated that NTRK3 fusions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29b244135d449faad29045b5130c245a
https://doi.org/10.1002/path.4775
https://doi.org/10.1002/path.4775
Autor:
Richard Yu, Shanshan Liu, Jingly F. Weier, Boris C. Bastian, Steffen Heegaard, Jens Folke Kiilgaard, Karin Wadt, Mette Bagger, A. Hunter Shain, Darwin Chang, Swapna S. Vemula
Publikováno v:
Nature genetics
Nature genetics, vol 51, iss 7
Nature genetics, vol 51, iss 7
Uveal melanoma is a clinically distinct and particularly lethal subtype of melanoma originating from melanocytes in the eye. Here, we performed multi-region DNA sequencing of primary uveal melanomas and their matched metastases from 35 patients. We o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::093704f2466d4da7d378748cc422c5a0
https://pubmed.ncbi.nlm.nih.gov/31253977
https://pubmed.ncbi.nlm.nih.gov/31253977
Autor:
Iwei Yeh, Swapna S. Vemula, Maria C. Garrido, Arnaud de la Fouchardière, Klaus J. Busam, Daniel Pissaloux, Thaddeus W. Mully, Timothy H. McCalmont, Boris C. Bastian, Philip E. LeBoit
Publikováno v:
The American journal of surgical pathology, vol 39, iss 5
Activating kinase fusions have recently been described as early oncogenic events that are mutually exclusive with HRAS and BRAF mutations in Spitz tumors. Here, we report a series of 32 Spitz tumors with ALK fusions (6 Spitz nevi, 22 atypical Spitz t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6ef5ff31d24d7a7db17282bfa477bb9
https://doi.org/10.1097/pas.0000000000000387
https://doi.org/10.1097/pas.0000000000000387
Autor:
Swapna S. Vemula, Philip E. LeBoit, Andrea Saggini, Jingly F. Weier, Sonia A. Mirza, Yann Charli-Joseph
Publikováno v:
Journal of the American Academy of Dermatology. 71:1127-1136
Background Perivascular epithelioid cell tumor (PEComa) is a rare neoplasm of uncertain histogenesis with a mixed myomelanocytic immunophenotype, rarely arising in the skin (primary cutaneous PEComa [pcPEComa]). Objective We analyzed the clinicopatho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4abbf451ff71482e748cb387e43f7220
https://doi.org/10.1016/j.jaad.2014.08.016
https://doi.org/10.1016/j.jaad.2014.08.016
Autor:
Nam Huh, Andrew J. Blumberg, Eric A. Collisson, Jongsuk Chung, Joe W. Gray, Christina Zheng, Isaac M. Neuhaus, Frederick G. Mihm, Jeffrey B. Cheng, Joseph S. Hur, Alan R. Lehmann, Joseph F. Costello, Agne Naujokas, Homayoun Moslehi, Gary M. Fudem, Hiva Fassihi, Swapna S. Vemula, J. Zachary Sanborn, James E. Cleaver, Bari B. Cunningham, Raymond J. Cho, Celeste V. Bailey, Sarah T. Arron, Wilson Liao, Philip E. LeBoit, Kami E. Chiotti, Dennis H. Oh, Paul T. Spellman, Elizabeth Purdom, Nicholas J. Wang
Publikováno v:
Zheng, CL; Wang, NJ; Chung, J; Moslehi, H; Sanborn, JZ; Hur, JS; et al.(2014). Transcription Restores DNA Repair to Heterochromatin, Determining Regional Mutation Rates in Cancer Genomes. Cell Reports, 9(4), 1228-1234. doi: 10.1016/j.celrep.2014.10.031. UCSF: Retrieved from: http://www.escholarship.org/uc/item/3th2t2tm
Cell reports, vol 9, iss 4
Cell Reports, Vol 9, Iss 4, Pp 1228-1234 (2014)
Cell reports, vol 9, iss 4
Cell Reports, Vol 9, Iss 4, Pp 1228-1234 (2014)
© 2014 The Authors. Somatic mutations in cancer are more frequent in heterochromatic and late-replicating regions of the genome. We report that regional disparities in mutation density are virtually abolished within transcriptionally silent genomic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13187b522fc4192b7ef8967b8d4d4d05
Autor:
Yann Charli-Joseph, Leona A. Doyle, Andrea Saggini, Jingly F. Weier, Philip E. LeBoit, Christopher D.M. Fletcher, Swapna S. Vemula, Sonia A. Mirza
Publikováno v:
Journal of the American Academy of Dermatology. 71:256-263
Background Cutaneous fibrous histiocytoma (FH) is a common mesenchymal neoplasm. Metastasis is rare, disproportionately occurring among the aneurysmal, cellular, atypical, and deep variants. Objective We determined whether DNA copy number changes occ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34ea95785bbea00a4e002f29bd34eb3a
https://doi.org/10.1016/j.jaad.2014.03.015
https://doi.org/10.1016/j.jaad.2014.03.015
Autor:
Michelle B. Crosby, Raya Khanin, Klaus G. Griewank, Adriana Heguy, Igor Dolgalev, Joan M. O'Brien, Catherine D. Van Raamsdonk, Michael R. Speicher, Thomas Wiesner, Ritu Roy, M. Mert Sozen, Werner Wackernagel, Swapna S. Vemula, Gail Baimukanova, Anna C. Obenauf, Klaus J. Busam, Boris C. Bastian, Gary G. R. Green, Nancy Bouvier, Maria C. Garrido
Publikováno v:
New England Journal of Medicine; Vol 363
BACKGROUND Uveal melanoma is the most common intraocular cancer. There are no effective therapies for metastatic disease. Mutations in GNAQ, the gene encoding an alpha subunit of heterotrimeric G proteins, are found in 40% of uveal melanomas. METHODS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::714b0026112b09cab1c3f714e27f05ec
Autor:
Iwei Yeh, Philip E. LeBoit, Timothy H. McCalmont, Sonia A. Mirza, Swapna S. Vemula, Thomas Wiesner, Boris C. Bastian, Alyssa J. Sparatta, Thaddeus W. Mully
Publikováno v:
The American journal of surgical pathology, vol 38, iss 8
Germline loss of function mutations in BAP1 are associated with the development of cutaneous melanocytic tumors with some histopathologic characteristics seen in Spitz nevi. Similar melanocytic tumors occurring in a sporadic setting have been demonst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4228f162d71d4dd3eed8cef985f0733
https://pubmed.ncbi.nlm.nih.gov/25871468
https://pubmed.ncbi.nlm.nih.gov/25871468