Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Swapna Kollu"'
Publikováno v:
Stem Cell Reports, Vol 4, Iss 6, Pp 1061-1074 (2015)
To ensure accurate genomic segregation, cells evolved the spindle assembly checkpoint (SAC), whose role in adult stem cells remains unknown. Inducible perturbation of a SAC kinase, Mps1, and its downstream effector, Mad2, in skeletal muscle stem cell
Externí odkaz:
https://doaj.org/article/0c71acc5f0584be8bbb8ddbd6d45003a
Autor:
Chandreyee Datta, Samuel S. Truesdell, Keith Q. Wu, Syed I. A. Bukhari, Harrison Ngue, Brienna Buchanan, Olivier Le Tonqueze, Sooncheol Lee, Swapna Kollu, Madeleine A. Granovetter, Myriam Boukhali, Johannes Kreuzer, Maheen S. Batool, Leonora Balaj, Wilhelm Haas, Shobha Vasudevan
Publikováno v:
Science Advances. 8
Quiescent leukemic cells survive chemotherapy, with translation changes. Our data reveal that FXR1, a protein amplified in several aggressive cancers, is elevated in quiescent and chemo-treated leukemic cells and promotes chemosurvival. This suggests
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d40584a391f5eb87fe97400e4dd9c82e
https://doi.org/10.1126/sciadv.abo1304
https://doi.org/10.1126/sciadv.abo1304
Autor:
David T. Scadden, Isabel Beerman, Xuefeng Sun, Colin Crist, Annarita Scaramozza, Charles P. Lin, Swapna Kollu, Andrew S. Brack, Dongsu Park, Derrick J. Rossi
Publikováno v:
Cell stem cell, vol 24, iss 6
Stem cell heterogeneity is recognized as functionally relevant for tissue homeostasis and repair. The identity, context dependence, and regulation of skeletal muscle satellite cell (SC) subsets remains poorly understood. We identify a minor subset of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0379a85327ec9a58eb99afd26a050a78
https://escholarship.org/uc/item/7wg81139
https://escholarship.org/uc/item/7wg81139
Autor:
Shobha Vasudevan, O Le Tonqueze, Samuel S. Truesdell, Swapna Kollu, M Al-Salah, Sooncheol Lee
Publikováno v:
Cell Cycle. 15:1874-1882
FXR1 belongs to a family of RNA-binding proteins that play critical roles in post-transcriptional regulation of gene expression in immunity, development and cancer. FXR1 is associated with regulation of specific mRNAs in myocytes and macrophages. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::558c17508a524839f2d4d698392c4cf8
https://doi.org/10.1080/15384101.2016.1189040
https://doi.org/10.1080/15384101.2016.1189040
Autor:
Esha Jain, Roopali Gandhi, David A. Sweetser, Adam Langenbucher, Myriam Boukhali, Shobha Vasudevan, Nicholas J Haradhwala, Akiko Yanagiya, Swapna Kollu, Syed I. A. Bukhari, Ruslan I. Sadreyev, Michael S. Lawrence, Wilhelm Haas, Sooncheol Lee, Radhika Raheja, Maria Antonietta Mazzola, Samuel S. Truesdell, Richard M. Mortensen, Dongjun Lee
Publikováno v:
Molecular Cancer Research. 18:B32-B32
Quiescent (G0) cells are a clinically relevant fraction in cancers, which include dormant cancer stem cells, and resist clinical therapy. G0 cells reveal extensive changes in gene expression at the protein and translation levels. We previously identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb47cfded3054909a5248202c5fdc6d2
https://doi.org/10.1158/1557-3125.pi3k-mtor18-b32
https://doi.org/10.1158/1557-3125.pi3k-mtor18-b32
Publikováno v:
Stem Cell Reports, Vol 4, Iss 6, Pp 1061-1074 (2015)
Stem Cell Reports
Stem Cell Reports
Summary To ensure accurate genomic segregation, cells evolved the spindle assembly checkpoint (SAC), whose role in adult stem cells remains unknown. Inducible perturbation of a SAC kinase, Mps1, and its downstream effector, Mad2, in skeletal muscle s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f00a2c6bf3a3a539f0024cdd8c0fc6b2
https://doi.org/10.1016/j.stemcr.2015.04.006
https://doi.org/10.1016/j.stemcr.2015.04.006
Autor:
Shobha Vasudevan, Akiko Yanagiya, Myriam Boukhali, Ruslan I. Sadreyev, Syed I. A. Bukhari, Richard M. Mortensen, Anthony Classon, Samuel S. Truesdell, Swapna Kollu, Sooncheol Lee, Esha Jain, Wilhelm Haas
MicroRNAs predominantly decrease gene expression; however, specific mRNAs are translationally upregulated in quiescent (G0) mammalian cells and immature Xenopus laevis oocytes by an FXR1a-associated microRNA-protein complex (microRNP) that lacks the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::355098e98186b741627db289cf67fbe9
https://europepmc.org/articles/PMC4811377/
https://europepmc.org/articles/PMC4811377/
Publikováno v:
Biophysical Journal. 100:1756-1764
During cell division, chromosomes must faithfully segregate to maintain genome integrity, and this dynamic mechanical process is driven by the macromolecular machinery of the mitotic spindle. However, little is known about spindle mechanics. For exam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90467c021f693c6068973e9847c603d3
https://doi.org/10.1016/j.bpj.2011.02.017
https://doi.org/10.1016/j.bpj.2011.02.017
Autor:
Syed I. A. Bukhari, Ruslan I. Sadreyev, Wilhelm Haas, Esha Jain, Swapna Kollu, Akiko Yanagiya, Samuel S. Truesdell, Anthony Classon, Shobha Vasudevan, Sooncheol Lee, Myriam Boukhali, Richard M. Mortensen
Publikováno v:
Cancer Research. 77:4997-4997
Quiescence (G0) represents an assortment of reversible, cell cycle-arrested states that are resistant to unfavorable conditions and associated with cancer persistence. G0 involves regulated gene expression with selective mRNA expression and decreased
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8dff8d14562c95d5f687c89aafd3568
https://doi.org/10.1158/1538-7445.am2017-4997
https://doi.org/10.1158/1538-7445.am2017-4997