Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Swapan K. Dasgupta"'
Autor:
Tiffany Chern, Annita Achilleos, Xuefei Tong, Matthew C. Hill, Alexander B. Saltzman, Lucas C. Reineke, Arindam Chaudhury, Swapan K. Dasgupta, Yushi Redhead, David Watkins, Joel R. Neilson, Perumal Thiagarajan, Jeremy B. A. Green, Anna Malovannaya, James F. Martin, David S. Rosenblatt, Ross A. Poché
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
Combined methylmalonic acidemia (MMA) and hyperhomocysteinemias are inborn errors of vitamin B12 metabolism, and mutations in the transcriptional regulators HCFC1 and RONIN (THAP11) underlie some forms of these disorders. Here the authors generated m
Externí odkaz:
https://doaj.org/article/18e20d90d2e9439192ddff6d1fb4cef0
Publikováno v:
TH Open, Vol 04, Iss 01, Pp e33-e35 (2020)
Angiotensin-converting enzyme (ACE) inhibitors are extensively prescribed to treat patients with hypertension, congestive heart failure, and diabetic nephropathy. A small fraction of these patients (approximately 0.7%) develop angioedema, manifested
Externí odkaz:
https://doaj.org/article/3bf1ce01034742d49d515b1aa294be35
Publikováno v:
Cancer Medicine, Vol 6, Iss 4, Pp 809-818 (2017)
Abstract Treatment with dasatinib, a tyrosine kinase inhibitor, is associated with edema, pleural effusion, and pulmonary edema. We investigated the effect of dasatinib on the barrier function of human microvascular endothelial cells‐1 (HMEC‐1) i
Externí odkaz:
https://doaj.org/article/b2f00eaffa584d73a021ad9524497088
Publikováno v:
Psychiatric Quarterly. 93:335-345
Microglial activation has long been posited to be involved in the neurobiology of schizophrenia. However, recent studies indicate that schizophrenia is associated with astrocytic activation, rather than microglia activation. Moreover, elevated levels
Publikováno v:
Transfusion
Background During platelet storage, there are extensive changes in cytoskeleton and phosphatidylserine exposure. The intrinsic mitochondrial pathway of apoptosis, activated in stored platelets, is a major mediator these changes. Cofilin-1 is an effec
Publikováno v:
Blood Coagul Fibrinolysis
OBJECTIVE: Wdr-1, an actin interacting protein, enhances cofilin’s capacity to accelerate depolymerization of F-actin filaments. Wdr-1-deficient mice have impaired hemostasis due to defective inside-out integrin signaling in platelets. Here, we stu
Autor:
Prasenjit Guchhait, Swapan K Dasgupta, Anhquyen Le, Sarvari Yellapragada, José A. López, Perumal Thiagarajan
Publikováno v:
Haematologica, Vol 92, Iss 9 (2007)
Increased exposure of sickle red blood cells to phosphatidylserine promotes its adhesion to the endothelium. A monoclonal antibody to lactadherin, a phosphatidylserine binding protein, inhibits sickle cell adhesion to histamine-stimulated endothelial
Externí odkaz:
https://doaj.org/article/a6f46394ad024afeb06afa95c02f40ce
Autor:
Xuefei Tong, Matthew C. Hill, Jenny J. Sun, Perumal Thiagarajan, Arindam Chaudhury, Lucas C. Reineke, Joel R. Neilson, Russel S. Ray, Ross A. Poché, Tiffany Chern, David Watkins, Martin F. James, Annita Achilleos, Swapan K. Dasgupta
Publikováno v:
The FASEB Journal. 34:1-1
Publikováno v:
Blood. 132:1256-1256
Background Platelets, harvested for transfusion, have a relatively short "shelf life" of 5 days. With increasing storage, platelets develop structural and functional changes called "platelet storage lesions". These changes result not only in reduced
Publikováno v:
Thrombosis Research. 132:217-220
Heparin-induced thrombocytopenia (HIT) is an antibody-mediated syndrome of thrombocytopenia and prothrombotic state that follows exposure to heparin. However, spontaneous HIT has been described in the setting of infection, without evidence of previou