Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Swantje Mohr"'
Publikováno v:
Chemistry (Weinheim an Der Bergstrasse, Germany)
Canonical G‐quadruplexes can adopt a variety of different topologies depending on the arrangement of propeller, lateral, or diagonal loops connecting the four G‐columns. A novel intramolecular G‐quadruplex structure is derived through inversion
Publikováno v:
RSC Chemical Biology
Guanine(G)-rich DNA or RNA sequences can assemble or intramolecularly fold into G-quadruplexes formed through the stacking of planar G·G·G·G tetrads in the presence of monovalent cations. These secondary nucleic acid structures have convincingly b
Publikováno v:
Chemistry (Weinheim an Der Bergstrasse, Germany)
A parallel quadruplex derived from the Myc promoter sequence was extended by a stem‐loop duplex at either its 5′‐ or 3′‐terminus to mimic a quadruplex–duplex (Q–D) junction as a potential genomic target. High‐resolution structures of
Publikováno v:
Angewandte Chemie. 131:11184-11188
Publikováno v:
Angewandte Chemie (International ed. in English). 58(32)
The oligomer d(GCGTG3 TCAG3 TG3 TG3 ACGC) with short complementary flanking sequences at the 5'- and 3'-ends was shown to fold into three different DNA G-quadruplex species. In contrast, a corresponding oligomer that lacks base complementarity betwee