Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Swantje, Held"'
Autor:
Meinolf Karthaus, Volker Heinemann, Jorge Riera-Knorrenschild, Albrecht Kretzschmar, Manfred Welslau, Ulrich Kaiser, Henning Pelz, Thomas J. Ettrich, Swantje Held, Linde Kehmann, Jürgen Hess, Timo Reisländer, Lena Weiss, on behalf of the TALLISUR study group
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background In the pivotal phase III RECOURSE trial, trifluridine/tipiracil (FTD/TPI) improved progression-free and overall survival (PFS, OS) of patients with pre-treated metastatic colorectal cancer (mCRC). Subsequently, the TALLISUR trial
Externí odkaz:
https://doaj.org/article/bfc837e7c22d4f35917763b74a09a350
Autor:
Klara Dorman, Stefan Boeck, Robert J. Snijder, Jens T. Siveke, Michael Schenk, Julia Mayerle, Karel Caca, Jens Freiberg-Richter, Ludwig Fischer von Weikersthal, Frank Kullmann, Anke Reinacher-Schick, Martin Fuchs, Stephan Kanzler, Volker Kunzmann, Thomas J. Ettrich, Danmei Zhang, Swantje Held, Ayad Abdul-Ahad, Michael von Bergwelt-Baildon, Volker Heinemann, Michael Haas
Publikováno v:
Current Oncology, Vol 30, Iss 6, Pp 5828-5834 (2023)
This analysis of the RASH trial (NCT01729481) aimed at gaining a better understanding of the “Burden of Therapy” (BOTh®TM) in pancreatic ductal adenocarcinoma (PDAC). In the RASH study, 150 patients with newly diagnosed metastatic PDAC were trea
Externí odkaz:
https://doaj.org/article/d4ab867951864e49ad0edeb7b333eb01
Autor:
Florian Gebauer, Alexander Ioannis Damanakis, Felix Popp, Alexander Quaas, Fabian Kütting, Katrin Lutz, Swantje Held, Burkhard Deuß, Tobias Göser, Dirk Waldschmidt, Christiane Bruns
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background According to current guidelines, treatment of patients with hepatic oligometastasis in pancreatic cancer is not reflected and systemic chemotherapy is recommended in those patients. Retrospective data suggest beneficial outcomes i
Externí odkaz:
https://doaj.org/article/616c088826884c7d99c7984e35c6d4f5
Autor:
Annika Kurreck, Volker Heinemann, Ludwig Fischer von Weikersthal, Thomas Decker, Florian Kaiser, Jens Uhlig, Michael Schenk, Jens Freiberg-Richter, Bettina Peuser, Claudio Denzlinger, Ullrich Graeven, Kathrin Heinrich, Swantje Held, Arndt Stahler, Annabel Helga Sophie Alig, Ivan Jelas, Jobst C. von Einem, Sebastian Stintzing, Clemens Giessen-Jung, Dominik P. Modest
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
IntroductionEarly tumor shrinkage (ETS), depth of response (DpR), and time to DpR represent exploratory endpoints that may serve as early efficacy parameters and predictors of long-term outcome in metastatic colorectal cancer (mCRC). We analyzed thes
Externí odkaz:
https://doaj.org/article/02c58eab2dbe4e41985915f0822765da
Autor:
Arndt Stahler, Beeke Hoppe, Il-Kang Na, Luisa Keilholz, Lothar Müller, Meinolf Karthaus, Stefan Fruehauf, Ullrich Graeven, Ludwig Fischer von Weikersthal, Eray Goekkurt, Stefan Kasper, Andreas Jay Kind, Annika Kurreck, Annabel Helga Sophie Alig, Swantje Held, Anke Reinacher-Schick, Volker Heinemann, David Horst, Armin Jarosch, Sebastian Stintzing, Tanja Trarbach, Dominik Paul Modest
Publikováno v:
Journal of Clinical Oncology. 41:2975-2987
PURPOSE Consensus molecular subtypes (CMSs) were evaluated as prognostic and predictive biomarkers of patients with RAS wild-type metastatic colorectal cancer (mCRC) receiving fluorouracil and folinic acid (FU/FA) with or without panitumumab (Pmab) a
Autor:
Daniel Heudobler, Christian Schulz, Jürgen R. Fischer, Peter Staib, Thomas Wehler, Thomas Südhoff, Thomas Schichtl, Jochen Wilke, Joachim Hahn, Florian Lüke, Martin Vogelhuber, Sebastian Klobuch, Tobias Pukrop, Wolfgang Herr, Swantje Held, Kristine Beckers, Gauthier Bouche, Albrecht Reichle
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background: Most non-small cell lung cancers occur in elderly and frequently comorbid patients. Therefore, it is necessary to evaluate the efficacy of biomodulatory active therapy regimen, concertedly interfering with tumor-associated homeostatic pat
Externí odkaz:
https://doaj.org/article/120f96cd72e34bd0a075f9e90dccdae2
Autor:
Martin Metzenmacher, Hans-Georg Kopp, Frank Griesinger, Niels Reinmuth, Martin Sebastian, Monika Serke, Cornelius Florian Waller, Michael Thomas, Jochen Eggert, Gerald Schmid-Bindert, Mathias Hoiczyk, Daniel Christian Christoph, Martin Kimmich, Burkhard Deuß, Stephanie Seifert, Swantje Held, Martin Schuler, Thomas Herold, Frank Breitenbuecher, Wilfried Ernst Erich Eberhardt
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 13 (2021)
Background: Pemetrexed and cisplatin is a first-line standard in non-squamous non-small-cell lung cancer without targetable mutations. It became the backbone of checkpoint-inhibitor–chemotherapy combinations. Single high doses of cisplatin pose tox
Externí odkaz:
https://doaj.org/article/d242cd41cb214934942f7de020430e08
Autor:
Volker Heinemann, Andreas Jung, Thomas Kirchner, Jens Neumann, Markus Moehler, Thomas Decker, Swantje Held, Alexander Kiani, Martina Stauch, Andreas Schalhorn, Nicolas Moosmann, Ludwig Fischer von Weikersthal, Florian Kaiser, Boryana Ivanova, Christine Kapaun, Clemens Giessen-Jung, Ingrid Ricard, Dominik P. Modest, Sebastian Stintzing, Arndt Stahler
Outcome according to high vs. low unnormalized AREG expression in all patients and subgroups
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41829af0bb1ad893d90f8cb3597f0079
https://doi.org/10.1158/1078-0432.22476932
https://doi.org/10.1158/1078-0432.22476932
Autor:
Volker Heinemann, Andreas Jung, Thomas Kirchner, Jens Neumann, Markus Moehler, Thomas Decker, Swantje Held, Alexander Kiani, Martina Stauch, Andreas Schalhorn, Nicolas Moosmann, Ludwig Fischer von Weikersthal, Florian Kaiser, Boryana Ivanova, Christine Kapaun, Clemens Giessen-Jung, Ingrid Ricard, Dominik P. Modest, Sebastian Stintzing, Arndt Stahler
Purpose:Amphiregulin (AREG) and epiregulin (EREG) are ligands of EGFR. Predictive information for anti-EGFR treatment in metastatic colorectal cancer (mCRC) was observed, but data for other agents is limited.Experimental Design:Ligand mRNA expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52050a7f74cba65dfcd8f207d1d8d346
https://doi.org/10.1158/1078-0432.c.6529532.v1
https://doi.org/10.1158/1078-0432.c.6529532.v1
Autor:
Volker Heinemann, Andreas Jung, Thomas Kirchner, Jens Neumann, Markus Moehler, Thomas Decker, Swantje Held, Alexander Kiani, Martina Stauch, Andreas Schalhorn, Nicolas Moosmann, Ludwig Fischer von Weikersthal, Florian Kaiser, Boryana Ivanova, Christine Kapaun, Clemens Giessen-Jung, Ingrid Ricard, Dominik P. Modest, Sebastian Stintzing, Arndt Stahler
Univariate and multivariate Cox regression analyses for overall and progression-free survival in all patients.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29eeaf1c1ffd6093702b6991bb323397
https://doi.org/10.1158/1078-0432.22476935.v1
https://doi.org/10.1158/1078-0432.22476935.v1