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Parameterizing mechanistic niche models in biophysical ecology: a review of empirical approaches.

Autor: Riddell EA; Department of Ecology, Evolution, and Organismal Biology, Iowa State University, Ames, IA 50011, USA.; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Burger IJ; Department of Ecology, Evolution, and Organismal Biology, Iowa State University, Ames, IA 50011, USA.; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Tyner-Swanson TL; Department of Ecology, Evolution, and Organismal Biology, Iowa State University, Ames, IA 50011, USA., Biggerstaff J; Department of Ecology, Evolution, and Organismal Biology, Iowa State University, Ames, IA 50011, USA., Muñoz MM; Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT 06511, USA., Levy O; Faculty of Life Sciences, School of Zoology, Tel Aviv University, Tel Aviv 6997801, Israel., Porter CK; Department of Ecology, Evolution, and Organismal Biology, Iowa State University, Ames, IA 50011, USA.

Publikováno v: The Journal of experimental biology [J Exp Biol] 2023 Nov 15; Vol. 226 (22). Date of Electronic Publication: 2023 Nov 13.

Enantiomeric Separation, Absolute Configuration by X-ray Crystallographic Analysis, and Functional Evaluation of Enantiomers of the Dual Ligand, SYA0340 at 5-HT 1A and 5-HT 7A Receptors.

Autor: Bricker BA; Division of Basic Pharmaceutical Sciences, College of Pharmacy and Pharmaceutical Sciences, Institute of Public Health, Florida A&M University, Tallahassee, Florida 32307, United States., Voshavar C; Division of Basic Pharmaceutical Sciences, College of Pharmacy and Pharmaceutical Sciences, Institute of Public Health, Florida A&M University, Tallahassee, Florida 32307, United States., Onyameh EK; Division of Basic Pharmaceutical Sciences, College of Pharmacy and Pharmaceutical Sciences, Institute of Public Health, Florida A&M University, Tallahassee, Florida 32307, United States., Gonela UM; Division of Basic Pharmaceutical Sciences, College of Pharmacy and Pharmaceutical Sciences, Institute of Public Health, Florida A&M University, Tallahassee, Florida 32307, United States., Lin X; Department of Chemistry and Biochemistry, Florida State University, 95 Chieftan Way Room 118 DLC, Tallahassee, Florida 32306-4390, United States., Swanson TL; Research Service, VA Portland Health Care System, and Department of Psychiatry, Oregon Health and Science University, Portland Oregon 97239, United States., Kozell LB; Research Service, VA Portland Health Care System, and Department of Psychiatry, Oregon Health and Science University, Portland Oregon 97239, United States., Schmachtenberg JL; Research Service, VA Portland Health Care System, and Department of Psychiatry, Oregon Health and Science University, Portland Oregon 97239, United States., Bloom SH; Research Service, VA Portland Health Care System, and Department of Psychiatry, Oregon Health and Science University, Portland Oregon 97239, United States., Janowsky AJ; Research Service, VA Portland Health Care System, and Department of Psychiatry, Oregon Health and Science University, Portland Oregon 97239, United States., Ablordeppey SY; Division of Basic Pharmaceutical Sciences, College of Pharmacy and Pharmaceutical Sciences, Institute of Public Health, Florida A&M University, Tallahassee, Florida 32307, United States.

Publikováno v: ACS omega [ACS Omega] 2023 Jun 07; Vol. 8 (24), pp. 21736-21744. Date of Electronic Publication: 2023 Jun 07 (Print Publication: 2023).

A highly D 3 R-selective and efficacious partial agonist (S)-ABS01-113 compared to its D 3 R-selective antagonist enantiomer (R)-ABS01-113 as potential treatments for opioid use disorder.

Autor: Galaj E; Medicinal Chemistry Section, Molecular Targets and Medication Discovery Branch, National Institute on Drug Abuse-Intramural Research Program, Baltimore, MD, USA.; Department of Psychological and Brain Sciences, Colgate University, Hamilton, NY, USA., Bi GH; Medicinal Chemistry Section, Molecular Targets and Medication Discovery Branch, National Institute on Drug Abuse-Intramural Research Program, Baltimore, MD, USA., Klein B; Medicinal Chemistry Section, Molecular Targets and Medication Discovery Branch, National Institute on Drug Abuse-Intramural Research Program, Baltimore, MD, USA., Hempel B; Medicinal Chemistry Section, Molecular Targets and Medication Discovery Branch, National Institute on Drug Abuse-Intramural Research Program, Baltimore, MD, USA., Shaik AB; Medicinal Chemistry Section, Molecular Targets and Medication Discovery Branch, National Institute on Drug Abuse-Intramural Research Program, Baltimore, MD, USA., Gogarnoiu ES; Medicinal Chemistry Section, Molecular Targets and Medication Discovery Branch, National Institute on Drug Abuse-Intramural Research Program, Baltimore, MD, USA., Friedman J; Medicinal Chemistry Section, Molecular Targets and Medication Discovery Branch, National Institute on Drug Abuse-Intramural Research Program, Baltimore, MD, USA.; Johns Hopkins Drug Discovery, Johns Hopkins School of Medicine, Baltimore, MD, 21205, USA., Lam J; Medicinal Chemistry Section, Molecular Targets and Medication Discovery Branch, National Institute on Drug Abuse-Intramural Research Program, Baltimore, MD, USA.; Johns Hopkins Drug Discovery, Johns Hopkins School of Medicine, Baltimore, MD, 21205, USA., Rais R; Johns Hopkins Drug Discovery, Johns Hopkins School of Medicine, Baltimore, MD, 21205, USA.; Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD, 21205, USA., Reed JF; Research Service, VA Portland Health Care System, Portland, OR, USA., Bloom SH; Research Service, VA Portland Health Care System, Portland, OR, USA., Swanson TL; Research Service, VA Portland Health Care System, Portland, OR, USA., Schmachtenberg JL; Research Service, VA Portland Health Care System, Portland, OR, USA., Eshleman AJ; Research Service, VA Portland Health Care System, and Departments of Psychiatry and Behavioral Neuroscience, Oregon Health and Science University, Portland, OR, USA., Janowsky A; Research Service, VA Portland Health Care System, and Departments of Psychiatry and Behavioral Neuroscience, Oregon Health and Science University, Portland, OR, USA., Xi ZX; Medicinal Chemistry Section, Molecular Targets and Medication Discovery Branch, National Institute on Drug Abuse-Intramural Research Program, Baltimore, MD, USA., Newman AH; Medicinal Chemistry Section, Molecular Targets and Medication Discovery Branch, National Institute on Drug Abuse-Intramural Research Program, Baltimore, MD, USA. anewman@intra.nida.nih.gov.

Publikováno v: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology [Neuropsychopharmacology] 2022 Dec; Vol. 47 (13), pp. 2309-2318. Date of Electronic Publication: 2022 Jul 25.

Fentanyl but not Morphine Interacts with Nonopioid Recombinant Human Neurotransmitter Receptors and Transporters.

Autor: Torralva R; Research Service, VA Portland Health Care System, Portland, Oregon (R.T., A.J.E., T.L.S., J.L.S., W.E.S., S.H.B., K.M.W., J.F.R., A.J.); Coda Research, Portland, Oregon (R.T.); Departments of Psychiatry (R.T., A.J.E., T.L.S., J.L.S., W.E.S., S.H.B., K.M.W., J.F.R., A.J.), Behavioral Neuroscience (A.J.E., A.J.), Oregon Health & Science University, Portland, Oregon; and The Methamphetamine Abuse Research Center, VA Portland Health Care System and Oregon Health & Science University, Portland, Oregon (W.E.S., A.J.)., Eshleman AJ; Research Service, VA Portland Health Care System, Portland, Oregon (R.T., A.J.E., T.L.S., J.L.S., W.E.S., S.H.B., K.M.W., J.F.R., A.J.); Coda Research, Portland, Oregon (R.T.); Departments of Psychiatry (R.T., A.J.E., T.L.S., J.L.S., W.E.S., S.H.B., K.M.W., J.F.R., A.J.), Behavioral Neuroscience (A.J.E., A.J.), Oregon Health & Science University, Portland, Oregon; and The Methamphetamine Abuse Research Center, VA Portland Health Care System and Oregon Health & Science University, Portland, Oregon (W.E.S., A.J.)., Swanson TL; Research Service, VA Portland Health Care System, Portland, Oregon (R.T., A.J.E., T.L.S., J.L.S., W.E.S., S.H.B., K.M.W., J.F.R., A.J.); Coda Research, Portland, Oregon (R.T.); Departments of Psychiatry (R.T., A.J.E., T.L.S., J.L.S., W.E.S., S.H.B., K.M.W., J.F.R., A.J.), Behavioral Neuroscience (A.J.E., A.J.), Oregon Health & Science University, Portland, Oregon; and The Methamphetamine Abuse Research Center, VA Portland Health Care System and Oregon Health & Science University, Portland, Oregon (W.E.S., A.J.)., Schmachtenberg JL; Research Service, VA Portland Health Care System, Portland, Oregon (R.T., A.J.E., T.L.S., J.L.S., W.E.S., S.H.B., K.M.W., J.F.R., A.J.); Coda Research, Portland, Oregon (R.T.); Departments of Psychiatry (R.T., A.J.E., T.L.S., J.L.S., W.E.S., S.H.B., K.M.W., J.F.R., A.J.), Behavioral Neuroscience (A.J.E., A.J.), Oregon Health & Science University, Portland, Oregon; and The Methamphetamine Abuse Research Center, VA Portland Health Care System and Oregon Health & Science University, Portland, Oregon (W.E.S., A.J.)., Schutzer WE; Research Service, VA Portland Health Care System, Portland, Oregon (R.T., A.J.E., T.L.S., J.L.S., W.E.S., S.H.B., K.M.W., J.F.R., A.J.); Coda Research, Portland, Oregon (R.T.); Departments of Psychiatry (R.T., A.J.E., T.L.S., J.L.S., W.E.S., S.H.B., K.M.W., J.F.R., A.J.), Behavioral Neuroscience (A.J.E., A.J.), Oregon Health & Science University, Portland, Oregon; and The Methamphetamine Abuse Research Center, VA Portland Health Care System and Oregon Health & Science University, Portland, Oregon (W.E.S., A.J.)., Bloom SH; Research Service, VA Portland Health Care System, Portland, Oregon (R.T., A.J.E., T.L.S., J.L.S., W.E.S., S.H.B., K.M.W., J.F.R., A.J.); Coda Research, Portland, Oregon (R.T.); Departments of Psychiatry (R.T., A.J.E., T.L.S., J.L.S., W.E.S., S.H.B., K.M.W., J.F.R., A.J.), Behavioral Neuroscience (A.J.E., A.J.), Oregon Health & Science University, Portland, Oregon; and The Methamphetamine Abuse Research Center, VA Portland Health Care System and Oregon Health & Science University, Portland, Oregon (W.E.S., A.J.)., Wolfrum KM; Research Service, VA Portland Health Care System, Portland, Oregon (R.T., A.J.E., T.L.S., J.L.S., W.E.S., S.H.B., K.M.W., J.F.R., A.J.); Coda Research, Portland, Oregon (R.T.); Departments of Psychiatry (R.T., A.J.E., T.L.S., J.L.S., W.E.S., S.H.B., K.M.W., J.F.R., A.J.), Behavioral Neuroscience (A.J.E., A.J.), Oregon Health & Science University, Portland, Oregon; and The Methamphetamine Abuse Research Center, VA Portland Health Care System and Oregon Health & Science University, Portland, Oregon (W.E.S., A.J.)., Reed JF; Research Service, VA Portland Health Care System, Portland, Oregon (R.T., A.J.E., T.L.S., J.L.S., W.E.S., S.H.B., K.M.W., J.F.R., A.J.); Coda Research, Portland, Oregon (R.T.); Departments of Psychiatry (R.T., A.J.E., T.L.S., J.L.S., W.E.S., S.H.B., K.M.W., J.F.R., A.J.), Behavioral Neuroscience (A.J.E., A.J.), Oregon Health & Science University, Portland, Oregon; and The Methamphetamine Abuse Research Center, VA Portland Health Care System and Oregon Health & Science University, Portland, Oregon (W.E.S., A.J.)., Janowsky A; Research Service, VA Portland Health Care System, Portland, Oregon (R.T., A.J.E., T.L.S., J.L.S., W.E.S., S.H.B., K.M.W., J.F.R., A.J.); Coda Research, Portland, Oregon (R.T.); Departments of Psychiatry (R.T., A.J.E., T.L.S., J.L.S., W.E.S., S.H.B., K.M.W., J.F.R., A.J.), Behavioral Neuroscience (A.J.E., A.J.), Oregon Health & Science University, Portland, Oregon; and The Methamphetamine Abuse Research Center, VA Portland Health Care System and Oregon Health & Science University, Portland, Oregon (W.E.S., A.J.) janowsky@ohsu.edu.

Publikováno v: The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2020 Sep; Vol. 374 (3), pp. 376-391. Date of Electronic Publication: 2020 Jun 08.