Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Swamy Rakesh Adapa"'
The DEAD-box RNA helicase PfDOZI imposes opposing actions on RNA metabolism in Plasmodium falciparum
Autor:
Hui Min, Xiaoying Liang, Chengqi Wang, Junling Qin, Rachasak Boonhok, Azhar Muneer, Awtum M. Brashear, Xiaolian Li, Allen M. Minns, Swamy Rakesh Adapa, Rays H. Y. Jiang, Gang Ning, Yaming Cao, Scott E. Lindner, Jun Miao, Liwang Cui
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract In malaria parasites, the regulation of mRNA translation, storage and degradation during development and life-stage transitions remains largely unknown. Here, we functionally characterized the DEAD-box RNA helicase PfDOZI in P. falciparum. D
Externí odkaz:
https://doaj.org/article/65f9cfb51bd8495780fbf994ff77ce7e
Autor:
Amuza Byaruhanga Lucky, Chengqi Wang, Min Liu, Xiaoying Liang, Hui Min, Qi Fan, Faiza Amber Siddiqui, Swamy Rakesh Adapa, Xiaolian Li, Rays H. Y. Jiang, Xiaoguang Chen, Liwang Cui, Jun Miao
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-18 (2023)
Abstract Protein arginine methyltransferases (PRMTs) regulate many important cellular processes, such as transcription and RNA processing in model organisms but their functions in human malaria parasites are not elucidated. Here, we characterize PfPR
Externí odkaz:
https://doaj.org/article/24e94d5bac0b46369b31a3d982058e7b
Autor:
Camilla Valente Pires, Jenna Oberstaller, Chengqi Wang, Debora Casandra, Min Zhang, Jyotsna Chawla, Swamy Rakesh Adapa, Thomas D. Otto, Michael T. Ferdig, Julian C. Rayner, Rays H. Y. Jiang, John H. Adams
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT The antimalarial activity of the frontline drug artemisinin involves generation of reactive oxygen species (ROS) leading to oxidative damage of parasite proteins. To achieve homeostasis and maintain protein quality control in the overwhelmed
Externí odkaz:
https://doaj.org/article/9413a8d85df74786a63a64dc93cec61b
Autor:
Jun Miao, Chengqi Wang, Amuza Byaruhanga Lucky, Xiaoying Liang, Hui Min, Swamy Rakesh Adapa, Rays Jiang, Kami Kim, Liwang Cui
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8, p e1009351 (2021)
The histone acetyltransferase GCN5-associated SAGA complex is evolutionarily conserved from yeast to human and functions as a general transcription co-activator in global gene regulation. In this study, we identified a divergent GCN5 complex in Plasm
Externí odkaz:
https://doaj.org/article/dc8419512ba847dca8627faefb1909bd
Autor:
Alison Roth, Steven P. Maher, Amy J. Conway, Ratawan Ubalee, Victor Chaumeau, Chiara Andolina, Stephen A. Kaba, Amélie Vantaux, Malina A. Bakowski, Richard Thomson-Luque, Swamy Rakesh Adapa, Naresh Singh, Samantha J. Barnes, Caitlin A. Cooper, Mélanie Rouillier, Case W. McNamara, Sebastian A. Mikolajczak, Noah Sather, Benoît Witkowski, Brice Campo, Stefan H. I. Kappe, David E. Lanar, François Nosten, Silas Davidson, Rays H. Y. Jiang, Dennis E. Kyle, John H. Adams
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Currently available platforms to study liver stage of Plasmodium species have limitations. Here, the authors show that primary human hepatocyte cultures in 384-well format support hypnozoite and other liver stage development and are suitable for drug
Externí odkaz:
https://doaj.org/article/0b14f6d533014ef091394f171d42ba23
Autor:
Gloria C. Ferreira, Jenna Oberstaller, Renée Fonseca, Thomas E. Keller, Swamy Rakesh Adapa, Justin Gibbons, Chengqi Wang, Xiaoming Liu, Chang Li, Minh Pham, Guy W. Dayhoff II, Linh M. Duong, Luis Tañón Reyes, Luciano Enrique Laratelli, Douglas Franz, Segun Fatumo, ATM Golam Bari, Audrey Freischel, Lindsey Fiedler, Omkar Dokur, Krishna Sharma, Deborah Cragun, Ben Busby, Rays H.Y. Jiang
Publikováno v:
F1000Research, Vol 8 (2019)
Background: Basic and clinical scientific research at the University of South Florida (USF) have intersected to support a multi-faceted approach around a common focus on rare iron-related diseases. We proposed a modified version of the National Cente
Externí odkaz:
https://doaj.org/article/4a7ad9b62dfe44e2ad3ff1c09b932936
Autor:
Alison Roth, Steven P. Maher, Amy J. Conway, Ratawan Ubalee, Victor Chaumeau, Chiara Andolina, Stephen A. Kaba, Amélie Vantaux, Malina A. Bakowski, Richard Thomson-Luque, Swamy Rakesh Adapa, Naresh Singh, Samantha J. Barnes, Caitlin A. Cooper, Mélanie Rouillier, Case W. McNamara, Sebastian A. Mikolajczak, Noah Sather, Benoît Witkowski, Brice Campo, Stefan H. I. Kappe, David E. Lanar, François Nosten, Silas Davidson, Rays H. Y. Jiang, Dennis E. Kyle, John H. Adams
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
The original version of this Article contained an error in the spelling of Richard Thomson-Luque, which was incorrectly given as Richard Thomson Luque. This error has now been corrected in both the PDF and HTML versions of the Article.
Externí odkaz:
https://doaj.org/article/73adfbdede8e4de38681a2951dacd5ea
Autor:
Jenna Oberstaller, Swamy Rakesh Adapa, Guy W. Dayhoff II, Justin Gibbons, Thomas E. Keller, Chang Li, Jean Lim, Minh Pham, Anujit Sarkar, Ravi Sharma, Agaz H. Wani, Andrea Vianello, Linh M. Duong, Chenggi Wang, Celine Grace F. Atkinson, Madeleine Barrow, Nathan W. Van Bibber, Jan Dahrendorff, David A. E. Dean, Omkar Dokur, Gloria C. Ferreira, Mitchell Hastings, Gregory S. Herbert, Khandaker Tasnim Huq, Youngchul Kim, Xiangyun Liao, XiaoMing Liu, Fahad Mansuri, Lynn B. Martin, Elizabeth M. Miller, Ojas Natarajan, Jinyong Pang, Francesca Prieto, Peter W. Radulovic, Vyoma Sheth, Matthew Sumpter, Desirae Sutherland, Nisha Vijayakumar, Rays H. Y. Jiang
Publikováno v:
F1000Research. 9:1478
Microbiome data are undergoing exponential growth powered by rapid technological advancement. As the scope and depth of microbiome research increases, cross-disciplinary research is urgently needed for interpreting and harnessing the unprecedented da
Autor:
Richard, Thomson-Luque, Chengqi, Wang, Francis B, Ntumngia, Shulin, Xu, Karoly, Szekeres, Amy, Conway, Swamy Rakesh, Adapa, Samantha J, Barnes, John H, Adams, Rays H Y, Jiang
Publikováno v:
Blood Cells, Molecules & Diseases
Progress towards an in-depth understanding of the final steps of the erythroid lineage development is paramount for many hematological diseases. We have characterized the final stages of reticulocyte maturation from bone marrow to peripheral blood us
Autor:
Swamy Rakesh Adapa
Publikováno v:
Scopus-Elsevier
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::34e49c401d63a45cdbe4910442fa290f
http://www.scopus.com/inward/record.url?eid=2-s2.0-77950497932&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-77950497932&partnerID=MN8TOARS