Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Swaminathan, Venkatesh"'
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Maintenance of chromatin structure in coding regions is partially dependent on transcription, with histone methyltransferase Set2 playing a role in this process. Here, the authors provide evidence that Set2 regulates repression of a specific set of a
Externí odkaz:
https://doaj.org/article/1ef059dc47f940508d6d5a9b3cc1e47b
Autor:
Janardhanam, Srihari B., Prakasam, Sivaraman, Swaminathan, Venkatesh T., Kodumudi, Krithika N., Zunt, Susan L., Srinivasan, Mythily ⁎
Publikováno v:
In Archives of Oral Biology May 2012 57(5):495-502
Autor:
Govind, Chhabi K. 1, 2, ∗, Qiu, Hongfang 1, Ginsburg, Daniel S. 1, Ruan, Chun 3, Hofmeyer, Kimberly 1, Hu, Cuihua 1, Swaminathan, Venkatesh 4, Workman, Jerry L. 4, Li, Bing 3, Hinnebusch, Alan G. 1, ∗∗
Publikováno v:
In Molecular Cell 30 July 2010 39(2):234-246
Autor:
Balasubramanyam, Karanam ‡, §, ¶, Varier, Radhika A. ‡, §, Altaf, Mohammed ‡, §, Swaminathan, Venkatesh ‡, ∥, Siddappa, Nagadenahalli B. ∥, **, Ranga, Udaykumar **, ‡‡, Kundu, Tapas K. ‡, §§
Publikováno v:
In Journal of Biological Chemistry 3 December 2004 279(49):51163-51171
Autor:
Swaminathan Venkatesh, Madelaine Gogol, Jerry L. Workman, Jeong Hoon Kim, Laurence Florens, Michael P. Washburn, Joshua M. Gilmore, Michaela Smolle, Arnob Dutta
Publikováno v:
Genes & Development. 28:2314-2330
The Swi/Snf chromatin remodeling complex functions to alter nucleosome positions by either sliding nucleosomes on DNA or the eviction of histones. The presence of histone acetylation and activator-dependent recruitment and retention of Swi/Snf is imp
Autor:
Jennifer L. Gerton, Jerry L. Workman, Mark Mattingly, Swaminathan Venkatesh, Laurence Florens, Geetha S. Hewawasam, Ying Zhang
Publikováno v:
The Journal of Biological Chemistry
Background: Psh1 is an E3 ubiquitin ligase that controls CenH3/Cse4 levels through proteolysis in budding yeast. Results: Psh1 is phosphorylated in vivo by CK2, and its E3 ligase activity is promoted. Conclusion: Phosphorylation is crucial in Psh1-as
Publikováno v:
Wiley Interdisciplinary Reviews: Developmental Biology. 2:685-700
Set2 is a RNA Polymerase II (RNAPII) associated histone methyltransferase involved in the co-transcriptional methylation of the H3 K36 residue (H3K36me). It is responsible for multiple degrees of methylation (mono-, di-, tri-), each of which has a di
Publikováno v:
Epigenetics. 8:10-15
Maintenance of ordered chromatin structure over the body of genes is vital for the regulation of transcription. Increased access to the underlying DNA sequence results in the recruitment of RNA polymerase II to inappropriate, promoter-like sites with
Publikováno v:
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Maintenance of a regular chromatin structure over the coding regions of genes occurs co-transcriptionally via the ‘chromatin resetting' pathway. One of the central players in this pathway is the histone methyltransferase Set2. Here we show that the
Autor:
Laurence Florens, Ying Zhang, Michael P. Washburn, Hua Li, Michaela Smolle, Jerry L. Workman, Swaminathan Venkatesh, Madelaine Gogol
Publikováno v:
Nature structural & molecular biology
Set2-mediated methylation of histone H3 Lys36 (H3K36) is a mark associated with the coding sequences of actively transcribed genes, yet plays a negative role during transcription elongation. It prevents trans-histone exchange over coding regions and