Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Swaine, David J."'
Autor:
Kirwan, Ian G., Loadman, Paul, Swaine, David J., Anthoney, Alan, Pettit, G.R., Lippert III, J.W., Shnyder, Steven, Cooper, Patricia A., Bibby, Michael C.
Purpose: Combretastatin A4 phosphate (CA4P) and its structural analog, combretastatin A1 phosphate (CA1P), are soluble prodrugs capable of interacting with tubulin and causing rapid vascular shutdown within tumors. CA4P has completed Phase I clinical
Externí odkaz:
http://hdl.handle.net/10454/13684
Purpose: The hollow fiber assay is used successfully as a routine in vivo screening model to quantitatively define anticancer activity by the National Cancer Institute. This study investigates whether the hollow fiber assay can be used as a short-ter
Externí odkaz:
http://hdl.handle.net/10454/3938
Phortress is a novel, potent, and selective experimental antitumor agent. Its mechanism of action involves induction of CYP1A1-catalyzed biotransformation of 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole (5F 203) to generate electrophilic species,
Externí odkaz:
http://hdl.handle.net/10454/3159
Autor:
Loadman, Paul M., Bibby, Michael C., Shnyder, Steven D., Swaine, David J., Kirwan, Ian G., Anthoney, Alan, Cooper, Patricia A., Lippert, J.W.
Purpose: Combretastatin A4 phosphate (CA4P) and its structural analog, combretastatin A1 phosphate (CA1P), are soluble prodrugs capable of interacting with tubulin and causing rapid vascular shutdown within tumors. CA4P has completed Phase I clinical
Externí odkaz:
http://hdl.handle.net/10454/2953
Autor:
Pavillard, Valérie, Drbal, Abedalnaser A.A., Swaine, David J., Phillips, Roger M., Double, John A., Nicolaou, Anna
Publikováno v:
In Biochemical Pharmacology 2004 67(8):1587-1599
Akademický článek
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Autor:
Leong CO; Centre for Biomolecular Sciences, School of Pharmacy, University of Nottingham, Nottingham, United Kingdom., Suggitt M, Swaine DJ, Bibby MC, Stevens MF, Bradshaw TD
Publikováno v:
Molecular cancer therapeutics [Mol Cancer Ther] 2004 Dec; Vol. 3 (12), pp. 1565-75.
Autor:
Suggitt M; Tom Connors Cancer Research Centre, University of Bradford, Bradford, United Kingdom., Swaine DJ, Pettit GR, Bibby MC
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2004 Oct 01; Vol. 10 (19), pp. 6677-85.
Autor:
Kirwan IG; Cancer Research Unit, Tom Connors Cancer Research Centre, University of Bradford, Bradford, United Kingdom., Loadman PM, Swaine DJ, Anthoney DA, Pettit GR, Lippert JW 3rd, Shnyder SD, Cooper PA, Bibby MC
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2004 Feb 15; Vol. 10 (4), pp. 1446-53.