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Autor:
Swain, Peter S
These notes provide a short, focused introduction to modelling stochastic gene expression, including a derivation of the master equation, the recovery of deterministic dynamics, birth-and-death processes, and Langevin theory. The notes were last upda
Externí odkaz:
http://arxiv.org/abs/1607.07806
Autor:
Shahrezaei, Vahid, Swain, Peter S.
Publikováno v:
Proc Natl Acad Sci U S A. 2008 Nov 11;105(45):17256-61
Gene expression is significantly stochastic making modeling of genetic networks challenging. We present an approximation that allows the calculation of not only the mean and variance but also the distribution of protein numbers. We assume that protei
Externí odkaz:
http://arxiv.org/abs/0812.3344
Publikováno v:
Molecular Systems Biology 4:196 (2008)
Stochasticity is both exploited and controlled by cells. Although the intrinsic stochasticity inherent in biochemistry is relatively well understood, cellular variation, or 'noise', is predominantly generated by interactions of the system of interest
Externí odkaz:
http://arxiv.org/abs/0809.2973
Autor:
Granados, Alejandro A., Pietsch, Julian M. J., Cepeda-Humerez, Sarah A., Farquhar, Iseabail L., Tkačik, Gǎsper, Swain, Peter S.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2018 Jun 01. 115(23), 6088-6093.
Externí odkaz:
https://www.jstor.org/stable/26510327
Publikováno v:
Science, 2005 Mar . 307(5717), 1962-1965.
Externí odkaz:
https://www.jstor.org/stable/3841889
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2002 Oct 01. 99(20), 12795-12800.
Externí odkaz:
https://www.jstor.org/stable/3073302
Publikováno v:
Science, 2002 Aug . 297(5584), 1183-1186.
Externí odkaz:
https://www.jstor.org/stable/3832225
Autor:
Pietsch, Julian M. J., Muñoz, Alán F., Adjavon, Diane-Yayra A., Farquhar, Iseabail, Clark, Ivan B. N., Swain, Peter S.
Publikováno v:
eLife; 7/26/2023, p1-48, 48p
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2015 Mar 01. 112(9), E1038-E1047.
Externí odkaz:
https://www.jstor.org/stable/26461729