Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Swafvan Kaipakasseri"'
Autor:
Hoon Kim, Ashique Palakkathondi, Bijo Mathew, Swafvan Kaipakasseri, Sang Ryong Lee, Fathima Sahla Kavully, Sanal Dev, Gaber El-Saber Batiha, Najat Marraiki, Nicola Gambacorta, Geum Seok Jeong, Orazio Nicolotti
Publikováno v:
ChemMedChem. 15:2257-2263
Chalcones are considered effective templates for the development of monoamine oxidase (MAO) and cholinesterase (ChE) inhibitors. The present work describes the syntheses of selected 1,3-benzodioxine-containing chalcones (CD3, CD8 and CD10), and their
Autor:
Rinshana Fathima Abdul Azeez, Ajeesh Vengamthodi, Bijo Mathew, Fathima Sahla Kavully, Anna Rita Tondo, Sanal Dev, Swafvan Kaipakasseri, Hoon Kim, Ashique Palakkathondi, Jong Min Oh, Orazio Nicolotti
Publikováno v:
Journal of Pharmacy and Pharmacology. 72:916-926
ObjectivesTo develop of new class of selective and reversible MAO-B inhibitors from enamides.MethodsSyntheses of the titled derivatives (AD1–AD11) were achieved by reacting cinnamoyl chloride and various primary and secondary amines in basic medium
Autor:
Hoon Kim, Ashique Palakkathondi, Bijo Mathew, Jong Min Oh, Nicola Gambacorta, Swafvan Kaipakasseri, Fathima Sahla Kavully, Orazio Nicolotti, Sanal Dev, T. M. Rangarajan
Publikováno v:
ACS combinatorial science. 22(11)
Fourteen (hetero-)(arylidene)arylhydrazide derivatives (ABH1-ABH14) were synthesized, and their inhibitory activities against monoamine oxidases (MAOs) and acetylcholinesterase (AChE) were evaluated. Compound ABH5 most potently inhibited MAO-B with a