CDK1-mediated BCL9 phosphorylation inhibits clathrin to promote mitotic Wnt signalling.

Autor: Chen J; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicine of Zhejiang Province, Engineering Laboratory of Development and Application of Traditional Chinese Medicine from Zhejiang Province, School of Medicine, Holistic Integrative Pharmacy Institutes (HIPI), Hangzhou Normal University, Hangzhou, China ncmcjx@yeah.net cmrhkm@nccs.com.sg.; Laboratory of Cancer Genomics, Division of Cellular and Molecular Research, National Cancer Centre Singapore, Singapore City, Singapore.; Institute of Molecular and Cell Biology, A*STAR, Proteos, Singapore., Rajasekaran M; Laboratory of Cancer Genomics, Division of Cellular and Molecular Research, National Cancer Centre Singapore, Singapore City, Singapore., Xia H; Laboratory of Cancer Genomics, Division of Cellular and Molecular Research, National Cancer Centre Singapore, Singapore City, Singapore., Kong SN; Laboratory of Cancer Genomics, Division of Cellular and Molecular Research, National Cancer Centre Singapore, Singapore City, Singapore., Deivasigamani A; Laboratory of Cancer Genomics, Division of Cellular and Molecular Research, National Cancer Centre Singapore, Singapore City, Singapore., Sekar K; Laboratory of Cancer Genomics, Division of Cellular and Molecular Research, National Cancer Centre Singapore, Singapore City, Singapore., Gao H; Laboratory of Cancer Genomics, Division of Cellular and Molecular Research, National Cancer Centre Singapore, Singapore City, Singapore., Swa HL; Institute of Molecular and Cell Biology, A*STAR, Proteos, Singapore., Gunaratne J; Institute of Molecular and Cell Biology, A*STAR, Proteos, Singapore., Ooi LL; Division of Surgery, Singapore General Hospital, Singapore City, Singapore., Xie T; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicine of Zhejiang Province, Engineering Laboratory of Development and Application of Traditional Chinese Medicine from Zhejiang Province, School of Medicine, Holistic Integrative Pharmacy Institutes (HIPI), Hangzhou Normal University, Hangzhou, China., Hong W; Institute of Molecular and Cell Biology, A*STAR, Proteos, Singapore., Hui KM; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicine of Zhejiang Province, Engineering Laboratory of Development and Application of Traditional Chinese Medicine from Zhejiang Province, School of Medicine, Holistic Integrative Pharmacy Institutes (HIPI), Hangzhou Normal University, Hangzhou, China ncmcjx@yeah.net cmrhkm@nccs.com.sg.; Laboratory of Cancer Genomics, Division of Cellular and Molecular Research, National Cancer Centre Singapore, Singapore City, Singapore.; Institute of Molecular and Cell Biology, A*STAR, Proteos, Singapore.; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore City, Singapore.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore City, Singapore.

Publikováno v: The EMBO journal [EMBO J] 2018 Oct 15; Vol. 37 (20). Date of Electronic Publication: 2018 Sep 14.

EBprot: Statistical analysis of labeling-based quantitative proteomics data.

Autor: Koh HW; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore., Swa HL; Institute of Molecular and Cell Biology, A*STAR, Singapore., Fermin D; Department of Pathology, Yale University, New Haven, CT, USA., Ler SG; Institute of Molecular and Cell Biology, A*STAR, Singapore., Gunaratne J; Institute of Molecular and Cell Biology, A*STAR, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Choi H; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.; Institute of Molecular and Cell Biology, A*STAR, Singapore.

Publikováno v: Proteomics [Proteomics] 2015 Aug; Vol. 15 (15), pp. 2580-91. Date of Electronic Publication: 2015 May 28.

Altered protein expression profile associated with phenotypic changes in lung fibroblasts co-cultured with gold nanoparticle-treated small airway epithelial cells.

Autor: Ng CT; Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, 4 Medical Drive, Block MD10, S117594, Singapore., Yung LY; Department of Chemical and Biomolecular Engineering, National University of Singapore, 4 Engineering Drive 4, S117576, Singapore., Swa HL; Quantitative Proteomics Group, Institute of Molecular and Cell Biology, Agency for Science Technology and Research, 61 Biopolis Drive, S138673, Singapore., Poh RW; Carl Zeiss Pte Ltd, Microscopy Business Group, Electron Microscopy, 50 Kaki Bukit Place, #05-01, S415926, Singapore., Gunaratne J; Quantitative Proteomics Group, Institute of Molecular and Cell Biology, Agency for Science Technology and Research, 61 Biopolis Drive, S138673, Singapore. Electronic address: jayanthag@imcb.a-star.edu.sg., Bay BH; Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, 4 Medical Drive, Block MD10, S117594, Singapore. Electronic address: boon_huat_bay@nuhs.edu.sg.

Publikováno v: Biomaterials [Biomaterials] 2015 Jan; Vol. 39, pp. 31-8. Date of Electronic Publication: 2014 Nov 13.

NUCKS is a positive transcriptional regulator of insulin signaling.

Autor: Qiu B; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A(∗)STAR), Singapore 138673, Singapore., Shi X; Singapore Bioimaging Consortium, Agency for Science, Technology and Research (A(∗)STAR), Singapore 138667, Singapore., Wong ET; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A(∗)STAR), Singapore 138673, Singapore., Lim J; Singapore Bioimaging Consortium, Agency for Science, Technology and Research (A(∗)STAR), Singapore 138667, Singapore., Bezzi M; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A(∗)STAR), Singapore 138673, Singapore., Low D; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A(∗)STAR), Singapore 138673, Singapore., Zhou Q; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A(∗)STAR), Singapore 138673, Singapore., Akıncılar SC; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A(∗)STAR), Singapore 138673, Singapore., Lakshmanan M; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A(∗)STAR), Singapore 138673, Singapore., Swa HL; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A(∗)STAR), Singapore 138673, Singapore., Tham JM; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A(∗)STAR), Singapore 138673, Singapore., Gunaratne J; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A(∗)STAR), Singapore 138673, Singapore., Cheng KK; State Key Laboratory of Pharmaceutical Biotechnology, Hong Kong, China., Hong W; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A(∗)STAR), Singapore 138673, Singapore., Lam KS; State Key Laboratory of Pharmaceutical Biotechnology, Hong Kong, China., Ikawa M; University of Osaka, Osaka 565-0871, Japan., Guccione E; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A(∗)STAR), Singapore 138673, Singapore., Xu A; State Key Laboratory of Pharmaceutical Biotechnology, Hong Kong, China; Department of Medicine, The University of Hong Kong, Hong Kong, China., Han W; Singapore Bioimaging Consortium, Agency for Science, Technology and Research (A(∗)STAR), Singapore 138667, Singapore; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore. Electronic address: weiping_han@sbic.a-star.edu.sg., Tergaonkar V; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A(∗)STAR), Singapore 138673, Singapore; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore. Electronic address: vinayt@imcb.a-star.edu.sg.

Publikováno v: Cell reports [Cell Rep] 2014 Jun 26; Vol. 7 (6), pp. 1876-86. Date of Electronic Publication: 2014 Jun 12.

Protein interactions of phosphatase and tensin homologue (PTEN) and its cancer-associated G20E mutant compared by using stable isotope labeling by amino acids in cell culture-based parallel affinity purification.

Autor: Gunaratne J; Cancer Science Institute of Singapore, National University of Singapore, 28 Medical Drive, 117456 Singapore., Goh MX, Swa HL, Lee FY, Sanford E, Wong LM, Hogue KA, Blackstock WP, Okumura K

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2011 May 20; Vol. 286 (20), pp. 18093-103. Date of Electronic Publication: 2011 Mar 17.