Výsledky vyhledávání - "Svrkota Bojana"

Akademický článek

Leveraging the power of supercritical fluid chromatography for eco-conscious solutions in pharmaceutical analysis

Autor: Krmar Jovana, Svrkota Bojana, Obradović Darija, Vlatković Vladimir, Lazović Saša, Otašević Biljana

Publikováno v: Arhiv za farmaciju, Vol 74, Iss 2, Pp 133-159 (2024)

Initially employed primarily at a preparative scale for enantiomer separation of chiral drug candidates, Supercritical Fluid Chromatography (SFC) is nowadays extensively used in the analytical mode. Recent advances in SFC separation science have emph

Externí odkaz: https://doaj.org/article/33ec9c46e31b4f7d92f34f6aa4f55b7b

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Akademický článek

Concept of ecologically acceptable chromatographic methods: Case study on the separation of dronedarone hydrochloride and its degradation products

Autor: Đajić Nevena, Krmar Jovana, Stojanović Jevrem, Svrkota Bojana, Otašević Biljana, Malenović Anđelija, Protić Ana

Publikováno v: Arhiv za farmaciju, Vol 74, Iss 2, Pp 235-266 (2024)

Recently, concern about the environmental impact of drug analysis methods has increased significantly. Reversed-phase high-performance liquid chromatography (RP-HPLC), the predominant technique in drug analysis, relies heavily on organic solvents suc

Externí odkaz: https://doaj.org/article/b14e9e83d3ed444fb5ff76f3985e7265

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Akademický článek

Optimization of chromatographic separation of aripiprazole and impurities: Quantitative structure-retention relationship approach

Autor: Svrkota Bojana, Krmar Jovana, Protić Ana, Zečević Mira, Otašević Biljana

Publikováno v: Journal of the Serbian Chemical Society, Vol 87, Iss 5, Pp 615-628 (2022)

A new optimization strategy based on the mixed quantitative structure– retention relationship (QSRR) model is proposed for improving the RPHPLC separation of aripiprazole and its impurities (IMP A-E). Firstly, experimental parameters (EPs), namely

Externí odkaz: https://doaj.org/article/79999f6d5f054258995caeace076e1e8

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Akademický článek

Experimental design in HPLC separation of pharmaceuticals

Autor: Stojanović Jevrem, Krmar Jovana, Protić Ana, Svrkota Bojana, Đajić Nevena, Otašević Biljana

Publikováno v: Arhiv za farmaciju, Vol 71, Iss 4, Pp 279-301 (2021)

Design of Experiments (DoE) is an indispensable tool in contemporary drug analysis as it simultaneously balances a number of chromatographic parameters to ensure optimal separation in High Pressure Liquid Chromatography (HPLC). This manuscript briefl

Externí odkaz: https://doaj.org/article/488790f20c7545028ffc12eb431abfd7

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Akademický článek

The secret of reversed-phase/weak cation exchange retention mechanisms in mixed-mode liquid chromatography applied for small drug molecule analysis

Autor: Svrkota, Bojana, Krmar, Jovana, Protić, Ana, Otašević, Biljana

Publikováno v: In Journal of Chromatography A 8 February 2023 1690

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Akademický článek

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Robust mixed-mode chromatography method development using Analytical Quality by Design approach for analysis of selected drugs

Autor: Svrkota, Bojana, Krmar, Jovana, Protić, Ana, Otašević, Biljana

Publikováno v: Arhiv za farmaciju

Mixed-Mode Liquid Chromatography (MMLC) includes several separation mechanisms in a single column, which is why MMLC can analyze compounds in a broad range of polarities and ionization potentials in a single run (1). Acclaim Mixed-Mode WCX-1 column w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4877::bbb9c054bbf7d7868bcfc27abe43eca2
https://hdl.handle.net/21.15107/rcub_farfar_4524

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Chemometrically supported optimization of RP/WCX-HPLC method

Autor: Svrkota, Bojana, Krmar, Jovana, Đajić, Nevena, Protić, Ana, Otašević, Biljana

Publikováno v: 13th International Symposium on Pharmaceutical Sciences (ISOPS), June 22-25, 2021, Ankara, Turkey

Introduction: Active pharmaceutical ingredients (APIs) are often used in salt form, which is why the inclusion of weak cation exchange (WCX), in addition to reverse-phased (RP) hydrophobic interactions, could improve APIs’ separation (1). Due to th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4877::5857edc720c32096465fc6ab13722fe7
https://farfar.pharmacy.bg.ac.rs/handle/123456789/4692

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Mixed-mode RP/WCX chromatographic system evaluation using QSRR modelling approach

Autor: Svrkota, Bojana, Krmar, Jovana, Protić, Ana, Otašević, Biljana

Publikováno v: 12th International Symposium on Drug Analysis & 32nd International Symposium on Pharmaceutical and Biomedical Analysis, From 11th to 14th September 2022, Mons, Belgium, Abstract book

International Symposium DA-PBA 2022

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4877::2c29103df8d95c7f90bb435490ef4d34
https://hdl.handle.net/21.15107/rcub_farfar_4689

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Building QSRR model for RP/WCX HPLC method developmnet

Autor: Svrkota, Bojana, Krmar, Jovana, Protić, Ana, Otašević, Biljana

Publikováno v: Arhiv za farmaciju

Reverse-phase high-performance liquid chromatography (RP-HPLC) is most common in pharmaceutical analysis and requires significant consumption of toxic mobile phase. Therefore, more eco-friendly solutions are preferred (1). When it comes to complex sa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4877::8d8e8adde6dc311626f17239aaba9b73
https://hdl.handle.net/21.15107/rcub_farfar_4678

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