Výsledky vyhledávání - "Sveva Fornari"

Prion-like spreading of Alzheimer's disease within the brain's connectome

Autor: Sveva Fornari, Mathias Jucker, Ellen Kuhl, Amelie Schäfer, Alain Goriely

Publikováno v: Journal of the Royal Society Interface
Interface 16(159), 20190356 (2019). doi:10.1098/rsif.2019.0356

The prion hypothesis states that misfolded proteins can act as infectious agents that template the misfolding and aggregation of healthy proteins to transmit a disease. Increasing evidence suggests that pathological proteins in neurodegenerative dise

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30fe85f97a3c604a2f2f7ea3e2eb377e
https://ora.ox.ac.uk/objects/uuid:a7533fff-71b4-4fc8-a086-db71b68fb9b0

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Spatially-extended nucleation-aggregation-fragmentation models for the dynamics of prion-like neurodegenerative protein-spreading in the brain and its connectome

Autor: Amelie Schäfer, Ellen Kuhl, Sveva Fornari, Alain Goriely

The prion-like hypothesis of neurodegenerative diseases states that the accumulation of misfolded proteins in the form of aggregates is responsible for tissue death and its associated neurodegenerative pathology and cognitive decline. Some disease-sp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe7a4ca6f638efed1bd541cb75d66602
https://doi.org/10.1101/692038

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